Record No:1
| ACCESS NO | D109593 |
| GENE_NAME | BCL2L11 |
| DESCRIPTION | BCL2 like 11 |
| ALIASES | BAM, BIM, BOD. |
| NCBI_ENTREZ_NO | 10018 |
| UNIPROT_ACCESS_NO | O43521 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | BCL2L11 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein binding, microtubule binding, protein kinase binding, protein heterodimerization activity. |
| GO_BIOLOGICAL_PROCESS | In utero embryonic development, leukocyte homeostasis, B cell homeostasis, B cell apoptotic process, kidney development, protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, lymphocyte homeostasis, myeloid cell homeostasis, apoptotic process, cell-matrix adhesion, spermatogenesis, brain development, male gonad development, intrinsic apoptotic signaling pathway in response to DNA damage, post-embryonic development, positive regulation of cell death, mammary gland development, positive regulation of protein complex assembly, positive regulation of autophagy in response to ER overload, response to endoplasmic reticulum stress, tube formation, odontogenesis of dentin-containing tooth, regulation of apoptotic process, T cell homeostasis, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of neuron apoptotic process, ear development, positive regulation of cell cycle, regulation of organ growth, developmental pigmentation, regulation of developmental pigmentation, spleen development, thymus development, post-embryonic animal organ morphogenesis, positive regulation of apoptotic process by virus, cellular process regulating host cell cycle in response to virus, thymocyte apoptotic process, cellular response to glucocorticoid stimulus, cellular response to estradiol stimulus, positive regulation of release of cytochrome c from mitochondria, extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of mitochondrial membrane permeability involved in apoptotic process, positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, apoptotic process involved in embryonic digit morphogenesis, positive regulation of IRE1-mediated unfolded protein response, cellular response to amyloid-beta, positive regulation of fibroblast apoptotic process, positive regulation of intrinsic apoptotic signaling pathway. |
| BIOGRID_INTERACTION_ID | 115335 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207646 207647 207648 207649 |
| MONOCLONAL_ANTIBODY | Anti-Bim antibody for Human, Mouse, Rat. |