Record No:1
| ACCESS NO | D109612 |
| GENE_NAME | B4GALT1 |
| DESCRIPTION | Beta-1,4-galactosyltransferase 1 |
| ALIASES | B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1. |
| NCBI_ENTREZ_NO | 2683 |
| UNIPROT_ACCESS_NO | P15291 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | B4GALT1 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, N-acetyllactosamine synthase activity, lactose synthase activity, galactosyltransferase activity, transferase activity, transferase activity transferring glycosyl groups, manganese ion binding, UDP-galactosyltransferase activity, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Epithelial cell development, acute inflammatory response, carbohydrate metabolic process, lactose biosynthetic process, galactose metabolic process, protein glycosylation, protein N-linked glycosylation, cell adhesion, binding of sperm to zona pellucida, penetration of zona pellucida, negative regulation of cell proliferation, glycoprotein biosynthetic process, oligosaccharide biosynthetic process, keratan sulfate biosynthetic process, extracellular matrix organization, wound healing, positive regulation of apoptotic process, neutrophil degranulation, development of secondary sexual characteristics, leukocyte migration, protein homooligomerization, regulation of acrosome reaction, positive regulation of epithelial cell proliferation involved in wound healing, angiogenesis involved in wound healing. |
| BIOGRID_INTERACTION_ID | 108950 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207618 207619 |
| MONOCLONAL_ANTIBODY | - |