Record No:1
| ACCESS NO | D109666 |
| GENE_NAME | NR2F6 |
| DESCRIPTION | Nuclear receptor subfamily 2 group F member 6 |
| ALIASES | EAR-2, EAR2, ERBAL2. |
| NCBI_ENTREZ_NO | 2063 |
| UNIPROT_ACCESS_NO | P10588 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | NR2F6 was significantly up regulated in asthmatics as compared to control group. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, DNA-binding transcription factor activity (RNA polymerase II-specific), DNA-binding transcription repressor activity (RNA polymerase II-specific), DNA binding, DNA-binding transcription factor activity, steroid hormone receptor activity, nuclear receptor activity, protein binding, zinc ion binding, sequence-specific DNA binding, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, transcription initiation from RNA polymerase II promoter, signal transduction, cell differentiation, intracellular receptor signaling pathway, entrainment of circadian clock by photoperiod, steroid hormone mediated signaling pathway, neuron development, anatomical structure development, detection of temperature stimulus involved in sensory perception of pain. |
| BIOGRID_INTERACTION_ID | 108375 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 206289 |
| MONOCLONAL_ANTIBODY | Anti-NR2F6/EAR-2 antibody for Human. |