Record No:1
| ACCESS NO | D109676 |
| GENE_NAME | TRIM32 |
| DESCRIPTION | Tripartite motif containing 32 |
| ALIASES | BBS11, HT2A, LGMD2H, LGMDR8, TATIP. |
| NCBI_ENTREZ_NO | 22954 |
| UNIPROT_ACCESS_NO | Q13049 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | TRIM32 expression was increased significantly in asthmatics as compared to allergic rhinitis patients. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Transcription coactivator activity, RNA binding, ubiquitin-protein transferase activity, protein binding, zinc ion binding, transferase activity, myosin binding, Tat protein binding, translation initiation factor binding, identical protein binding, ubiquitin binding, protein self-association. |
| GO_BIOLOGICAL_PROCESS | Protein polyubiquitination, tissue homeostasis, ubiquitin-dependent protein catabolic process, actin ubiquitination, response to UV, protein ubiquitination, positive regulation of cell growth, positive regulation of cell migration, regulation of type I interferon production, negative regulation of viral transcription, response to tumor necrosis factor, positive regulation of I-kappaB kinase/NF-kappaB signaling, innate immune response, fat cell differentiation, positive regulation of neuron differentiation, positive regulation of protein catabolic process, positive regulation of cell cycle, positive regulation of proteolysis, muscle cell cellular homeostasis, negative regulation of fibroblast proliferation, positive regulation of neurogenesis, positive regulation of DNA-binding transcription factor activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of striated muscle cell differentiation, axon development, negative regulation of viral release from host cell, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, positive regulation of tumor necrosis factor-mediated signaling pathway, positive regulation of nucleic acid-templated transcription, positive regulation of interleukin-17-mediated signaling pathway, positive regulation of chemokine (C-C motif) ligand 20 production, positive regulation of cell motility. |
| BIOGRID_INTERACTION_ID | 116608 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207580 207581 |
| MONOCLONAL_ANTIBODY | Anti-TRIM32 antibody for Human, Mouse. |