Record No:1
| ACCESS NO | D111224 |
| GENE_NAME | EHMT2 |
| DESCRIPTION | Euchromatic histone lysine methyltransferase 2 |
| ALIASES | BAT8, C6orf30, G9A, GAT8, KMT1C, NG36. |
| NCBI_ENTREZ_NO | 10919 |
| UNIPROT_ACCESS_NO | Q96KQ7 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Airway Epithelial Cells (AECs) |
| TECHNIQUES | qRT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | EHMT2 expression was up regulated in asthmatics as compared to healthy controls. |
| REFERENCE | 28137284 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II regulatory region sequence-specific DNA binding, p53 binding, protein binding, methyltransferase activity, zinc ion binding, protein-lysine N-methyltransferase activity, transferase activity, histone-lysine N-methyltransferase activity, metal ion binding, histone methyltransferase activity (H3-K9 specific), histone methyltransferase activity (H3-K27 specific), C2H2 zinc finger domain binding, promoter-specific chromatin binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, regulation of DNA replication, DNA methylation, chromatin organization, regulation of transcription by RNA polymerase II, synaptonemal complex assembly, germ cell development, spermatid development, long-term memory, cellular response to starvation, fertilization, DNA methylation on cytosine within a CG sequence, histone methylation, peptidyl-lysine dimethylation, response to nutrient levels, methylation, histone lysine methylation, organ growth, cellular response to drug, phenotypic switching, regulation of DNA methylation, response to ethanol, behavioral response to cocaine, neuron fate specification, histone H3-K9 methylation, regulation of histone H3-K4 methylation, regulation of histone H3-K9 methylation, response to fungicide, negative regulation of G0 to G1 transition, histone H3-K27 methylation, cellular response to cocaine, regulation of signal transduction by p53 class mediator, negative regulation of autophagosome assembly. |
| BIOGRID_INTERACTION_ID | 116123 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 206953 206954 |
| MONOCLONAL_ANTIBODY | Anti-EHMT2/G9A antibody for Human, Mouse, Rat; Anti-EHMT2/G9A+EHMT1/GLP antibody for Human. |