Record No:1
| ACCESS NO | D111599 |
| GENE_NAME | FPR2 |
| DESCRIPTION | Formyl peptide receptor 2 |
| ALIASES | ALXR, FMLP-R-II, FMLPXA, FPRH1, FPRH2, FPRL1, HM63, LXA4R. |
| NCBI_ENTREZ_NO | 2358 |
| UNIPROT_ACCESS_NO | P25090 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Childhood Asthma (Allergic Asthma, Non Allergic Asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells (PBMCs) |
| TECHNIQUES | Microarray, qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE40889 |
| COMMENTS | FPR2 over expression was noted in allergic asthmatics as compared to non allergic asthmatics. |
| REFERENCE | 30102794 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Obsolete signal transducer activity, complement receptor activity, G-protein coupled receptor activity, N-formyl peptide receptor activity, scavenger receptor binding, cargo receptor activity. |
| GO_BIOLOGICAL_PROCESS | Microglial cell activation, positive regulation of protein phosphorylation, complement receptor mediated signaling pathway, receptor-mediated endocytosis, chemotaxis, inflammatory response, cell adhesion, signal transduction, G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cytosolic calcium ion concentration, calcium-mediated signaling, positive regulation of superoxide anion generation, neutrophil degranulation, astrocyte activation, leukocyte migration, positive chemotaxis, cell chemotaxis, positive regulation of 1-phosphatidylinositol-3-kinase activity, positive regulation of ERK1 and ERK2 cascade, positive regulation of monocyte chemotaxis, cellular response to amyloid-beta. |
| BIOGRID_INTERACTION_ID | 108641 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200173 |
| MONOCLONAL_ANTIBODY | Anti-FPRL1/RFP antibody for Horse, Human. |