Record No:1
| ACCESS NO | D112772 |
| GENE_NAME | CPSF1 |
| DESCRIPTION | Cleavage and polyadenylation specific factor 1 |
| ALIASES | CPSF160, HSU37012, MYP27, P/cl.18. |
| NCBI_ENTREZ_NO | 29894 |
| UNIPROT_ACCESS_NO | Q10570 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Severe Asthma |
| SAMPLE | Epithelial Brushings |
| TECHNIQUES | Microarray |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE64913 |
| COMMENTS | CPSF1 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. |
| REFERENCE | 28045928 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Nucleic acid binding, RNA binding, protein binding, enzyme binding, mRNA 3'-UTR AU-rich region binding. |
| GO_BIOLOGICAL_PROCESS | mRNA splicing via spliceosome, termination of RNA polymerase II transcription, mRNA polyadenylation, tRNA splicing via endonucleolytic cleavage and ligation, mRNA processing, mRNA export from nucleus, mRNA 3'-end processing, pre-mRNA cleavage required for polyadenylation. |
| BIOGRID_INTERACTION_ID | 118946 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205532 205533 205534 |
| MONOCLONAL_ANTIBODY | - |