Record No:1
| ACCESS NO | D113727 |
| GENE_NAME | miR-19b-3p |
| DESCRIPTION | MicroRNA 19b-1 |
| ALIASES | C13orf25, MIR17HG, MIR19B, MIRH1, MIRHG1, MIRN19B1, miR-19b-1, miRNA19B1, MIR19B1. |
| NCBI_ENTREZ_NO | 406980 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | Small RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | miR-19b-3p expression was significantly decreased in severe asthmatics as compared to healthy controls. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of inflammatory response to antigenic stimulus, positive regulation of cell proliferation, negative regulation of gene expression, negative regulation of cardiac muscle cell apoptotic process, negative regulation of G2/M transition of mitotic cell cycle, gene silencing by miRNA, miRNA mediated inhibition of translation, positive regulation of tyrosine phosphorylation of STAT protein, cholesterol homeostasis, negative regulation of coagulation, positive regulation of DNA-binding transcription factor activity, positive regulation of cardiac muscle cell proliferation, positive regulation of cell growth involved in cardiac muscle cell development, cellular response to bacterial lipopeptide, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of cholesterol efflux, regulation of plasma lipoprotein particle levels, negative regulation of serine-type endopeptidase activity, negative regulation of interleukin-6 secretion, regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment, negative regulation of reverse cholesterol transport, negative regulation of matrix metallopeptidase secretion, positive regulation of apoptotic process involved in development, negative regulation of apolipoprotein A-I-mediated signaling pathway. |
| BIOGRID_INTERACTION_ID | 135829 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |