Record No:1
| ACCESS NO | D113728 |
| GENE_NAME | miR-20a-5p |
| DESCRIPTION | MicroRNA 20a |
| ALIASES | C13orf25, MIR17HG, MIR20, MIRH1, MIRHG1, MIRN20, MIRN20A, hsa-mir-20, hsa-mir-20a, miR-20, miRNA20A, MIR20A, mir-20a. |
| NCBI_ENTREZ_NO | 406982 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | Small RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | miR-20a-5p expression was significantly decreased in severe asthmatics as compared to healthy controls. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | RNA polymerase II complex binding, mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Outflow tract morphogenesis, negative regulation of protein kinase activity, NOT regulation of cardiac muscle hypertrophy, negative regulation of gene expression, negative regulation of cardiac muscle cell apoptotic process, negative regulation of phosphatidylinositol 3-kinase signaling, negative regulation of BMP signaling pathway, gene silencing by miRNA, miRNA mediated inhibition of translation, cellular response to vascular endothelial growth factor stimulus, positive regulation of angiogenesis, negative regulation of inflammatory response, positive regulation of phagocytosis, negative regulation of stress fiber assembly, negative regulation of protein kinase B signaling, cellular response to lipopolysaccharide, negative regulation of protein serine/threonine kinase activity, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of cardiac muscle hypertrophy in response to stress, negative regulation of sprouting angiogenesis, negative regulation of p38MAPK cascade, positive regulation of vascular smooth muscle cell proliferation, positive regulation of vascular associated smooth muscle cell migration, negative regulation of cardioblast proliferation, negative regulation of interleukin-17 secretion, positive regulation of pulmonary blood vessel remodeling. |
| BIOGRID_INTERACTION_ID | 135831 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |