Record No:1
| ACCESS NO | D113840 |
| GENE_NAME | FERMT1 |
| DESCRIPTION | Fermitin family member 1 |
| ALIASES | C20orf42, DTGCU2, KIND1, UNC112A, URP1. |
| NCBI_ENTREZ_NO | 55612 |
| UNIPROT_ACCESS_NO | Q9BQL6 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Severe Asthma |
| SAMPLE | Airway Epithelial Cells (AECs) |
| TECHNIQUES | Microarray |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE63142, GSE67472 |
| COMMENTS | FERMT1 was up regulated in severe asthma. |
| REFERENCE | 27984699 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Actin filament binding. |
| GO_BIOLOGICAL_PROCESS | Positive regulation of cell-matrix adhesion, cell adhesion, integrin-mediated signaling pathway, negative regulation of gene expression, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of cell adhesion mediated by integrin, negative regulation of protein import into nucleus, keratinocyte proliferation, keratinocyte migration, negative regulation of timing of anagen, basement membrane organization, negative regulation of canonical Wnt signaling pathway, establishment of epithelial cell polarity, negative regulation of stem cell proliferation, positive regulation of transforming growth factor-beta secretion. |
| BIOGRID_INTERACTION_ID | 120752 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205153 |
| MONOCLONAL_ANTIBODY | - |