Record No:1
| ACCESS NO | D113976 |
| GENE_NAME | miR-27b-3p |
| DESCRIPTION | MicroRNA 27b |
| ALIASES | MIR-27b, MIRN27B, miRNA27B, MIR27B. |
| NCBI_ENTREZ_NO | 407019 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | Small RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | miR-27b-3p was significantly decreased in severe asthmatics as compared to healthy controls. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing |
| GO_BIOLOGICAL_PROCESS | Positive regulation of gene expression, negative regulation of gene expression, regulation of cholesterol esterification, negative regulation of low-density lipoprotein particle clearance, negative regulation of monooxygenase activity, gene silencing by miRNA, miRNA mediated inhibition of translation, cellular response to vascular endothelial growth factor stimulus, NIK/NF-kappaB signaling, cholesterol homeostasis, negative regulation of fat cell differentiation, positive regulation of angiogenesis, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation in bone marrow, positive regulation of cell migration involved in sprouting angiogenesis, regulation of superoxide metabolic process, negative regulation of cholesterol efflux, positive regulation of cell adhesion involved in sprouting angiogenesis, negative regulation of lipid binding, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of vascular smooth muscle cell proliferation, negative regulation of low-density lipoprotein particle receptor binding, negative regulation of receptor-mediated endocytosis involved in cholesterol transport. |
| BIOGRID_INTERACTION_ID | - |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |