Record No:1
| ACCESS NO | D114060 |
| GENE_NAME | VDAC1 |
| DESCRIPTION | Voltage dependent anion channel 1 |
| ALIASES | PORIN, VDAC-1. |
| NCBI_ENTREZ_NO | 7416 |
| UNIPROT_ACCESS_NO | P21796 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | VDAC1 was significantly increased in severe asthmatics as compared to control subjects. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Anion channel activity, protein binding, voltage-gated anion channel activity, porin activity, protein kinase binding, identical protein binding, ion channel binding, protein-containing complex binding. |
| GO_BIOLOGICAL_PROCESS | Behavioral fear response, pyruvate metabolic process, ion transport, anion transport, mitochondrial calcium ion transmembrane transport, apoptotic process, chemical synaptic transmission, neuron-neuron synaptic transmission, learning, inorganic anion transport, viral process, macroautophagy, epithelial cell differentiation, transmembrane transport, anion transmembrane transport, regulation of autophagy of mitochondrion, negative regulation of reactive oxygen species metabolic process. |
| BIOGRID_INTERACTION_ID | 113259 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205073 205074 205075 205076 205077 |
| MONOCLONAL_ANTIBODY | Anti-VDAC1 / Porin antibody for Mouse, Rat, Sheep, Goat, Cat, Dog, Human, Pig, Drosophila melanogaster, Fish, Quail, Common marmoset, Dogfish, Catshark, Saccharomyces cerevisiae. |