Record No:1
| ACCESS NO | D114078 |
| GENE_NAME | MAPKAPK5 |
| DESCRIPTION | MAPK activated protein kinase 5 |
| ALIASES | MAPKAP-K5, MK-5, MK5, PRAK. |
| NCBI_ENTREZ_NO | 8550 |
| UNIPROT_ACCESS_NO | Q8IW41 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | MAPKAPK5 was significantly increased in severe asthmatics as compared to control subjects. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Nucleotide binding, p53 binding, protein kinase activity, protein serine/threonine kinase activity, calmodulin-dependent protein kinase activity, MAP kinase kinase activity, protein binding, calmodulin binding, ATP binding, calcium-dependent protein serine/threonine kinase activity, kinase activity, transferase activity, mitogen-activated protein kinase binding. |
| GO_BIOLOGICAL_PROCESS | MAPK cascade, activation of MAPK activity, regulation of translation, protein phosphorylation, signal transduction, Ras protein signal transduction, phosphorylation, peptidyl-serine phosphorylation, negative regulation of TOR signaling, positive regulation of telomere maintenance via telomerase, intracellular signal transduction, protein autophosphorylation, positive regulation of telomerase activity, stress-induced premature senescence, regulation of signal transduction by p53 class mediator, positive regulation of telomere capping. |
| BIOGRID_INTERACTION_ID | 114120 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205048 |
| MONOCLONAL_ANTIBODY | - |