Record No:1
| ACCESS NO | D114103 |
| GENE_NAME | LCLAT1 |
| DESCRIPTION | Lysocardiolipin acyltransferase 1 |
| ALIASES | 1AGPAT8, AGPAT8, ALCAT1, HSRG1849, LYCAT, UNQ1849. |
| NCBI_ENTREZ_NO | 253558 |
| UNIPROT_ACCESS_NO | Q6UWP7 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | LCLAT1 was significantly increased in severe asthmatics as compared to control subjects. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | 1-acylglycerol-3-phosphate O-acyltransferase activity, protein binding, O-acyltransferase activity, transferase activity, transferase activity (transferring acyl groups). |
| GO_BIOLOGICAL_PROCESS | Lipid metabolic process, phosphatidic acid biosynthetic process, multicellular organism development, phospholipid biosynthetic process, CDP-diacylglycerol biosynthetic process, cardiolipin acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling. |
| BIOGRID_INTERACTION_ID | 128972 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205001 |
| MONOCLONAL_ANTIBODY | - |