Record No:1
ACCESS NO | D114146 |
GENE_NAME | PPM1L |
DESCRIPTION | Protein phosphatase, Mg2+/Mn2+ dependent 1L |
ALIASES | PP2C-epsilon, PP2CE, PPM1-LIKE. |
NCBI_ENTREZ_NO | 151742 |
UNIPROT_ACCESS_NO | Q5SGD2 |
ORGANISM | Human |
DISEASE_PHENOTYPE | Asthma |
SAMPLE | Bronchial Epithelial Cells (BECs) |
TECHNIQUES | RNA Sequencing, qRT-PCR |
OMICS | Transcriptomics, Genomics |
STUDY | High Throughput, Low Throughput |
GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
COMMENTS | PPM1L was significantly decreased in severe asthmatics as compared to control subjects. |
REFERENCE | 29769273 |
IMMUNITY_TERM | No |
GO_MOLECULAR_FUNCTION | Catalytic activity, phosphoprotein phosphatase activity, protein serine/threonine phosphatase activity, magnesium-dependent protein serine/threonine phosphatase activity, hydrolase activity, cation binding, metal ion binding. |
GO_BIOLOGICAL_PROCESS | MAPK cascade, protein dephosphorylation, transmembrane receptor protein serine/threonine kinase signaling pathway, sphingolipid biosynthetic process. |
BIOGRID_INTERACTION_ID | 127400 |
SNP_ID | - |
DRUG_ID | - |
STRUCTURE_ID | 204917 |
MONOCLONAL_ANTIBODY | - |