Record No:1


ACCESS NOD114146
GENE_NAMEPPM1L
DESCRIPTIONProtein phosphatase, Mg2+/Mn2+ dependent 1L
ALIASESPP2C-epsilon, PP2CE, PPM1-LIKE.
NCBI_ENTREZ_NO151742
UNIPROT_ACCESS_NOQ5SGD2
ORGANISMHuman
DISEASE_PHENOTYPEAsthma
SAMPLEBronchial Epithelial Cells (BECs)
TECHNIQUESRNA Sequencing, qRT-PCR
OMICSTranscriptomics, Genomics
STUDYHigh Throughput, Low Throughput
GEO_PRIDE_ACCESS_NOGSE85216, GSE85215, GSE85214
COMMENTSPPM1L was significantly decreased in severe asthmatics as compared to control subjects.
REFERENCE29769273
IMMUNITY_TERMNo
GO_MOLECULAR_FUNCTIONCatalytic activity, phosphoprotein phosphatase activity, protein serine/threonine phosphatase activity, magnesium-dependent protein serine/threonine phosphatase activity, hydrolase activity, cation binding, metal ion binding.
GO_BIOLOGICAL_PROCESSMAPK cascade, protein dephosphorylation, transmembrane receptor protein serine/threonine kinase signaling pathway, sphingolipid biosynthetic process.
BIOGRID_INTERACTION_ID127400
SNP_ID-
DRUG_ID-
STRUCTURE_ID204917
MONOCLONAL_ANTIBODY-