Record No:1
| ACCESS NO | D114149 |
| GENE_NAME | CERS2 |
| DESCRIPTION | Ceramide synthase 2 |
| ALIASES | L3, LASS2, SP260, TMSG1. |
| NCBI_ENTREZ_NO | 29956 |
| UNIPROT_ACCESS_NO | Q96G23 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | CERS2 was significantly increased in severe asthmatics as compared to control subjects. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | DNA binding, protein binding, transferase activity, sphingosine N-acyltransferase activity. |
| GO_BIOLOGICAL_PROCESS | Lipid metabolic process, sphingolipid metabolic process, sphingolipid biosynthetic process, ceramide biosynthetic process, negative regulation of axon regeneration, negative regulation of Schwann cell migration, negative regulation of Schwann cell proliferation involved in axon regeneration. |
| BIOGRID_INTERACTION_ID | 118992 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 204914 |
| MONOCLONAL_ANTIBODY | - |