Record No:1


ACCESS NOD114175
GENE_NAMEPLA2G4F
DESCRIPTIONPhospholipase A2 group IVF
ALIASESPLA2G4FZ.
NCBI_ENTREZ_NO255189
UNIPROT_ACCESS_NOQ68DD2
ORGANISMHuman
DISEASE_PHENOTYPEAsthma
SAMPLEBronchial Epithelial Cells (BECs)
TECHNIQUESRNA Sequencing, qRT-PCR
OMICSTranscriptomics, Genomics
STUDYHigh Throughput, Low Throughput
GEO_PRIDE_ACCESS_NOGSE85216, GSE85215, GSE85214
COMMENTSPLA2G4F was significantly decreased in severe asthmatics as compared to control subjects.
REFERENCE29769273
IMMUNITY_TERMNo
GO_MOLECULAR_FUNCTIONPhospholipase activity, phospholipase A2 activity, calcium ion binding, calcium-dependent phospholipid binding, hydrolase activity, metal ion binding, calcium-dependent phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine.
GO_BIOLOGICAL_PROCESSProstaglandin biosynthetic process, lipid metabolic process, phospholipid metabolic process, phospholipid catabolic process, fatty acid transport, lipid catabolic process, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, glycerophospholipid catabolic process, arachidonic acid secretion, cellular response to antibiotic, cellular response to organic cyclic compound.
BIOGRID_INTERACTION_ID129083
SNP_ID-
DRUG_ID-
STRUCTURE_ID204791
MONOCLONAL_ANTIBODY-