Record No:1
| ACCESS NO | D114181 |
| GENE_NAME | TNIP1 |
| DESCRIPTION | TNFAIP3 interacting protein 1 |
| ALIASES | ABIN-1, NAF1, VAN, nip40-1. |
| NCBI_ENTREZ_NO | 10318 |
| UNIPROT_ACCESS_NO | Q15025 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BECs) |
| TECHNIQUES | RNA Sequencing, qRT-PCR |
| OMICS | Transcriptomics, Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | GSE85216, GSE85215, GSE85214 |
| COMMENTS | TNIP1 was significantly increased in severe asthmatics as compared to control subjects. |
| REFERENCE | 29769273 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Protein binding, polyubiquitin modification-dependent protein binding, identical protein binding, mitogen-activated protein kinase binding. |
| GO_BIOLOGICAL_PROCESS | MyD88-dependent toll-like receptor signaling pathway, translation, defense response, inflammatory response, leukocyte cell-cell adhesion, glycoprotein biosynthetic process, protein deubiquitination, negative regulation of I-kappaB kinase/NF-kappaB signaling, negative regulation of viral genome replication, positive regulation of transcription by RNA polymerase II, regulation of inflammatory response, positive regulation of inflammatory response, negative regulation of ERK1 and ERK2 cascade, modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade, positive regulation of protein deubiquitination. |
| BIOGRID_INTERACTION_ID | 115602 |
| SNP_ID | 300704 |
| DRUG_ID | - |
| STRUCTURE_ID | 204257 |
| MONOCLONAL_ANTIBODY | - |