Record No:1
| ACCESS NO | D114242 |
| GENE_NAME | ZBTB20 |
| DESCRIPTION | Zinc finger and BTB domain containing 20 |
| ALIASES | DPZF, HOF, ODA-8S, PRIMS, ZNF288. |
| NCBI_ENTREZ_NO | 26137 |
| UNIPROT_ACCESS_NO | Q9HC78 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Severe Asthma |
| SAMPLE | Peripheral Blood |
| TECHNIQUES | Microarray |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE69683 |
| COMMENTS | ZBTB20 expression was significantly decreased in severe asthmatics as compared to non asthmatic individuals. |
| REFERENCE | 27925796 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity (RNA polymerase II-specific), nucleic acid binding, DNA binding, protein binding, transcription regulatory region DNA binding, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, negative regulation of gene expression, positive regulation of interferon-beta production, positive regulation of interleukin-6 production, positive regulation of tumor necrosis factor production, positive regulation of glycolytic process, negative regulation of DNA-templated transcription, positive regulation of lipid biosynthetic process, lipid homeostasis, cellular response to glucose stimulus. |
| BIOGRID_INTERACTION_ID | 117573 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 204079 |
| MONOCLONAL_ANTIBODY | - |