Record No:1
| ACCESS NO | D114273 |
| GENE_NAME | miR-146a |
| DESCRIPTION | MicroRNA 146a |
| ALIASES | MIRN146, MIRN146A, MIR146A, miRNA146A. |
| NCBI_ENTREZ_NO | 406938 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Atopic Dermatitis |
| SAMPLE | Skin Samples, Keratinocytes |
| TECHNIQUES | Illumina miRNA Universal-16 Expression BeadChip, qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | miR-146a expression is elevated in keratinocytes and skin from patients with Atopic Dermatitis. |
| REFERENCE | 24996260 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of endothelial cell proliferation, positive regulation of gene expression, negative regulation of angiogenesis, gene silencing by miRNA, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of cell migration involved in sprouting angiogenesis, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of apoptotic process in bone marrow, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of cellular senescence. |
| BIOGRID_INTERACTION_ID | 135787 |
| SNP_ID | 300143 300839 |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |