Record No:1
| ACCESS NO | D114402 |
| GENE_NAME | miR-126-5p |
| DESCRIPTION | MicroRNA 126 |
| ALIASES | MIRN126, miRNA126, mir-126, MIR126. |
| NCBI_ENTREZ_NO | 406913 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Allergic Rhinitis |
| SAMPLE | Nasal Mucosa |
| TECHNIQUES | Microarray, qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | miR-126-5p was significantly elevated in allergic rhinitis patients as compared to normal controls. The combination of miR-126-5p, miR-19a-5p and miR-26a-5p could serve as novel biomarkers for Allergic Rhinitis risk. |
| REFERENCE | 31938286 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | RNA polymerase II core binding, mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Positive regulation of phosphatidylinositol 3-kinase signaling, gene silencing by miRNA, positive regulation of MAPK cascade, positive regulation of blood vessel endothelial cell migration, positive regulation of Notch signaling pathway, positive regulation of angiogenesis, negative regulation of inflammatory response, positive regulation of protein kinase B signaling, positive regulation of ERK1 and ERK2 cascade, cellular response to hypoxia, cellular response to laminar fluid shear stress, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of sprouting angiogenesis, positive regulation of vasculature development, negative regulation of vascular endothelial cell proliferation, positive regulation of vascular endothelial cell proliferation, negative regulation of endothelial cell apoptotic process. |
| BIOGRID_INTERACTION_ID | 135762 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |