Record No:1
| ACCESS NO | D114443 |
| GENE_NAME | TIMP1 |
| DESCRIPTION | TIMP metallopeptidase inhibitor 1 |
| ALIASES | CLGI, EPA, EPO, HCI, TIMP, TIMP-1. |
| NCBI_ENTREZ_NO | 7076 |
| UNIPROT_ACCESS_NO | P01033 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Allergic Rhinitis |
| SAMPLE | Nasal Mucosa (of middle turbinate tissues) |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | The expressions of TIMP1 in Allergic Rhinitis tissues were significant increased as compared to that of healthy subjects. |
| REFERENCE | 22667130 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Protease binding, enzyme inhibitor activity, cytokine activity, protein binding, growth factor activity, metalloendopeptidase inhibitor activity, zinc ion binding, peptidase inhibitor activity, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Cell activation, platelet degranulation, aging, positive regulation of cell proliferation, response to hormone, response to organic substance, negative regulation of peptidase activity, regulation of signaling receptor activity, negative regulation of endopeptidase activity, cytokine-mediated signaling pathway, extracellular matrix disassembly, response to cytokine, wound healing, negative regulation of apoptotic process, negative regulation of catalytic activity, response to peptide hormone, post-translational protein modification, cellular protein metabolic process, negative regulation of membrane protein ectodomain proteolysis, cartilage development, negative regulation of trophoblast cell migration, negative regulation of metallopeptidase activity, regulation of integrin-mediated signaling pathway. |
| BIOGRID_INTERACTION_ID | 112932 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 201841 201842 201843 201844 201845 201846 |
| MONOCLONAL_ANTIBODY | Anti-TIMP1 antibody for Mouse, Rat, Human. |