Record No:1
| ACCESS NO | D114608 |
| GENE_NAME | IL5 |
| DESCRIPTION | Interleukin 5 |
| ALIASES | EDF, IL-5, TRF. |
| NCBI_ENTREZ_NO | 3567 |
| UNIPROT_ACCESS_NO | P05113 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Allergic Rhinitis |
| SAMPLE | Nasal Mucosa |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | IL5 expression was significantly increased in patients with persistent allergic rhinitis as compared to intermittent allergic rhinitis patients and normal controls. |
| REFERENCE | 20192943 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Protein tyrosine kinase activity, Ras guanyl-nucleotide exchange factor activity, cytokine activity, interleukin-5 receptor binding, protein binding, growth factor activity. |
| GO_BIOLOGICAL_PROCESS | MAPK cascade, inflammatory response, immune response, positive regulation of cell proliferation, regulation of signaling receptor activity, peptidyl-tyrosine phosphorylation, cytokine-mediated signaling pathway, positive regulation of B cell proliferation, positive regulation of eosinophil differentiation, positive regulation of DNA-templated transcription, positive regulation of JAK-STAT cascade, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of immunoglobulin secretion, positive regulation of DNA binding transcription factor activity, positive regulation of podosome assembly. |
| BIOGRID_INTERACTION_ID | 109781 |
| SNP_ID | - |
| DRUG_ID | 4027 4028 |
| STRUCTURE_ID | 201471 201472 |
| MONOCLONAL_ANTIBODY | Anti-IL-5 antibody for Human, Mouse, Guinea pig. |