Browse Result
Total number of records for Asthma in Serum of Mouse in DAAB (Version-2) database: 146
| Record no | Disease | Organism | Sample | Gene Name | Techniques | Omics | Study | Comments | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Asthma induced by chemicals | Mouse | Serum | Serpinc1 | 2D DIGE and MALDI-TOF-MS | Proteomics | High Throughput | It is known to exert anti-inflammatory effects. In this study It is downregulated in serum of TDI-treated mice suggesting these mice are less able to cope with the neutrophilic inflammation. | 20860378 |
| 2 | Asthma induced by chemicals | Mouse | Serum and Broncho Alveolar Lavage Fluid (BALF) | Hpx | 2D DIGE and MALDI-TOF-MS | Proteomics | High Throughput | In this study hemopexin is upregulated in the serum and BAL fluid of asthmatic mice. It may lead to a stronger activation of CD4 T cells. CD4 T cells are a typical T cell subset related to asthma and increased in auricular lymph nodes of TDI-treated mice. | 20860378 |
| 3 | Asthma induced by chemicals | Mouse | Serum | Apoe | 2D DIGE and MALDI-TOF-MS | Proteomics | High Throughput | It contributes to the protection against oxidative damage. | 20860378 |
| 4 | Asthma induced by chemicals | Mouse | Serum | Gsn | 2D DIGE and MALDI-TOF-MS | Proteomics | High Throughput | This protein is involved In inflammatory response. | 20860378 |
| 5 | Occupational Asthma induced by chemicals | Mouse | Serum | Hpx | 2D DIGE and MALDI-TOF-MS and ELISA | Proteomics | High Throughput and Low Throughput | This a binding/transport protein. | 23038679 |
| 6 | Asthma | Mouse | Serum | Tacr1 | Immunoassay | Others | Low Throughput | NK1-R blockade improved obesity related biomarkers and as well as allergen sensitization and bronchial inflammation. These positive effects support a common pathway in the obese-asthma phenotype and highlight SP as a target with potential clinical interest in the obese-asthma epidemics. | 23176443 |
| 7 | Bronchial Asthma | Mouse | Serum | Il6 | ELISA | Others | Low Throughput | Compared with the control group, the level of Il6 in the serum increased significantly in the asthma model group. | 30591804 |
| 8 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Serum | Il10 | ELISA | Others | Low Throughput | Il10 level in BAL fluid was significantly decreased in asthmatic mice as compared to healthy control mice. | 30373169 |
| 9 | Allergic Asthma | Mouse (BMAL1-LysM-/- mice ) | Lung Tissues, Broncho Alveolar Lavage Fluid (BALF), Serum | Bmal1 | Cell Count, Histology, Cytokine Profiling by ELISA, qRT-PCR | Others, Genomics | Low Throughput | Increased severity of asthma, higher eosinophil numbers and more inflammatory phenotype of asthma was observed in BMAL1-LysM-/- 218 mice. Bmal1 in myeloid cells is a potent negative regulator of allergic asthma. Bmal1 limits myeloid cell responses, which leads to inhibition of allergic asthma. The low expression of BMAL1 at night might explain the increase in asthma during the night. | 28336811 |
| 10 | Bronchial Asthma | Mouse (Female BALB/c mice) | Serum, Lung Tissues, Kidney Tissues | Pge2 | ELISA | Others | Low Throughput | In comparison with the control group, the level of Pge2 in serum and lung tissues, were significantly lower in the bronchial asthma model group. However, Pge2 level in kidney tissue was higher in asthmatic group as compared to the control group. | 30328568 |
| 11 | Bronchial Asthma | Mouse (Female BALB/c mice) | Serum, Lung Tissues, Kidney Tissues | Et1 | ELISA | Others | Low Throughput | In comparison with the control group, the level of Et1 in serum, lung and kidney tissues, were higher in the bronchial asthma model group. | 30328568 |
| 12 | Bronchial Asthma | Mouse (Female BALB/c mice) | Serum, Lung Tissues | Adh | ELISA | Others | Low Throughput | In comparison with the control group, the level of Adh in serum and lung tissue, were higher in the bronchial asthma model group. | 30328568 |
| 13 | Bronchial Asthma | Mouse (Female BALB/c mice) | Serum, Lung Tissues | Anp | ELISA | Others | Low Throughput | In comparison with the control group, the level of Anp in serum and lung tissue, were higher in the bronchial asthma model group. | 30328568 |
| 14 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Ifng | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had reduced expression of Ifng in serum and BALF compared with the normal control mice. | 25440975 |
| 15 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il4 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Il4 in serum and BALF compared with the normal control mice. | 25440975 |
| 16 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il5 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Il5 in serum and BALF compared with the normal control mice. | 25440975 |
| 17 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Mmp9 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had stronger expression of Mmp9 in serum and BALF compared with the normal control mice. | 25440975 |
| 18 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il10 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Il10 in serum and BALF compared with the normal control mice. | 25440975 |
| 19 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il13 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Il13 in serum and BALF compared with the normal control mice. | 25440975 |
| 20 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Tgfb | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Tgfb in serum and BALF compared with the normal control mice. | 25440975 |
| 21 | Allergic Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il12 | ELISA | Others | Low Throughput | The mice that were OVA-sensitized/challenged in the allergic asthma models had higher expression of Il12 in serum and BALF compared with the normal control mice. | 25440975 |
| 22 | Asthma | Mouse (Male C57BL/6J mice) | Serum | Lep | ELISA | Others | Low Throughput | Serum Leptin level was decreased significantly in the OVA induced asthmatic group as compared to the control group. | 30290274 |
| 23 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Ifng | ELISA | Others | Low Throughput | The Wild type mice in all asthma groups had lower Ifng levels in serum and BALF than those in Control group. | 28342933 |
| 24 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il4 | ELISA | Others | Low Throughput | The Wild type mice in all asthma groups had higher Il4 levels in serum and BALF than those in Control group. | 28342933 |
| 25 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il13 | ELISA | Others | Low Throughput | The Wild type mice in all asthma groups had higher Il13 levels in serum and BALF than those in Control group. | 28342933 |
| 26 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Tnfalpha | ELISA | Others | Low Throughput | The Wild type mice in all asthma groups had higher Tnfalpha levels in serum and BALF than those in Control group. | 28342933 |
| 27 | Allergic Asthma | Mouse (Dock8-knockout mice) | Broncho Alveolar Lavage Fluid (BALF), Lung Tissues, Serum | Dock8 | Cell Count, Histopathology, Flow cytometry, ELISA | Others | Low Throughput | Dock8-deficiency may correlate to increased susceptibility and pathogenesis of allergic asthma. | 29702092 |
| 28 | Allergic Asthma | Mouse (Dock8-knockout mice) | Broncho Alveolar Lavage Fluid (BALF), Lung Tissues, Serum | Il21 | Cell Count, Histopathology, Flow cytometry, ELISA | Others | Low Throughput | Nasal treatment with Il21 may offer novel and powerful prophylactic and/or therapeutic moieties to treat Dock8-deficiency-associated allergic asthma. | 29702092 |
| 29 | Obesity related Asthma | Mouse | Broncho Alveolar Lavage Fluid (BALF), Serum | Adipoq | ELISA | Others | Low Throughput | Serum and BALF level of adiponectin was significantly decreased in obesity related asthma mice compared with either asthma mice or obesity mice. Adiponectin level in BALF was higher than in blood serum. | 30584969 |
| 30 | Obesity related Asthma | Mouse | Broncho Alveolar Lavage Fluid (BALF), Serum | Tnf alpha | ELISA | Others | Low Throughput | Serum and BALF level of Tnf alpha was markedly increased in obesity related asthma mice compared with either asthma mice or obesity mice. Tnf alpha level in BALF was higher than in blood serum. | 30584969 |
| 31 | Asthma (OVA Induced Asthma) | Mouse | Serum | Il4 | ELISA | Others | Low Throughput | Il4 level was significantly up regulated in OVA treated blank group of asthmatic mice as compared to control mice. | 30423573 |
| 32 | Asthma (OVA Induced Asthma) | Mouse | Serum | Il6 | ELISA | Others | Low Throughput | Il6 level was significantly up regulated in OVA treated blank group of asthmatic mice as compared to control mice. | 30423573 |
| 33 | Asthma (OVA Induced Asthma) | Mouse | Serum | Il8 | ELISA | Others | Low Throughput | Il8 level was significantly up regulated in OVA treated blank group of asthmatic mice as compared to control mice. | 30423573 |
| 34 | Asthma (OVA Induced Asthma) | Mouse | Serum | Tnf alpha | ELISA | Others | Low Throughput | Tnf alpha level was significantly up regulated in OVA treated blank group of asthmatic mice as compared to control mice. | 30423573 |
| 35 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Il2 | Cytometric Bead Array | Others | High Throughput | Il2 level in serum was reduced significantly in asthma group as compared to control group. | 29916550 |
| 36 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Ifng | Cytometric Bead Array | Others | High Throughput | Ifng level in serum was reduced significantly in asthma group as compared to control group. | 29916550 |
| 37 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Il4 | Cytometric Bead Array | Others | High Throughput | Il4 level in serum was elevated significantly in asthma group as compared to control group. | 29916550 |
| 38 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Il6 | Cytometric Bead Array | Others | High Throughput | Il6 level in serum was elevated significantly in asthma group as compared to control group. | 29916550 |
| 39 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Il10 | Cytometric Bead Array | Others | High Throughput | Il10 level in serum was reduced significantly in asthma group as compared to control group. | 29916550 |
| 40 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Il17a | Cytometric Bead Array | Others | High Throughput | Il17a level in serum was elevated significantly in asthma group as compared to control group. | 29916550 |
| 41 | Bronchial Asthma | Mouse (BALB/c mice) | Serum | Tnf alpha | Cytometric Bead Array | Others | High Throughput | Tnf alpha level in serum was elevated significantly in asthma group as compared to control group. | 29916550 |
| 42 | Asthma (OVA Induced Asthma) | Mouse | Serum | Hdl-c | Hdl-c Assay (Biochemical Test) | Others | Low Throughput | Hdl-c in the sera of the experimental mice was significantly reduced after OVA sensitisation and challenge, implying that asthmatic mice may suffer cholesterol synthesis and transportation problems. | 26318416 |
| 43 | Asthma (OVA Induced Asthma) | Mouse | Serum | Ldl-c | Ldl-c Assay (Biochemical Test) | Others | Low Throughput | Ldl-c in the sera of the experimental mice was significantly reduced after OVA sensitisation and challenge, implying that asthmatic mice may suffer cholesterol synthesis and transportation problems. | 26318416 |
| 44 | Asthma (OVA Induced Asthma) | Mouse | Serum | TC | TC Assay (Biochemical Test) | Others | Low Throughput | TC in the sera of the experimental mice was significantly reduced after OVA sensitisation and challenge, implying that asthmatic mice may suffer cholesterol synthesis and transportation problems. | 26318416 |
| 45 | Stress Exacerbated Asthma (HDM induced asthma) | Mouse (C57BL/6 mice) | Serum | Npy | Enzyme Immunoassay | Others | Low Throughput | The levels of Npy was elevated in the stressed asthma group in comparison with the control and asthma groups. The concentration of Npy was positively correlated with the total leukocyte count and eosinophil numbers. Stress may be associated with elevated peripheral Npy level, which was observed to be associated with exacerbated airway inflammation in asthmatic mice. | 26673939 |
| 46 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il17a | ELISA | Others | Low Throughput | Serum level of Il17a was significantly elevated in OVA induced asthmatic mice as compared to control group. | 29931865 |
| 47 | Asthma (OVA Induced Asthma) | Mouse (Male Swiss Albino mice) | Serum | Ldh | Biochemical Test | Others | Low Throughput | OVA sensitization and repeated challenge induced a significant increase (~3 fold) in serum Ldh activity when compared to the Ldh activity in normal control mice. | 28738246 |
| 48 | Asthma (OVA Induced Asthma) | Mouse (Male Swiss Albino mice) | Serum, Lungs | Cat | Biochemical Test | Others | Low Throughput | OVA sensitization significantly decreased serum and lung catalase activities when compared to those in normal control (by ~2 fold). | 28738246 |
| 49 | Bronchial Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il10 | ELISA | Others | Low Throughput | The level of Il10 in BALF and serum of the mice in the asthma group was significantly reduced as compared to control mice. Il10 level in serum and BALF was positively corelated with Foxp3/Rorγt protein expression ratio. | 28672989 |
| 50 | Bronchial Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Spleen | Il17 | ELISA, Flow Cytometry | Others | Low Throughput | The level of Il17 in BALF and serum of the mice in the asthma group was increased significantly as compared to control mice. The lymphocyte subset CD4+IL-17+ cells/CD4+ T cells in the asthma group were higher than those in the normal control group. Il17 level in serum and BALF was negatively corelated with Foxp3/Rorγt protein expression ratio. | 28672989 |
| 51 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Lung Tissues, Serum | Il5 | qRT-PCR, ELISA | Genomics, Others | Low Throughput | The mRNA expression levels of Il5 was significantly increased in asthmatic mice as compared to control mice. | 28440511 |
| 52 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Lung Tissues, Serum | Il13 | qRT-PCR, ELISA | Genomics, Others | Low Throughput | The mRNA expression levels of Il13 was significantly increased in asthmatic mice as compared to control mice. | 28440511 |
| 53 | Asthma (OVA Induced Asthma) | Mouse (EP2 deficient mice) | Serum | Ep2 | ELISA | Others | Low Throughput | In comparison to WT mice, EP2-deficiency led to a markedly suppressed serum IgE response to OVA challenge. Hyperresponsiveness was greatly suppressed in OVA-challenged EP2 deficient mice. PGE2-EP2-STAT6 signalling pathway plays an important regulatory role in IgE response and allergic response. | 26852804 |
| 54 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Kc | ELISA | Others | Low Throughput | The levels of Kc in the sera was markedly increased in OVA-exposed asthmatic mice and cigerette exposed mice as compared to control group. | 28960099 |
| 55 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Tnfalpha | ELISA | Others | Low Throughput | The levels of Tnfalpha in the sera was markedly increased in OVA-exposed asthmatic mice and cigerette exposed mice as compared to control group. | 28960099 |
| 56 | Asthma (OVA Challenged Asthma, Induced by High-Dose Particulate Matter 2.5) | Mouse (Male BALB/c mice) | Serum | Il10 | ELISA | Others | Low Throughput | ELISA showed that the levels of Il10 in the serum of the OVA asthma group were significantly lower than those in the control group. The Il10 level further decreased significantly upon induction with high dose of particulate matter 2.5. | 29169411 |
| 57 | Asthma (OVA Challenged Asthma, Induced by High-Dose Particulate Matter 2.5) | Mouse (Male BALB/c mice) | Serum | Ifng | ELISA | Others | Low Throughput | ELISA showed that the levels of Ifng in the serum of the OVA asthma group were significantly lower than those in the control group. The Ifng level further decreased significantly upon induction with high dose of particulate matter 2.5. | 29169411 |
| 58 | Asthma (OVA Challenged Asthma, Induced by High-Dose Particulate Matter 2.5) | Mouse (Male BALB/c mice) | Serum | Il17 | ELISA | Others | Low Throughput | ELISA showed that the levels of Il17 in the serum of the OVA asthma group were significantly elevated than those in the control group. The Il17 level further increased significantly upon induction with high dose of particulate matter 2.5. | 29169411 |
| 59 | Asthma (HDM induced asthma) | Mouse (C57BL/6 wild type and Igf1r-deficient mice) | Lung Tissue Homogenate, Serum | Igf1r | qRT-PCR, ELISA | Genomics, Others | Low Throughput | Igf1r deficiency decreases airway inflammation and remodeling after HDM exposure. Igf1r is important in acute asthma pathobiology and resolution of HDM-induced inflammation. | 29272313 |
| 60 | Asthma Exacerbation (OVA induced asthma, Respiratory Syncytial Virus (RSV) mediated exacerbations) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | C5a | ELISA | Others | Low Throughput | C5a levels appeared to be higher in RSV-infected asthma mice as compared with asthma mice and control mice. C5a levels in asthmatic mice was also higher than that in control mice. | 29123203 |
| 61 | Asthma Exacerbation (OVA induced asthma, Respiratory Syncytial Virus (RSV) mediated exacerbations) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il4 | ELISA | Others | Low Throughput | Il4 levels appeared to be higher in RSV-infected asthma mice as compared with asthma mice and control mice. Il4 levels in asthmatic mice was also higher than that in control mice. | 29123203 |
| 62 | Asthma Exacerbation (OVA induced asthma, Respiratory Syncytial Virus (RSV) mediated exacerbations) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Ifng | ELISA | Others | Low Throughput | Ifng levels appeared to be higher in RSV-infected asthma mice as compared with asthma mice and control mice. Ifng levels in asthmatic mice was also higher than that in control mice. | 29123203 |
| 63 | Asthma Exacerbation (OVA induced asthma, Respiratory Syncytial Virus (RSV) mediated exacerbations) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il17a | ELISA | Others | Low Throughput | Il17a levels appeared to be higher in RSV-infected asthma mice as compared with asthma mice and control mice. Il17a levels in asthmatic mice was also higher than that in control mice. | 29123203 |
| 64 | Asthma Exacerbation (OVA induced asthma, Respiratory Syncytial Virus (RSV) mediated exacerbations) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il10 | ELISA | Others | Low Throughput | Il10 levels appeared to be lower in RSV-infected asthma mice as compared with asthma mice and control mice. Il10 levels in asthmatic mice was also lower than that in control mice. | 29123203 |
| 65 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il4 | ELISA | Others | Low Throughput | Il4 level in serum and BALF was significantly increased in OVA treated mice as compared to control mice. Serum and BALF levels of Il4 was further enhanced upon treatment with recombinant human viral (HBoV-VP1u and B19-VP1u) proteins. | 31086415 |
| 66 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il5 | ELISA | Others | Low Throughput | Il5 level in serum and BALF was significantly increased in OVA treated mice as compared to control mice. Serum and BALF levels of Il5 was further enhanced upon treatment with recombinant human viral (HBoV-VP1u and B19-VP1u) proteins. | 31086415 |
| 67 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il13 | ELISA | Others | Low Throughput | Il13 level in serum and BALF was significantly increased in OVA treated mice as compared to control mice. Serum and BALF levels of Il13 was further enhanced upon treatment with recombinant human viral (HBoV-VP1u and B19-VP1u) proteins. | 31086415 |
| 68 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il10 | ELISA | Others | Low Throughput | Il10 level in serum and BALF was significantly increased in OVA treated mice as compared to control mice. Serum and BALF levels of Il10 was further enhanced upon treatment with recombinant human viral (HBoV-VP1u and B19-VP1u) proteins. | 31086415 |
| 69 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Ifng | ELISA | Others | Low Throughput | Ifng level in serum and BALF was significantly increased in OVA treated mice as compared to control mice. Serum and BALF levels of Ifng was further enhanced upon treatment with recombinant human viral (HBoV-VP1u and B19-VP1u) proteins. | 31086415 |
| 70 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF), Splenocytes | Il10 | ELISA | Others | Low Throughput | Il10 level in BALF, serum and splenocytes of OVA treated mice were significantly reduced as compared to control mice. | 31030098 |
| 71 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF), Splenocytes | Il17a | ELISA | Others | Low Throughput | Il17a level in BALF, serum and splenocytes of OVA treated mice were significantly increased as compared to control mice. | 31030098 |
| 72 | Asthma (OVA and HDM induced asthma) | Mouse (C57BL/6 Wild type mice and ALCAM−/− OT-II mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Alcam | ELISA, Immunohistochemistry, Western Blotting, qRT-PCR | Others, Proteomics, Genomics | Low Throughput | Alcam levels were increased in BALF and serum and decreased in lung tissue by OVA treatment in Wild type mice. Inflammatory responses were lower in ALCAM-/- mice than in WT mice. Alcam contributes to OVA-induced allergic asthma by stimulating T-cell activation and proliferation, | 29394080 |
| 73 | Asthma (OVA Induced Asthma) | Mouse (Male C57BL/6 mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il17a | ELISA, Immunohistochemistry, qRT-PCR | Others, Genomics | Low Throughput | Il17a expression was significantly elevated in OVA challenged asthmatic mice as compared to control mice. | 29445341 |
| 74 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Lung Tissue Homogenate, Serum, Lung Tissues | Cd93 | ELISA, Immunohistochemistry | Others | Low Throughput | The OVA model showed a significant decrease in Cd93 levels in lung homogenates, as compared to the control group. The sCd93 level in the serum was increased in the OVA model as compared to that of the control group. Immunohistochemistry revealed an increased Cd93 expression in the OVA model. | 29498549 |
| 75 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 TIMP‐1 KO and WT mice) | Serum, Lung Tissues | Timp1 | ELISA, qRT-PCR, Western Blotting | Others, Genomics, Proteomics | Low Throughput | Timp1 is involved in asthma pathogenesis. Timp Knockout mice had enhanced asthmatic phenotype as compared to wild type mice. | 28992358 |
| 76 | Asthma (OVA Induced Asthma) | Mouse (C57BL/6 TIMP‐1 KO and WT mice) | Serum, Lung Tissues | Gal3 | ELISA, qRT-PCR, Western Blotting | Others, Genomics, Proteomics | Low Throughput | A significant increase in Gal3 levels in OVA‐sensitized animals both in the WT OVA and TIMP‐1 KO OVA mice was observed as compared with the SHAM groups. Gal3 may regulate the IL-17 axis and play a pivotal role in the modulation of inflammation during experimental allergic asthma. | 28992358 |
| 77 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il6 | Protein Cytokine Microarray | Others | High Throughput | Il6 was significantly increased in OVA + vehicle mice compared with those in naive controls. | 30634869 |
| 78 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il17 | Protein Cytokine Microarray | Others | High Throughput | Il17 was significantly increased in OVA + vehicle mice compared with those in naive controls. | 30634869 |
| 79 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Tnfalpha | Protein Cytokine Microarray | Others | High Throughput | Tnfalpha was significantly increased in OVA + vehicle mice compared with those in naive controls. | 30634869 |
| 80 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | G-Csf | Protein Cytokine Microarray | Others | High Throughput | G-Csf was significantly increased in OVA + vehicle mice compared with those in naive controls. | 30634869 |
| 81 | Asthma (OVA Induced Asthma) | Mouse (Male Swiss Albino mice) | Lung Tissue Homogenate, Serum | Cat | Biochemical Test | Others | Low Throughput | Allergic asthma progression induced a significant decrease in lung catalase activity by about 2 folds as compared to normal control mice. | 30286334 |
| 82 | Asthma (OVA Induced Asthma) | Mouse (Male Swiss Albino mice) | Serum | Ldh | Biochemical Test | Others | Low Throughput | Asthmatic mice had a significantly increased serum Ldh activity as compared to normal control by about 3 folds. | 30286334 |
| 83 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il33 | ELISA | Others | Low Throughput | Il33 was significantly elevated in asthmatic mice as compared to healthy controls. | 29581139 |
| 84 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | sSt2 | ELISA | Others | Low Throughput | sSt2 was significantly decreased in asthmatic mice as compared to healthy controls. | 29581139 |
| 85 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Tnfalpha | ELISA | Others | Low Throughput | Tnfalpha was significantly elevated in asthmatic mice as compared to healthy controls. | 29581139 |
| 86 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il1b | ELISA | Others | Low Throughput | Il1b was significantly elevated in asthmatic mice as compared to healthy controls. | 29581139 |
| 87 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il4 | ELISA | Others | Low Throughput | Il4 level was significantly increased in BALF and serum of asthmatic mice as compared to the normal control group. | 29568538 |
| 88 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il5 | ELISA | Others | Low Throughput | Il5 level was significantly increased in BALF and serum of asthmatic mice as compared to the normal control group. | 29568538 |
| 89 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il13 | ELISA | Others | Low Throughput | Il13 level was significantly increased in BALF and serum of asthmatic mice as compared to the normal control group. | 29568538 |
| 90 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Cxcl15 | ELISA | Others | Low Throughput | Cxcl15 level was significantly increased in BALF and serum of asthmatic mice as compared to the normal control group. | 29568538 |
| 91 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Tnfalpha | ELISA | Others | Low Throughput | Tnfalpha level was significantly increased in BALF and serum of asthmatic mice as compared to the normal control group. | 29568538 |
| 92 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il6 | ELISA | Others | Low Throughput | Serum Il6 level was significantly elevated in asthmatic mice as compared to control mice. | 29568538 |
| 93 | Asthma (OVA induced asthma and Ifnb administration) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Trachea, Lymph Nodes | Ifnb | FACS, Bioplex Cytokine Assay | Others | Low Throughput, High Throughput | Ifnb Inhibits the development of allergen tolerance and is Conducive to the development of asthma on subsequent allergen exposure. | 29611236 |
| 94 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Tgfb1 | ELISA | Others | Low Throughput | Tgfb1 level in serum and BALF was significantly increased in OVA induced asthmatic mice as compared to control mice. | 30015827 |
| 95 | Asthma (HDM induced asthma) | Mouse (Female BALB/c mice) | Serum | Il4 | ELISA | Others | Low Throughput | Il4 level was significantly increased in HDM induced asthmatic mice as compared to healthy mice. | 28979688 |
| 96 | Asthma (HDM induced asthma) | Mouse (Female BALB/c mice) | Serum | Il5 | ELISA | Others | Low Throughput | Il5 level was significantly increased in HDM induced asthmatic mice as compared to healthy mice. | 28979688 |
| 97 | Asthma (HDM induced asthma) | Mouse (Female BALB/c mice) | Serum | Il4 | ELISA | Others | Low Throughput | Il4 level was significantly up regulated in serum of HDM induced asthmatic mice as compared to control mice. | 28966674 |
| 98 | Asthma (HDM induced asthma) | Mouse (Female BALB/c mice) | Serum | Il13 | ELISA | Others | Low Throughput | Il13 level was significantly up regulated in serum of HDM induced asthmatic mice as compared to control mice. | 28966674 |
| 99 | Asthma (HDM induced asthma) | Mouse (Female BALB/c mice) | Serum | Ifng | ELISA | Others | Low Throughput | Ifng level was significantly up regulated in serum of HDM induced asthmatic mice as compared to control mice. | 28966674 |
| 100 | Asthma (Aspergillus induced asthma) | Mouse (Claudin-18 Knock out mice) | Serum, Lung Tissues | Cldn18 | ELISA, Histology | Others | Low Throughput | Claudin-18 deficiency increased sensitization to aeroantigens and airway responsiveness in mice. | 27215490 |
| 101 | Asthma (HDM induced asthma) | Mouse (Wild type or Glrx1-/- mice) | Serum, Broncho Alveolar Lavage Fluid (BALF), Lung Tissues, Splenocytes | Glrx1 | ELISA, Histology, qRT-PCR | Others, Genomics | Low Throughput | Glrx1-PSSG axis plays a pivotal role in HDM-induced allergic airways disease in association with enhanced type 2 inflammation and restriction of IFNG and IL17A. | 27035878 |
| 102 | Asthma (OVA Induced Asthma) | Mouse (ICR mice) | Serum, Lung TIssues | Il4 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Il4 expression was significantly increased in OVA treated asthmatic mice as compared to control mice. | 30802215 |
| 103 | Asthma (OVA Induced Asthma) | Mouse (ICR mice) | Serum | Tnfalpha | ELISA | Others | Low Throughput | Tnfalpha expression was significantly increased in OVA treated asthmatic mice as compared to control mice. | 30802215 |
| 104 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Serum | Il1b | ELISA | Others | Low Throughput | The level of Il1b showed a minor but significant decrease in allergen sensitized asthmatic mice as compared to control mice. | 30829405 |
| 105 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Serum | Il6 | ELISA | Others | Low Throughput | The level of Il6 showed a minor but significant decrease in allergen sensitized asthmatic mice as compared to control mice. | 30829405 |
| 106 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Serum | Il5 | ELISA | Others | Low Throughput | The level of Il5 showed an increased expression in allergen sensitized asthmatic mice as compared to control mice. | 30829405 |
| 107 | Asthma (OVA Induced asthma) | Mouse (Female BALB/c mice) | Serum | Il4 | ELISA | Others | Low Throughput | Serum Il4 level was significantly elevated in OVA challenged asthmatic mice as compared to control mice. | 30496840 |
| 108 | Asthma (OVA Induced asthma) | Mouse (Female BALB/c mice) | Serum | Il13 | ELISA | Others | Low Throughput | Serum Il13 level was significantly elevated in OVA challenged asthmatic mice as compared to control mice. | 30496840 |
| 109 | Asthma (OVA + LPS Induced Asthma) | Mouse (BALB/c mice) | Serum | Ast | AST Kinetic Assay (Biochemical Test) | Others | Low Throughput | Ast activity in serum was increased in OVA treated asthma mice as compared to control group. Significant increase in Ast activity was noted in OVA + LPS treated group. | 30470954 |
| 110 | Non eosinophilic Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il4 | ELISA | Others | Low Throughput | Il4 expression in serum and BALF was significantly elevated in asthmatic group as compared to the control group. | 26938767 |
| 111 | Non eosinophilic Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il10 | ELISA | Others | Low Throughput | Il10 expression in serum and BALF was significantly reduced in asthmatic group as compared to the control group. | 26938767 |
| 112 | Non eosinophilic Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il17a | ELISA | Others | Low Throughput | Il17a expression in serum and BALF was significantly elevated in asthmatic group as compared to the control group. | 26938767 |
| 113 | Asthma (OVA Induced Asthma, Particulate Matter 2.5 (PM2.5) Induced Asthma) | Mouse (Male BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il10 | ELISA | Others | Low Throughput | Il10 expression in serum and BALF was significantly reduced in OVA group and PM2.5 group as compared to the control group. | 30124206 |
| 114 | Asthma (OVA Induced Asthma, Particulate Matter 2.5 (PM2.5) Induced Asthma) | Mouse (Male BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il17 | ELISA | Others | Low Throughput | Il17 expression in serum and BALF was significantly elevated in OVA group and PM2.5 group as compared to the control group. | 30124206 |
| 115 | Asthma (HDM Induced Asthma) | Mouse (Male BALB/c mice) | Serum | mMcp1 | ELISA | Others | Low Throughput | Serum mMcp1 was significantly increased in HDM induced asthma model as compared to control group. | 30405619 |
| 116 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il4 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Il4 expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 30360392 |
| 117 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il17 | ELISA | Others | Low Throughput | Il17 level was significantly elevated in OVA Induced asthmatic mice as compared to control mice. | 28674387 |
| 118 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Tgfb | ELISA | Others | Low Throughput | Tgfb level was significantly reduced in OVA Induced asthmatic mice as compared to control mice. | 28674387 |
| 119 | Asthma (OVA Induced Asthma) | Mouse (BALB/c mice) | Lung Tissues, Peritoneal macrophages, Serum | Pon1 | qRT-PCR, Western Blotting, Colorimetric Assay | Genomics, Proteomics, Others | Low Throughput | Pon1 expression and activity was significantly reduced in OVA induced asthmatic mice as compared to control mice. | 28657647 |
| 120 | Asthma (OVA Induced Asthma) | Mouse (Male C57BL/6 mice) | Serum, Lung Tissues, Broncho Alveolar Lavage Fluid (BALF) | mMcp1 | ELISA | Others | Low Throughput | mMcp1 expression was significantly increased in OVA induced asthmatic mice upon exposure to Il33. | 28652606 |
| 121 | Asthma (OVA Induced Asthma) | Mouse (Male C57BL/6 mice) | Serum, Lung Tissues, Broncho Alveolar Lavage Fluid (BALF), Lung Homogenate | Il33 | ELISA | Others | Low Throughput | Il33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma. | 28652606 |
| 122 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF) | Il4 | ELISA, CHIP assay | Others | Low Throughput | Il4 expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 30089474 |
| 123 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Serum | Il1b | ELISA, CHIP assay | Others | Low Throughput | Il1b expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 30089474 |
| 124 | Asthma (OVA Induced Asthma) | Mouse (Male BALB/c mice) | Serum, Broncho Alveolar Lavage Fluid (BALF), Lung Tissues | Il17f | ELISA, CHIP assay, qRT-PCR | Others, Genomics | Low Throughput | Il17f expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 30089474 |
| 125 | Asthma (HDM + OVA Induced Asthma) | Mouse (Wild type and Mbd2 knockout mice) | Spleen, Lung Tissues, Serum | Mbd2 | Western Blotting, qRT-PCR, Flow Cytometry, Immunohistochemistry, ELISA | Proteomics, Genomics, Others | Low Throughput | Mbd2 might facilitate Th17 cell differentiation via down-regulating Socs3 expression in severe asthma. | 30098334 |
| 126 | Asthma (HDM + OVA Induced Asthma) | Mouse (C57BL/6 mice) | Serum | Il17 | ELISA | Others | Low Throughput | Il17 expression was significantly increased in asthmatic mice as compared to control mice. | 30098334 |
| 127 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Tgfb1 | ELISA | Others, Genomics | Low Throughput | Tgfb1 expression was significantly increased in asthmatic mice as compared to control mice. | 30076648 |
| 128 | Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il4 | ELISA | Others | Low Throughput | Il4 level was significantly increased in asthmatic mice as compared to control mice. | 29922428 |
| 129 | Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il5 | ELISA | Others | Low Throughput | Il5 level was significantly increased in asthmatic mice as compared to control mice. | 29922428 |
| 130 | Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il13 | ELISA | Others | Low Throughput | Il13 level was significantly increased in asthmatic mice as compared to control mice. | 29922428 |
| 131 | Asthma | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum | Il17 | ELISA | Others | Low Throughput | Il17 level was significantly increased in asthmatic mice as compared to control mice. | 29922428 |
| 132 | Asthma | Mouse (Female BALB/c mice) | Serum | Tgfb1 | ELISA | Others | Low Throughput | Tgfb1 level was significantly increased in asthmatic mice as compared to control mice. | 29922428 |
| 133 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Lung Tissues | Tslp | ELISA, Western Blotting | Others, Proteomics | Low Throughput | Tslp expression was significantly increased in asthmatic mice as compared to control mice. | 29512368 |
| 134 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum, Lung Tissues | Nfkb | ELISA, Western Blotting | Others, Proteomics | Low Throughput | Nfkb expression was significantly increased in asthmatic mice as compared to control mice. | 29512368 |
| 135 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Il1b | ELISA | Others | Low Throughput | Il1b expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 29512368 |
| 136 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Serum | Tnfalpha | ELISA | Others | Low Throughput | Tnfalpha expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 29512368 |
| 137 | Asthma (OVA Induced Asthma) | Mouse (Wild type and CD4+ CYLDex7/8 mice) | Serum, Lung Tissues | Cyld | ELISA, Histology | Others | Low Throughput | Compared with their wildtype littermates, mice bearing the T cell-specific mutation (CD4+CYLDex7/8) display stronger eosinophilia and mucus production in the lungs and higher IgE serum levels. Blockade of IL9 in CD4+CYLDex7/8 mice alleviates the development of disease symptoms. Thus, by polarization of the T cell cytokine response, sCYLD can favor the development of allergic airway disease. | 27372382 |
| 138 | Asthma (OVA Induced Asthma, HDM Induced Asthma), Atopic Dermatitis (MC903 Induced Atopic Dermatitis) | Mouse (Wild Type and Itln-/- mice) | Broncho Alveolar Lavage Fluid (BALF), Lung Tissues, Ear Tissues, Serum | Itln | ELISA, Flow Cytometry, Immunohistochemistry, qRT-PCR, ELISA | Others, Genomics, Others | Low Throughput | Itln knockdown reduced allergen-induced increases in Il25, Il33 and Tslp and development of type 2 response, eosinophilic inflammation, mucus overproduction and airway hyperresponsiveness. Itln contributes to allergen induced Il25, Il33 and Tslp expression in asthma and atopic dermatitis. | 28224996 |
| 139 | Asthma (OVA Induced Asthma) | Mouse (Wild Type and Bcl2L12-/- mice) | Lung Tissues, Serum, Broncho Alveolar Lavage Fluid (BALF) | Bcl2L12 | Histology, ELISA, Cell Counting | Others | Low Throughput | Mice with Bcl2L12 deficiency do not have asthma. Bcl2-like protein 12 plays a critical role in development of airway allergy through inducing aberrant TH2 polarization. | 30227178 |
| 140 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il4 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Il4 expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 29962952 |
| 141 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il5 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Il5 expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 29962952 |
| 142 | Asthma (OVA Induced Asthma) | Mouse (Female BALB/c mice) | Broncho Alveolar Lavage Fluid (BALF), Serum, Lung Tissues | Il13 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Il13 expression was significantly increased in OVA induced asthmatic mice as compared to control mice. | 29962952 |
| 143 | Asthma (Derf8 or Dust Mite Extract (DME) Induced Asthma) | Mouse | Serum, Lung, Broncho Alveolar Lavage Fluid (BALF) | Il4 | ELISA | Others | Low Throughput | Il4 expression was significantly increased in Derf8 or DME induced asthmatic mice as compared to control mice. | 27532130 |
| 144 | Asthma (Derf8 or Dust Mite Extract (DME) Induced Asthma) | Mouse | Serum, Lung, Broncho Alveolar Lavage Fluid (BALF) | Il5 | ELISA | Others | Low Throughput | Il5 expression was significantly increased in Derf8 or DME induced asthmatic mice as compared to control mice. | 27532130 |
| 145 | Asthma (Derf8 or Dust Mite Extract (DME) Induced Asthma) | Mouse | Serum, Lung, Broncho Alveolar Lavage Fluid (BALF) | Il13 | ELISA | Others | Low Throughput | Il13 expression was significantly increased in Derf8 or DME induced asthmatic mice as compared to control mice. | 27532130 |
| 146 | Asthma (OVA Induced Asthma) | Mouse (Wild type and FcγRIIIA-/- mice) | Serum, Broncho Alveolar Lavage Fluid (BALF), Lung Tissues | FcγRIIIA | ELISA, Cell Counting, Cytomteric Bead Array, qRT-PCR | Others, Genomics | Low Throughput, High Throughput, Low Throughput | Enhanced humoral immune responses typically represented by augmented OVA specific IgG and IgE levels in serum were observed in the absence of FcγRIIIA in the mouse asthma model. FcγRIIIA negatively impacts humoral immune responses but not overall lung Inflammation in OVA induced allergic asthma mouse model. | 29597194 |