Browse Result
Total number of records for Atopic Eczema in Skin Tapings of Human in DAAB (Version-2) database: 9
| Record no | Disease | Organism | Sample | Gene Name | Techniques | Omics | Study | Comments | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | ARG1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It produces urea from L-arginine. Urea is a hygroscopic component of the natural moisturizing factor of human skin. This gene is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum . | 21211653 |
| 2 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | BLMH | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | This protein exhibited a lower expression (although not significant) in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is thought to degrade the filaggrin protein into its constitutent amino acids and these amino acids are the basic components of skin natural moisturizing factor. | 21211653 |
| 3 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | CASP14 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is required for the processing of deiminated filaggrin to produce free acids that moisturizes the skin. Mutation in this gene results in transepidermal water loss and decreased stratum corneum hydration. | 21211653 |
| 4 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | CDSN | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. This lower expression can be an indicative of inappropriate desquamation. | 21211653 |
| 5 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | DSC1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. Thus it acts as a skin barrier. | 21211653 |
| 6 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | DSG1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum. This protein is related to the skin barrier. | 21211653 |
| 7 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | FLG2 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum and nonlesional (with/without eczema) vs nonatopics. This protein is related to the skin barrier. | 21211653 |
| 8 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | GGCT | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It catalyzes the formation of pyroglutamic acid or PCA which is the most abundant cnstituent of natural moisturizing factor in the stratum corneum. | 21211653 |
| 9 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | TGM3 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It mediates the crosslinking of loricrin to small proline rich proteins; this complex further reinforces the cell membrane. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. | 21211653 |