Browse Result
Total number of records for Asthma in Sputum of Human in DAAB (Version-2) database: 929
| Record no | Disease | Organism | Sample | Gene Name | Techniques | Omics | Study | Comments | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Asthma | Human | Sputum | S100A8 | LC-MS/MS and western blot | Proteomics | High Throughput | Less abundant in asthmatic patients. | 21906793 |
| 2 | Asthma | Human | Sputum | S100A9 | LC-MS/MS and western blot | Proteomics | High Throughput and Low Throughput | Less abundant in asthmatic patients. | 21906793 |
| 3 | Asthma | Human | Sputum Eosinophils | EPX | ELISA | Others | Low Throughput | It is specific surrogate marker of eosinophil degranulation and airway eosinophilia. | 23931643 |
| 4 | Asthma | Human | Sputum | HPX | LC MS Western Blot | Proteomics | High Throughput and Low Throughput | an acute-phase heme-binding protein was found to be upregulated in exercise induced sputum of asthmatic patients | 21906793 |
| 5 | Asthma | Human | Sputum | C3 | LC MS Western Blot | Proteomics | High Throughput and Low Throughput | Important chemoattractant for recruitment of leucocytes and upregulated in asthma | 21906793 |
| 6 | Asthma | Human | Sputum | SERPINA1 | LC MS Western Blot | Proteomics | High Throughput and Low Throughput | Involved in airway inflammation and remodelling.Increased in induced sputum of asthamtic patients | 21906793 |
| 7 | Asthma | Human | Sputum | SMR3B | LC MS Western Blot | Proteomics | High Throughput and Low Throughput | Downregulated in asthma patients | 21906793 |
| 8 | Asthma | Human | Sputum | SCGB1A1 | LC MS Western Blot | Proteomics | High Throughput and Low Throughput | Downregulated leading to activation of phospholipase A2 pathway causing bronchial hyperresponsiveness. | 21906793 |
| 9 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | ALPL | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It is a biomarker to discriminate eosinophilic asthma from other asthmatic phenotype. It shows highest expression in neutrophilic asthma. | 24582314 |
| 10 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | BIRC3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 11 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | BPIFB1 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 12 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CCR7 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 13 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CEBPE | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 14 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CLC | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. | 24582314 |
| 15 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CPA3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. | 24582314 |
| 16 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CXCR1 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. Corticosteroids are known to increase the expression of this gene. | 24582314 |
| 17 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | CXCR2 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. Corticosteroids are known to increase the expression of this gene. | 24582314 |
| 18 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | DEFB1 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with paucigranulocytic asthma. | 24582314 |
| 19 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | DNASE1L3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. | 24582314 |
| 20 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | HDC | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 21 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | IL1B | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 22 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | IL1R2 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 23 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | IL1RN | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 24 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | IRAK2 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 25 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | ISG20 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 26 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | NFKB2 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 27 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | NFKBIZ | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 28 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | NLRP3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 29 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | ORM1 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 30 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | PELI1 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 31 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | PI3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It is a biomarkers of neutrophilic asthma. | 24582314 |
| 32 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | TFF3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with eosinophilic asthma. | 24582314 |
| 33 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | TNFAIP3 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It is a biomarkers of neutrophilic asthma. | 24582314 |
| 34 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | TNFRSF1B | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It is a biomarkers of neutrophilic asthma. | 24582314 |
| 35 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | TNFSF14 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | This gene is commonly expresed significantly at high level in all kinds of asthma. | 24582314 |
| 36 | Asthma with eosinophilic and neutrophilic inflammation | Human | Sputum | VNN2 | Microarray and qPCR | Genomics | High Throughput and Low Throughput | It shows highest expression in patients with neutrophilic asthma. | 24582314 |
| 37 | Asthma | Human | Sputum | EPX | ELISA | Others | Low Throughput | Poorly controlled asthma is associated with higher sputum EPX and chronic residential traffic pollution exposure may be associated with eosinophilic but not neutrophilic inflammation. | 23931679 |
| 38 | Asthma-COPD overlap | Human | Sputum | LCN2 | ELISA | Others | Low Throughput | Only sputum NGAL is significantly elevated in COPD-asthma overlap compared with COPD (p=0.00016) and could be used to differentiate patients with overlap from those with COPD. Increased induced sputum levels of NGAL is a characteristic feature of overlap suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap. | 23794464 |
| 39 | Asthma | Human | Sputum | IL6 | ELISA | Others | Low Throughput | It is an indicator of exacerbation. | 23521049 |
| 40 | Asthma | Human | Macrophage from Blood and Sputum | TGM2 | Mass spectrometry and immunoblot | Proteomics, Others | High Throughput and Low Throughput | This gene along with other markers such as MRC1 and CD68 may help to clarify alternative activation heterogeneity of macrophage(local or systemic) in Lung Tissue. It is a potential marker of IL-4 stimulation and a tool to stratify asthmatic patients by FACS analysis of fresh blood or sputum. | 23293084 |
| 41 | Asthma | Human | Sputum | HMGB1 | ELISA | Others | Low Throughput | A neutrophilic chemoattractant and expressed significantly higher in asthmatics. | 21041074 |
| 42 | Asthma | Human | Sputum | RAGE | ELISA | Others | Low Throughput | Inhibitor of RAGE which in turn functions as a ligand for HMGB1. HMGB1 is a potent mediator of inflammation. | 21041074 |
| 43 | Asthma (The effect of aspirin desensitization) | Human | Sputum | TPSAB1 | ImmunoCAP | Others | Low Throughput | Increased significantly during aspirin desensitization. | 20728206 |
| 44 | Asthma (The effect of aspirin desensitization). | Human | Sputum | IL4 | LINCOplex premixed kit | Others | Low Throughput | Decreased significantly after aspirin treatment. | 20728206 |
| 45 | Asthma (The effect of aspirin desensitization). | Human | Sputum | MMP9 | ELISA | Others | Low Throughput | Decreased significantly after aspirin treatment. | 20728206 |
| 46 | Asthma (The effect of aspirin desensitization). | Human | Sputum | TIMP1 | ELISA | Others | Low Throughput | Inhibitor of matrix metalloprotease 9. | 20728206 |
| 47 | Asthma (The effect of aspirin desensitization). | Human | Sputum | FLT3LG | ELISA | Others | Low Throughput | Has an inverse correlation with IL-4. Hence decreases with IL4 increases. | 20728206 |
| 48 | Asthma (Asthmatic Airways). | Human | Sputum | IL6 | RT PCR | Genomics | Low Throughput | Promotes differentiation of CD4 T cells and is elevated in induced sputum. | 20205953 |
| 49 | Asthma (Asthmatic Airways). | Human | Sputum | IL13 | RT PCR | Genomics | Low Throughput | Involved in mucus production and is elevated in asthma. | 20205953 |
| 50 | Childhood Asthma. | Human | Sputum | MMP9 | ELISA | Others | Low Throughput | Upregulated in asthma. | 19788537 |
| 51 | Childhood Asthma. | Human | Sputum | TIMP1 | ELISA | Others | Low Throughput | Upregulated in asthma. | 19788537 |
| 52 | Childhood Asthma. | Human | Sputum | IL8 | ELISA | Others | Low Throughput | Upregulated in asthma. | 19788537 |
| 53 | Severe and non severe Asthma. | Human | Sputum | IL8 | ELISA | Others | Low Throughput | Did not show any marked expression change in severe and non severe asthma. | 19622091 |
| 54 | Severe and non severe Asthma. | Human | Sputum | IL13 | ELISA | Others | Low Throughput | Did not show any marked expression change in severe and non severe asthma. | 19622091 |
| 55 | Asthma | Human | Sputum | IL13 | ELISA | Others | Low Throughput | IL13 levels in sputum supernatant are significantly higher in patients with not well-controlled asthma compared to those with well-controlled asthma and in patients with severe refractory asthma compared to those with mild to-moderate asthma. The diagnostic performance of sputum IL13 is superior to both sputum eosinophils and FeNO levels for the identification of well-controlled asthma, and accordingly, IL13 levels in sputum could serve as a useful biomarker for asthma control assessment. | 26990030 |
| 56 | Asthma | Human | Sputum Macrophages | TSLPR | Immunofluorescent staining | Others | Low Throughput | Immunofluorescence staining of sputum macrophages for TSLPR expression showed higher percentage of CD206 low TSLPR high macrophages as well as CD206 high TSLPR high macrophages in asthma group compared to controls. There is an enhanced expression of TSLPR on sputum macrophages in patients with asthma as compared to control group. Increased expression of TSLPR was related to longer disease duration and impaired lung function. | 30588853 |
| 57 | Asthma | Human | Sputum Macrophages | ST2 | Immunofluorescent staining | Others | Low Throughput | Immunofluorescence staining of sputum macrophages for ST2 expression showed higher percentage of CD206 high ST2 high macrophages in asthma group and higher percentage of CD206 high ST2 low macrophages in controls. There is an enhanced expression of ST2 on sputum macrophages in patients with asthma as compared to control group. Increased expression of ST2 was related to longer disease duration and impaired lung function. | 30588853 |
| 58 | Asthma | Human | Induced Sputum | S100A4 | ELISA | Others | Low Throughput | The S100A4 levels in induced sputum of asthmatics were significantly increased than those of healthy controls and were negatively correlated with some lung function parameters and were positively correlated with sputum eosinophilia and lymphocyte. S100A4 may be involved in the pathogenesis of airway inflammation in asthma. | 30569582 |
| 59 | Asthma | Human | Induced Sputum | GM-CSF | ELISA | Others | Low Throughput | GM‐CSF levels in sputum positively correlated with sputum S100A4 levels. S100A4 levels in induced sputum were significantly higher in patients with asthma as compared to controls. | 30569582 |
| 60 | Asthma | Human | Induced Sputum | CCL24 | ELISA | Others | Low Throughput | Eotaxin 2 levels in sputum positively correlated with sputum S100A4 levels. S100A4 levels in induced sputum were significantly higher in patients with asthma as compared to controls. | 30569582 |
| 61 | Asthma (Allergic asthma) | Human | Nasal Sample, Sputum | IL5 | Nasosorption, Sputosorption | Others | Low Throughput | Sputum and nasal IL-5 levels were significantly higher in Allergic Asthmatics relative to Healthy Controls. | 30335470 |
| 62 | Asthma (Allergic asthma) | Human | Nasal Sample, Sputum | IL8 | Nasosorption, Sputosorption | Others | Low Throughput | Allergic Asthmatics exhibited significantly lower levels of nasosorption CXCL8/IL-8 than Healthy controls. | 30335470 |
| 63 | Severe Asthma | Human | Exhaled Breath Condensate (EBC), Induced Sputum (IS) | POSTN | ELISA | Others | Low Throughput | Higher periostin levels were observed in the EBC and in IS of patients with severe asthma, especially in those from the T2 endotype, when compared with patients with mild to moderate asthma and healthy control subjects, respectively. Airways periostin is a useful marker of severe eosinophilic asthma and may help to phenotype patients that will respond to the biologic agents. | 30336944 |
| 64 | Asthma | Human | Serum, Induced Sputum, Induced Sputum Cells | IL37 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | The expression of IL37 mRNA in asthmatic patients was significantly lower than that observedin healthy controls. IL37 mRNA expression depended on asthma severity. Serum and Induced Sputum IL37levels were significantly lower in asthma patients compared to healthy controls. Theincreased pro-inflammatory cytokines production from asthma Induced Sputum cells was abrogated by the addition of rIL37. IL37 could be an important cytokine in the control of asthma by suppressing the production ofinflammatory cytokines. | 26454413 |
| 65 | Asthma | Human | Culture Supernatant of Induced Sputum Cells, Peripheral Blood Mononuclear Cells (PBMCs) | TNFalpha | ELISA, qRT-PCR | Others, Genomics | Low Throughput | TNFalpha was found to be increased in induced sputum from young asthmatic patients as compared to healthy controls. | 26454413 |
| 66 | Asthma | Human | Culture Supernatant of Induced Sputum Cells, Peripheral Blood Mononuclear Cells (PBMCs) | IL17A | ELISA, qRT-PCR | Others, Genomics | Low Throughput | IL17A was found to be increased in induced sputum from young asthmatic patients as compared to healthy controls. | 26454413 |
| 67 | Asthma | Human | Culture Supernatant of Induced Sputum Cells, Peripheral Blood Mononuclear Cells (PBMCs) | IL1B | ELISA, qRT-PCR | Others, Genomics | Low Throughput | IL1B was found to be increased in induced sputum from young asthmatic patients as compared to healthy controls. | 26454413 |
| 68 | Asthma | Human | Culture Supernatant of Induced Sputum Cells, Peripheral Blood Mononuclear Cells (PBMCs) | IL6 | ELISA, qRT-PCR | Others, Genomics | Low Throughput | IL6 was found to be increased in induced sputum from young asthmatic patients as compared to healthy controls. | 26454413 |
| 69 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | MRPS11 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | MRPS11 belongs to the leading edge genes of the OXPHOS (OXIDATIVE_PHOSPHORYLATION) gene set. The OXPHOS gene set was significantly enriched in cluster 1 of elderly asthma patients with a significantly lower proportion of eosinophils in sputum and less severe airway obstruction. | 30479081 |
| 70 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | HSPA9 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | HSPA9 belongs to the leading edge genes of the OXPHOS (OXIDATIVE_PHOSPHORYLATION) gene set. The OXPHOS gene set was significantly enriched in cluster 1 of elderly asthma patients with a significantly lower proportion of eosinophils in sputum and less severe airway obstruction. | 30479081 |
| 71 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | NUDF4 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | NUDF4 belongs to the leading edge genes of the OXPHOS (OXIDATIVE_PHOSPHORYLATION) gene set. The OXPHOS gene set was significantly enriched in cluster 1 of elderly asthma patients with a significantly lower proportion of eosinophils in sputum and less severe airway obstruction. | 30479081 |
| 72 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | ACTA1 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | ACTA1 belongs to the leading edge genes of the OXPHOS (OXIDATIVE_PHOSPHORYLATION) gene set. The OXPHOS gene set was significantly enriched in cluster 1 of elderly asthma patients with a significantly lower proportion of eosinophils in sputum and less severe airway obstruction. | 30479081 |
| 73 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | SNTB1 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | SNTB1 belongs to the leading edge genes of the EMT (EPITHELIAL MESENCHYMAL TRANSITION) gene set. The EMT gene set was significantly enriched in cluster 2 of elderly asthma patients with a significantly higher proportion of eosinophils in sputum and more severe airway obstruction. | 30479081 |
| 74 | Asthma (Elderly Asthma) | Human | RNA from Induced Sputum Samples | FUCA1 | GeneChip Human Gene 2.0 ST | Genomics | High Throughput | FUCA1 belongs to the leading edge genes of the EMT (EPITHELIAL MESENCHYMAL TRANSITION) gene set. The EMT gene set was significantly enriched in cluster 2 of elderly asthma patients with a significantly higher proportion of eosinophils in sputum and more severe airway obstruction. | 30479081 |
| 75 | Asthma (Mild Atopic Asthma) | Human | Blood and Sputum myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) | IL17RB | Flow cytometry | Others | Low Throughput | IL-17RB is up-regulated on blood and sputum mDCs and pDCs after allergen inhalation in mild atopic asthma patients. | 26625138 |
| 76 | Non-asthmatic eosinophilic bronchitis (NAEB), Eosinophilic Asthma (EA), Non Eosinophilic Asthma (NEA) | Human | Sputum | IL17A | ELISA | Others | Low Throughput | Increasing IL-17A level was found in NAEB group, EA group, and NEA group compared with the healthy control group respectively. Th17-pathway may play a role not only in asthmatics, but also in subjects with NAEB, as reflected by increasing IL-17A concentrations in sputum supernatant. | 30276559 |
| 77 | Neutrophilic Asthma (NA) | Human | Sputum | IL1B | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of IL1B in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 78 | Neutrophilic Asthma (NA) | Human | Sputum | IL6 | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of IL6 in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 79 | Neutrophilic Asthma (NA) | Human | Sputum | IL8 | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of IL8 in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 80 | Neutrophilic Asthma (NA) | Human | Sputum | IL12 | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of IL12 in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 81 | Neutrophilic Asthma (NA) | Human | Sputum | IL17A | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of IL17A in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 82 | Neutrophilic Asthma (NA) | Human | Sputum | TNF alpha | Luminex bead-based assay | Others | High Throughput | Patients with Neutrophilic Asthma demonstrated higher levels of TNF alpha in sputum samples compared with non-Neutrophilic Asthmatics. | 30105264 |
| 83 | Severe Asthma | Human | Sputum Granulocytes, Perpheral Blood Cells (PBCs), Peripheral Blood Eosinophils (PBEs) | LC3-II | Western Blotting, Flow Cytometry | Proteomics, Others | Low Throughput | Immunoblot analysis for the expression of LC3-II in sputum granulocytes revealed that the Severe Asthma (SA) group had significantly higher levels than the Non severe asthma (NSA) and control (NC) group. LC3-II expression in PBCs from the SA and NSA groups was significantly higher than that in PBCs from the NC group. LC3-II expression in PBCs of the SA group tended to be higher than that in PBCs of the NSA group; however, this did not reach statistical significance. The level of autophagy in PBEs from the SA group was significantly higher than that in PBEs from the NC group. The autophagy leve | 26112695 |
| 84 | Asthma-COPD overlap (ACO), Asthma, COPD | Human | Sputum | MPO | ELISA | Others | Low Throughput | In ACO group, the MPO level in sputum was significantly higher than that in the asthma group. In ACO group, sputum MPO level was positively correlated with sputum neutrophil ratio. | 30377121 |
| 85 | Asthma-COPD overlap (ACO), Asthma, COPD | Human | Sputum | ECP | ELISA | Others | Low Throughput | In ACO group, sputum ECP level was significantly higher than that in both the asthma group and COPD group. In ACO group, sputum ECP level is negatively correlated with asthma control and obstructive airflow limitation. | 30377121 |
| 86 | Acute Asthma | Human | Nasal Swabs (Upper Airway), Sputum (Lower Airway) | IL33 | Luminex Assay, Droplet Digital PCR | Others, Genomics | High Throughput, Low Throughput | At the time of exacerbation, upper airway IL33 correlated with upper airway IL5 and IL13 and with lower airway IL13. Similar associations were observed for mRNA expression. Lower airway IL33 positively correlated with lower airway IL13. IL13 and IL33 were positively correlated with FeNO, and IL-5 with eosinophils. The association between IL33 and type-2 cytokines were still present four weeks after exacerbation. IL33 may be driving type-2 inflammation in acute asthma. | 29957280 |
| 87 | Acute Asthma | Human | Nasal Swabs (Upper Airway), Sputum (Lower Airway) | IL13 | Luminex Assay, Droplet Digital PCR | Others, Genomics | High Throughput, Low Throughput | At the time of exacerbation, upper airway IL13 correlated with upper airway IL33. Similar associations were observed for mRNA expression. Lower airway IL13 positively correlated with lower airway IL33. IL13 was positively correlated with FeNO, and IL-5 with eosinophils. | 29957280 |
| 88 | Acute Asthma | Human | Nasal Swabs (Upper Airway), Sputum (Lower Airway) | IL5 | Luminex Assay, Droplet Digital PCR | Others, Genomics | High Throughput, Low Throughput | At the time of exacerbation, upper airway IL5 correlated with upper airway IL33. Similar associations were observed for mRNA expression. IL13 and IL33 were positively correlated with FeNO and IL-5 with eosinophils. | 29957280 |
| 89 | Obese Asthma | Human | Sputum | IL4 | Luminex bead-based assay | Others | High Throughput | IL4 level in sputum was significantly elevated in obese asthmatic subjects as compared with that of lean asthmatic subjects. | 30306746 |
| 90 | Obese Asthma | Human | Sputum | IL13 | Luminex bead-based assay | Others | High Throughput | IL13 level in sputum was significantly elevated in obese asthmatic subjects as compared with that of lean asthmatic subjects. | 30306746 |
| 91 | Obese Asthma | Human | Sputum | IL1B | Luminex bead-based assay | Others | High Throughput | Obese asthmatic subjects had significantly higher IL1B levels as compared with lean asthmatic subjects. | 30306746 |
| 92 | Severe Uncontrolled Pediatric Asthma | Human | Induced Sputum | IL26 | ELISA | Others | Low Throughput | Sputum IL26 level was elevated in severe uncontrolled asthmatics as compared to persistant controlled asthmatics. Sputum IL26 concentrations correlated with those of blood neutrophils. IL-26 is a potential biomarker of disease severity in pediatric asthma without signs of Th2-mediated inflammation. | 27029915 |
| 93 | Asthma (In Children) | Human | Induced Sputum, Sputum Cells, Serum | TSLP | ELISA, qRT-PCR | Others, Genomics | Low Throughput | Serum and Induced sputum fluid TSLP levels was significantly higher in asthmatic patients compared to healthy controls and their levels correlate with asthma severity. The expression of TSLP mRNA in sputum cells of asthmatic patients was significantly higher than that observed in healthy controls | 27528425 |
| 94 | Asthma (In Children) | Human | Induced Sputum | TNFalpha | ELISA | Others | Low Throughput | Induced sputum fluid TNF-α levels was significantly higher in asthmatic patients compared to healthy controls and their levels correlate with asthma severity. | 27528425 |
| 95 | Severe Asthma (SA) | Human | Sputum, Bronchoscopy with Endobronchial Airway Brushings | BDNF | ELISA, Western Blotting, qRT-PCR | Others, Proteomics, Genomics | Low Throughput | Total BDNF mRNA and protein was significantly higher in bronchial epithelial brushings and sputum from SA patients. Significant increases in the expression of BDNF protein, its mature isoform and the exon VIb splice variant in human asthmatic airways in association with airway hyperresponsiveness, asthma severity, and a type 2 cytokine inflammatory signature. | 25945802 |
| 96 | Asthma | Human | Induced Sputum | miR-629-3p | qRT-PCR | Genomics | High Throughput | miR-629-3p was significantly upregulated in sputum of patients with severe asthma compared with that in healthy control subjects and was highest in patients with neutrophilic asthma. | 27155035 |
| 97 | Asthma | Human | Induced Sputum | miR-223-3p | qRT-PCR | Genomics | High Throughput | miR-223-3p was significantly upregulated in sputum of patients with severe asthma compared with that in healthy control subjects and was highest in patients with neutrophilic asthma. miR-223-3p expression was associated also with airway obstruction (FEV1/forced vital capacity). | 27155035 |
| 98 | Asthma | Human | Induced Sputum | miR-142-3p | qRT-PCR | Genomics | High Throughput | miR-142-3p was significantly upregulated in sputum of patients with severe asthma compared with that in healthy control subjects and was highest in patients with neutrophilic asthma. miR-142-3p expression was associated also with airway obstruction (FEV1/forced vital capacity). | 27155035 |
| 99 | Asthma | Human | Induced Sputum | IL1B | Cytometric Bead Array | Others | High Throughput | IL1B levels were significantly increased in sputum of patients with severe asthma and were positively associated with sputum neutrophilia. | 27155035 |
| 100 | Asthma | Human | Induced Sputum | IL8 | Cytometric Bead Array | Others | High Throughput | IL8 protein levels were significantly increased in sputum of patients with severe asthma and were positively associated with sputum neutrophilia. | 27155035 |
| 101 | Asthma | Human | Induced Sputum | IL5 | Cytometric Bead Array | Others | High Throughput | IL5 was increased in patients with mild-to-moderate and those with severe asthma and in patients with eosinophilic asthma as compared to healthy controls. | 27155035 |
| 102 | Severe Eosinophilic Asthma | Human | Sputum | IL5 | Flow Cytometry | Others | Low Throughput | Numbers of ILC2s expressing both IL5 and IL13 are greatest in sputum samples of patients with severe asthma with increased sputum eosinophil numbers despite normalized blood eosinophil numbers. | 26194544 |
| 103 | Severe Eosinophilic Asthma | Human | Sputum | IL13 | Flow Cytometry | Others | Low Throughput | Numbers of ILC2s expressing both IL5 and IL13 are greatest in sputum samples of patients with severe asthma with increased sputum eosinophil numbers despite normalized blood eosinophil numbers. | 26194544 |
| 104 | Asthma | Human | Sputum | CCL11 | ELISA | Others | Low Throughput | A circadian variation in sputum eotaxin was noted, peaking at 4.00 am in asthma group but not in healthy group. | 30156881 |
| 105 | Poorly Controlled Asthma | Human | Nasal Specimen, Pharyngeal Specimen, Induced Sputum | EPX | ELISA | Others | Low Throughput | Nasal and pharyngeal EPX levels are elevated in poorly controlled asthma patients with elevated FeNO levels as compared to normal control subjects. There is a strong association in a given patient between both nasal and pharyngeal EPX levels and the eosinophil percentage of induced sputum. | 26645423 |
| 106 | Asthma | Human | Induced Sputum | CPA3 | Microarray, qRT-PCR | Genomics | High Throughput, Low Throughput | Multivariable logistic regression identified CPA3 as a determinant of eosinophilic asthma. The MCT/CPA3 subtype had elevated exhaled nitric oxide fraction, sputum eosinophils, bronchial sensitivity and reactivity and poorer asthma control. | 26699720 |
| 107 | Childhood Asthma | Human | Induced Sputum | CLU | ELISA | Others | Low Throughput | Children with stable asthma had a higher clusterin level than healthy controls. Clusterin may be a marker that reflects airway inflammation and severity of symptoms and it can be used in the assessment and management of childhood asthma. | 26661728 |
| 108 | Asthma | Human | Induced Sputum | CLC | qRT-PCR | Genomics | Low Throughput | CLC gene expression was reduced following oral corticosteroids (OCS) in asthmatics. | 28663317 |
| 109 | Asthma | Human | Induced Sputum | CPA3 | qRT-PCR | Genomics | Low Throughput | CPA3 gene expression was reduced following oral corticosteroids (OCS) in asthmatics. | 28663317 |
| 110 | Asthma | Human | Broncho Alveolar Lavage Fluid (BALF), Sputum | FXIII | qRT-PCR, Western Blotting | Genomics, Proteomics | Low Throughput | FXIII expression was upregulated in the airways of asthmatic patients after allergen exposure. Expression in the sputum of asthmatic patients correlated with the type 2 immune response and airflow limitation. Excessive activity of FXIII could contribute to the pathophysiology of airway obstruction in asthmatic patients. | 26525229 |
| 111 | Asthma | Human | Sputum | IL-13Rα2 | Microarray | Genomics | High Throughput | IL-13Rα2 is associated with reduced lung function, helper T-cell type 2 gene expression, and airflow obstruction in the airway of individuals with asthma. | 27027964 |
| 112 | Poorly Controlled Asthma | Human | Serum, Sputum | POSTN | ElectroChemiLuminescence Immunoassay (ECLIA), ELISA | Others | Low Throughput | Serum and sputum periostin were significantly higher in patients with eosinophilic asthma as compared with non-eosinophilic asthma. In poorly-controlled asthma, sputum and serum periostin levels are significantly related to sputum eosinophil proportions while their ability to predict the presence of eosinophilic asthma is modest. | 27130294 |
| 113 | Severe Asthma | Human | Induced Sputum | IL18R1 | Microarray, qRT-PCR | Transcriptomics, Genomics | High Throughput, Low Throughput | IL18R1 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. IL18R1 was highest in the eosinophilic, mixed and neutrophilic inflammatory types compared to the pauci-granulocytic group and healthy volunteers. | 28528200 |
| 114 | Severe Asthma | Human | Induced Sputum | IL1RL1 | Microarray, qRT-PCR | Transcriptomics, Genomics | High Throughput, Low Throughput | IL1RL1 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. The expression of IL1RL1 was only significantly higher in the eosinophilic and mixed granulocytic groups. Furthermore, IL1RL1 expression correlated well with the IL-13-induced Th2 gene signature expression. | 28528200 |
| 115 | Severe Asthma | Human | Induced Sputum | CLC | Microarray | Transcriptomics | High Throughput | CLC level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. CLC was also significantly correlated with sputum eosinophils and with the IL13-induced signature. | 28528200 |
| 116 | Severe Asthma | Human | Induced Sputum | IL1R2 | Microarray, qRT-PCR | Transcriptomics, Genomics | High Throughput, Low Throughput | IL1R2 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. IL1R2 was highest in the eosinophilic, mixed and neutrophilic inflammatory types compared to the pauci-granulocytic group and healthy volunteers. | 28528200 |
| 117 | Severe Asthma | Human | Induced Sputum | IL18RAP | Microarray, qRT-PCR | Transcriptomics, Genomics | High Throughput, Low Throughput | IL18RAP level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 118 | Severe Asthma | Human | Induced Sputum | EDN1 | Microarray | Transcriptomics | High Throughput | EDN1 level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 119 | Severe Asthma | Human | Induced Sputum | SAMSN1 | Microarray | Transcriptomics | High Throughput | SAMSN1 level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 120 | Severe Asthma | Human | Induced Sputum | CD24 | Microarray | Transcriptomics | High Throughput | CD24 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. | 28528200 |
| 121 | Severe Asthma | Human | Induced Sputum | SERPINB9 | Microarray | Transcriptomics | High Throughput | SERPINB9 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. | 28528200 |
| 122 | Severe Asthma | Human | Induced Sputum | HIST1H2AC | Microarray | Transcriptomics | High Throughput | HIST1H2AC level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 123 | Severe Asthma | Human | Induced Sputum | IRAK3 | Microarray | Transcriptomics | High Throughput | IRAK3 level was significantly elevated in severe asthmatics as compared to healthy controls. IRAK3 was highest in the eosinophilic, mixed and neutrophilic inflammatory types compared to the pauci-granulocytic group and healthy volunteers. | 28528200 |
| 124 | Severe Asthma | Human | Induced Sputum | RHOH | Microarray | Transcriptomics | High Throughput | RHOH level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. | 28528200 |
| 125 | Severe Asthma | Human | Induced Sputum | PRSS33 | Microarray | Transcriptomics | High Throughput | PRSS33 level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 126 | Severe Asthma | Human | Induced Sputum | P2RY14 | Microarray | Transcriptomics | High Throughput | P2RY14 level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 127 | Severe Asthma | Human | Induced Sputum | NLRP3 | Microarray | Transcriptomics | High Throughput | NLRP3 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. NLRP3 was increased in the eosinophilic, neutrophilic and mixed inflammatory groups compared to the healthy non-asthmatic groups, with its expression being highly significantly correlated only with sputum neutrophils. There was a good correlation between 298 NLRP3 expression and that of Caspase 1, 4 and 5 expression and that of NOD2 and TLR2. There was a significant correlation between NLRP3 gene expression and with members of the IL-1R family. | 28528200 |
| 128 | Severe Asthma | Human | Induced Sputum | TNFAIP3 | Microarray | Transcriptomics | High Throughput | TNFAIP3 level was significantly elevated in severe asthmatics as compared to healthy controls. | 28528200 |
| 129 | Severe Asthma | Human | Induced Sputum | GPR97 | Microarray | Transcriptomics | High Throughput | GPR97 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. | 28528200 |
| 130 | Severe Asthma | Human | Induced Sputum | IL1R1 | Microarray, qRT-PCR | Transcriptomics, Genomics | High Throughput, Low Throughput | IL1R1 level was significantly elevated in severe asthmatics as compared to healthy controls and mild to moderate asthmatics. | 28528200 |
| 131 | Severe Asthma | Human | Induced Sputum | ETS2 | Microarray | Transcriptomics | High Throughput | ETS2 was significantly elevated in non smoking severe asthmatics as compared to healthy subjects. | 28528200 |
| 132 | Severe Asthma | Human | Induced Sputum | RNF144B | Microarray | Transcriptomics | High Throughput | RNF144B was significantly elevated in non smoking severe asthmatics as compared to healthy subjects. | 28528200 |
| 133 | Severe Asthma | Human | Induced Sputum | IL1B | SomaScan | Proteomics | High Throughput | IL1B was elevated in the sputum supernatants of severe asthmatics compared to healthy controls. IL1B was significantly correlated with sputum neutrophil counts. | 28528200 |
| 134 | Severe Asthma | Human | Induced Sputum | IL5 | SomaScan | Proteomics | High Throughput | IL5 expression was increased in severe asthmatics as compared to healthy subjects. | 28528200 |
| 135 | Severe Asthma | Human | Induced Sputum | IL4 | SomaScan | Proteomics | High Throughput | IL-4 was increased in non smoking Severe asthmatics as compared to healthy subjects. | 28528200 |
| 136 | Severe Asthma | Human | Induced Sputum | IL1A | SomaScan | Proteomics | High Throughput | In sputum granulocytes, IL1A protein concentrations was significantly higher in neutrophilic and mixed granulocytic patients compared to the other groups. IL1A was significantly correlated with sputum neutrophil counts. | 28528200 |
| 137 | Severe Asthma | Human | Induced Sputum | PAPP-A | SomaScan | Proteomics | High Throughput | PAPP-A was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 138 | Severe Asthma | Human | Induced Sputum | SAP | SomaScan | Proteomics | High Throughput | SAP was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 139 | Severe Asthma | Human | Induced Sputum | APOA1 | SomaScan | Proteomics | High Throughput | APOA1 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 140 | Severe Asthma | Human | Induced Sputum | PHI | SomaScan | Proteomics | High Throughput | PHI was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 141 | Severe Asthma | Human | Induced Sputum | PGAM1 | SomaScan | Proteomics | High Throughput | Phosphoglycerate mutase 1 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 142 | Severe Asthma | Human | Induced Sputum | VWF | SomaScan | Proteomics | High Throughput | vWF was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 143 | Severe Asthma | Human | Induced Sputum | CAT | SomaScan | Proteomics | High Throughput | Catalase was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 144 | Severe Asthma | Human | Induced Sputum | RETN | SomaScan | Proteomics | High Throughput | Resistin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 145 | Severe Asthma | Human | Induced Sputum | LAG1 | SomaScan | Proteomics | High Throughput | LAG1 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 146 | Severe Asthma | Human | Induced Sputum | LIGHT | SomaScan | Proteomics | High Throughput | LIGHT was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 147 | Severe Asthma | Human | Induced Sputum | CRP | SomaScan | Proteomics | High Throughput | CRP was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 148 | Severe Asthma | Human | Induced Sputum | H1-2 | SomaScan | Proteomics | High Throughput | Histone H1.2 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 149 | Severe Asthma | Human | Induced Sputum | B7-H2 | SomaScan | Proteomics | High Throughput | B7-H2 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 150 | Severe Asthma | Human | Induced Sputum | HP | SomaScan | Proteomics | High Throughput | Haptoglobin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 151 | Severe Asthma | Human | Induced Sputum | FGA | SomaScan | Proteomics | High Throughput | D-dimer (fibrinogen) was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 152 | Severe Asthma | Human | Induced Sputum | CD5L | SomaScan | Proteomics | High Throughput | CD5L was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 153 | Severe Asthma | Human | Induced Sputum | CAPG | SomaScan | Proteomics | High Throughput | CAPG was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 154 | Severe Asthma | Human | Induced Sputum | C5A | SomaScan | Proteomics | High Throughput | C5a was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 155 | Severe Asthma | Human | Induced Sputum | IgD | SomaScan | Proteomics | High Throughput | IgD was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 156 | Severe Asthma | Human | Induced Sputum | HPX | SomaScan | Proteomics | High Throughput | Hemopexin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 157 | Severe Asthma | Human | Induced Sputum | ADIPOQ | SomaScan | Proteomics | High Throughput | Adiponectin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 158 | Severe Asthma | Human | Induced Sputum | APOB | SomaScan | Proteomics | High Throughput | APOB was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 159 | Severe Asthma | Human | Induced Sputum | CXCL8 | SomaScan | Proteomics | High Throughput | CXCL8 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 160 | Severe Asthma | Human | Induced Sputum | MK01 | SomaScan | Proteomics | High Throughput | MK01 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 161 | Severe Asthma | Human | Induced Sputum | FCG2A/B | SomaScan | Proteomics | High Throughput | FCG2A/B was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 162 | Severe Asthma | Human | Induced Sputum | CLM6 | SomaScan | Proteomics | High Throughput | CLM6 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 163 | Severe Asthma | Human | Induced Sputum | CASP3 | SomaScan | Proteomics | High Throughput | CASP3 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 164 | Severe Asthma | Human | Induced Sputum | SERPIND1 | SomaScan | Proteomics | High Throughput | Heparin cofactor II was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 165 | Severe Asthma | Human | Induced Sputum | PBEF | SomaScan | Proteomics | High Throughput | PBEF was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 166 | Severe Asthma | Human | Induced Sputum | PDIA | SomaScan | Proteomics | High Throughput | PDIA was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 167 | Severe Asthma | Human | Induced Sputum | PKC-B-II | SomaScan | Proteomics | High Throughput | PKC-B-II was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 168 | Severe Asthma | Human | Induced Sputum | CDH5 | SomaScan | Proteomics | High Throughput | Cadherin 5 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 169 | Severe Asthma | Human | Induced Sputum | FN1 | SomaScan | Proteomics | High Throughput | Fibronectin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 170 | Severe Asthma | Human | Induced Sputum | GNLY | SomaScan | Proteomics | High Throughput | Granulysin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 171 | Severe Asthma | Human | Induced Sputum | OLR1 | SomaScan | Proteomics | High Throughput | OLR1 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 172 | Severe Asthma | Human | Induced Sputum | A2M | SomaScan | Proteomics | High Throughput | a2-Macroglobulin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 173 | Severe Asthma | Human | Induced Sputum | AZU1 | SomaScan | Proteomics | High Throughput | Azurocidin was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 174 | Severe Asthma | Human | Induced Sputum | GZMB | SomaScan | Proteomics | High Throughput | Granzyme B was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 175 | Severe Asthma | Human | Induced Sputum | CD39 | SomaScan | Proteomics | High Throughput | CD39 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 176 | Severe Asthma | Human | Induced Sputum | TIMP2 | SomaScan | Proteomics | High Throughput | TIMP2 was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 177 | Severe Asthma | Human | Induced Sputum | POSTN | SomaScan | Proteomics | High Throughput | POSTN was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 178 | Severe Asthma | Human | Induced Sputum | PGRP-S | SomaScan | Proteomics | High Throughput | PGRP-S was significantly up-regulated in sputum from Severe Asthmatics as compared to healthy volunteers. | 28528200 |
| 179 | Asthma | Human | Sputum, Broncho Alveolar Lavage Fluid (BALF), Lung Tissues, BAL cells | FSTL1 | Proteomic Array, Immunohistochemistry, qRT-PCR | Proteomics, Others, Genomics | High Throughput, Low Throughput | FSTL1 is >200 fold more highly expressed in the asthma compared to the control subjects. Segmental allergen challenge induced increased levels of BAL FSTL1. BAL macrophages both expressed FSTL1 and could be induced by FSTL1 to express MMP9 suggesting a potential role of FSTL1 in remodeling. | 27001159 |
| 180 | Asthma with Generalized Anxiety Disorder (GAD) | Human | Sputum | IL1 | ELISA | Others | Low Throughput | The sputum IL1 AUC (area under the diurnal variation curve) of the asthma patients with generalized anxiety disorder (GAD) group was significantly higher than the asthma patients without GAD groups and healthy controls. Sputum IL1 AUC concentrations exhibited positive correlation with salivary alpha amylase level and Hamilton anxiety scale (HAMA) scores. | 28716529 |
| 181 | Asthma with Generalized Anxiety Disorder (GAD) | Human | Sputum | IL6 | ELISA | Others | Low Throughput | The sputum IL6 AUC (area under the diurnal variation curve) of the asthma patients with generalized anxiety disorder (GAD) group was significantly higher than the asthma patients without GAD groups and healthy controls. Sputum IL6 AUC concentrations exhibited positive correlation with salivary alpha amylase level and Hamilton anxiety scale (HAMA) scores. | 28716529 |
| 182 | Asthma with Generalized Anxiety Disorder (GAD) | Human | Sputum | sAA | Kinetic Reaction Assay | Others | Low Throughput | The sAA AUC (area under the diurnal variation curve) of the asthma patients with generalized anxiety disorder (GAD) group was significantly higher than the asthma patients without GAD groups and healthy controls. The sAA AUC concentrations exhibited positive correlation with sputum IL1, sputum IL6, salivary alpha amylase level and Hamilton anxiety scale (HAMA) scores. | 28716529 |
| 183 | Asthma with Generalized Anxiety Disorder (GAD) | Human | Sputum | TNFalpha | ELISA | Others | Low Throughput | The sputum TNFalpha AUC (area under the diurnal variation curve) of the asthma patients was significantly higher than healthy controls. | 28716529 |
| 184 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Sputum, Serum | miR145 | qRT-PCR | Genomics | Low Throughput | The expression of miR145 in sputum was higher in asthmatic and COPD patients than in controls. The expression of miR145 in ACOS patients was intermediate between two other groups. No difference was found in the expression of miR145 in the serum among the three groups. | 28694694 |
| 185 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Sputum, Serum | miR338 | qRT-PCR | Genomics | Low Throughput | The expression level of miR338 in the sputum was higher in all patient groups compared to controls. Asthmatics showed a significantly higher miR338 expression compared to COPD patients. The serum of ACOS, COPD patients and asthmatics showed a lower level of miR338 expression as compared to controls. | 28694694 |
| 186 | Asthma | Human | Induced Sputum | A2M | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | A2M was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 187 | Asthma | Human | Induced Sputum | ANXA1 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | ANXA1 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 188 | Asthma | Human | Induced Sputum | APOA2 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | APOA2 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 189 | Asthma | Human | Induced Sputum | ELANE | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | ELANE was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 190 | Asthma | Human | Induced Sputum | GPI | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | GPI was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 191 | Asthma | Human | Induced Sputum | S100A8 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | S100A8 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 192 | Asthma | Human | Induced Sputum | S100A9 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | S100A9 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 193 | Asthma | Human | Induced Sputum | S100A12 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | S100A12 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 194 | Asthma | Human | Induced Sputum | AGT | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | AGT was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 195 | Asthma | Human | Induced Sputum | C5 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | C5 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 196 | Asthma | Human | Induced Sputum | FGA | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | FGA was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 197 | Asthma | Human | Induced Sputum | SERPINF2 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | SERPINF2 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 198 | Asthma | Human | Induced Sputum | APOA1 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | APOA1 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 199 | Asthma | Human | Induced Sputum | CHI3L1 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | CHI3L1 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 200 | Asthma | Human | Induced Sputum | FGB | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | FGB was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 201 | Asthma | Human | Induced Sputum | HPX | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | HPX was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 202 | Asthma | Human | Induced Sputum | ITIH4 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | ITIH4 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 203 | Asthma | Human | Induced Sputum | ORM1 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | ORM1 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 204 | Asthma | Human | Induced Sputum | IL1RN | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | IL1RN was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 205 | Asthma | Human | Induced Sputum | PRG2 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | PRG2 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 206 | Asthma | Human | Induced Sputum | B2M | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | B2M was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 207 | Asthma | Human | Induced Sputum | CTSB | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | CTSB was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 208 | Asthma | Human | Induced Sputum | FN1 | Reverse Phase HPLC-MS/MS | Proteomics | High Throughput | FN1 was significantly elevated in induced sputum of asthmatic patients as compared with controls. | 28778200 |
| 209 | Perimenstrual Asthma (PMA) | Human | Induced Sputum | IL5 | ELISA | Others | Low Throughput | The luteal phase of the cycle in PMA subjects was associated with significantly increased sputum IL5 concentrations when compared to non-PMA asthmatics and healthy controls. | 28752719 |
| 210 | Perimenstrual Asthma (PMA) | Human | Induced Sputum | IL8 | ELISA | Others | Low Throughput | The luteal phase of the cycle in PMA subjects was associated with significantly increased sputum IL8 concentrations when compared to non-PMA asthmatics and healthy controls. | 28752719 |
| 211 | Asthma | Human | Induced Sputum | TNFalpha | qRT-PCR | Genomics | Low Throughput | Levels of TNFalpha was significantly increased in participants with neutrophilic asthma compared eosinophilic asthma. | 27036916 |
| 212 | Asthma | Human | Induced Sputum | MCP1 | qRT-PCR | Genomics | Low Throughput | MCP1 levels was also higher in neutrophilic asthma as compared to eosinophilic asthma. | 27036916 |
| 213 | Asthma | Human | Sputum | S100A9 | ELISA | Others | Low Throughput | S100A9 level in sputum was significantly higher in asthmatics as compared to normal controls. The median S100A9 level was increased in the neutrophil dominant group as compared to the eosinophil dominant group and the pauci-granulocytic group of asthmatics. The levels of S100A9 were significantly correlated with percentages of neutrophils in sputum. S100A9 plays a vital role to initiate and amplify the neutrophilic inflammation in asthma. | 28847516 |
| 214 | Severe Asthma | Human | Sputum | CD14 | Microarray, qRT-PCR | Genomics | High Throughput, Low Throughput | CD14 was significantly overexpressed in sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 215 | Severe Asthma | Human | Sputum | TLR2 | Microarray, qRT-PCR | Genomics | High Throughput, Low Throughput | TLR2 was significantly overexpressed in sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 216 | Mild Asthma | Human | Sputum | ARHGEF33 | Microarray | Genomics | High Throughput | ARHGEF33 was significantly down regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 217 | Mild Asthma | Human | Sputum | CREBBP | Microarray | Genomics | High Throughput | CREBBP was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 218 | Mild Asthma | Human | Sputum | TRNAU1AP | Microarray | Genomics | High Throughput | TRNAU1AP was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 219 | Mild Asthma | Human | Sputum | BUB3 | Microarray | Genomics | High Throughput | BUB3 was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 220 | Mild Asthma | Human | Sputum | SLC25A28 | Microarray | Genomics | High Throughput | SLC25A28 was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 221 | Mild Asthma | Human | Sputum | RBBP8 | Microarray | Genomics | High Throughput | RBBP8 was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 222 | Mild Asthma | Human | Sputum | SLC39A14 | Microarray | Genomics | High Throughput | SLC39A14 was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 223 | Mild Asthma | Human | Sputum | CLPX | Microarray | Genomics | High Throughput | CLPX was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 224 | Mild Asthma | Human | Sputum | KIF20B | Microarray | Genomics | High Throughput | KIF20B was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 225 | Mild Asthma | Human | Sputum | FAM8A1 | Microarray | Genomics | High Throughput | FAM8A1 was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 226 | Mild Asthma | Human | Sputum | SH2D3C | Microarray | Genomics | High Throughput | SH2D3C was significantly up regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 227 | Mild Asthma | Human | Sputum | LOC377711 | Microarray | Genomics | High Throughput | LOC377711 was significantly down regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 228 | Mild Asthma | Human | Sputum | TDRD5 | Microarray | Genomics | High Throughput | TDRD5 was significantly down regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 229 | Mild Asthma | Human | Sputum | COLGALT2 | Microarray | Genomics | High Throughput | COLGALT2 was significantly down regulated in sputum of mild asthmatics as compared to healthy subjects. | 28933920 |
| 230 | Moderate Asthma | Human | Sputum | CCL17 | Microarray | Genomics | High Throughput | CCL17 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 231 | Moderate Asthma | Human | Sputum | MFN1 | Microarray | Genomics | High Throughput | MFN1 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 232 | Moderate Asthma | Human | Sputum | MXI1 | Microarray | Genomics | High Throughput | MXI1 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 233 | Moderate Asthma | Human | Sputum | PDCD4 | Microarray | Genomics | High Throughput | PDCD4 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 234 | Moderate Asthma | Human | Sputum | SMIM14 | Microarray | Genomics | High Throughput | SMIM14 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 235 | Moderate Asthma | Human | Sputum | MINOS1P1 | Microarray | Genomics | High Throughput | MINOS1P1 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 236 | Moderate Asthma | Human | Sputum | CD14 | Microarray | Genomics | High Throughput | CD14 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 237 | Moderate Asthma | Human | Sputum | NEDD9 | Microarray | Genomics | High Throughput | NEDD9 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 238 | Moderate Asthma | Human | Sputum | KBTBD8 | Microarray | Genomics | High Throughput | KBTBD8 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 239 | Moderate Asthma | Human | Sputum | FAM8A1 | Microarray | Genomics | High Throughput | FAM8A1 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 240 | Moderate Asthma | Human | Sputum | CD8B | Microarray | Genomics | High Throughput | CD8B was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 241 | Moderate Asthma | Human | Sputum | ARNTL | Microarray | Genomics | High Throughput | ARNTL was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 242 | Moderate Asthma | Human | Sputum | OTTHUMG00000162185 | Microarray | Genomics | High Throughput | OTTHUMG00000162185 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 243 | Moderate Asthma | Human | Sputum | TMEM243 | Microarray | Genomics | High Throughput | TMEM243 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 244 | Moderate Asthma | Human | Sputum | ZNF582 | Microarray | Genomics | High Throughput | ZNF582 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 245 | Moderate Asthma | Human | Sputum | BTG3 | Microarray | Genomics | High Throughput | BTG3 was significantly up regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 246 | Moderate Asthma | Human | Sputum | MRGPRX3 | Microarray | Genomics | High Throughput | MRGPRX3 was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 247 | Moderate Asthma | Human | Sputum | PSG6 | Microarray | Genomics | High Throughput | PSG6 was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 248 | Moderate Asthma | Human | Sputum | GNRHR | Microarray | Genomics | High Throughput | GNRHR was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 249 | Moderate Asthma | Human | Sputum | VPS26B | Microarray | Genomics | High Throughput | VPS26B was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 250 | Moderate Asthma | Human | Sputum | C1ORF159 | Microarray | Genomics | High Throughput | C1ORF159 was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 251 | Moderate Asthma | Human | Sputum | ARHGEF33 | Microarray | Genomics | High Throughput | ARHGEF33 was significantly down regulated in moderate asthmatics as compared to healthy subjects. | 28933920 |
| 252 | Severe Asthma | Human | Sputum | TPRKB | Microarray | Genomics | High Throughput | TPRKB was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 253 | Severe Asthma | Human | Sputum | SLC31A2 | Microarray | Genomics | High Throughput | SLC31A2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 254 | Severe Asthma | Human | Sputum | BNIP3L | Microarray | Genomics | High Throughput | BNIP3L was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 255 | Severe Asthma | Human | Sputum | FLVCR1-AS1 | Microarray | Genomics | High Throughput | FLVCR1-AS1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 256 | Severe Asthma | Human | Sputum | ENTPD1 | Microarray | Genomics | High Throughput | ENTPD1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 257 | Severe Asthma | Human | Sputum | FCER1G | Microarray | Genomics | High Throughput | FCER1G was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 258 | Severe Asthma | Human | Sputum | LMO4 | Microarray | Genomics | High Throughput | LMO4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 259 | Severe Asthma | Human | Sputum | CD84 | Microarray | Genomics | High Throughput | CD84 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 260 | Severe Asthma | Human | Sputum | FBP1 | Microarray | Genomics | High Throughput | FBP1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 261 | Severe Asthma | Human | Sputum | SNHG1 | Microarray | Genomics | High Throughput | SNHG1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 262 | Severe Asthma | Human | Sputum | ARNTL | Microarray | Genomics | High Throughput | ARNTL was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 263 | Severe Asthma | Human | Sputum | F11R | Microarray | Genomics | High Throughput | F11R was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 264 | Severe Asthma | Human | Sputum | NUS1 | Microarray | Genomics | High Throughput | NUS1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 265 | Severe Asthma | Human | Sputum | MSR1 | Microarray | Genomics | High Throughput | MSR1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 266 | Severe Asthma | Human | Sputum | RELA | Microarray | Genomics | High Throughput | RELA was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 267 | Severe Asthma | Human | Sputum | SCML4 | Microarray | Genomics | High Throughput | SCML4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 268 | Severe Asthma | Human | Sputum | TAOK1 | Microarray | Genomics | High Throughput | TAOK1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 269 | Severe Asthma | Human | Sputum | PSIP1 | Microarray | Genomics | High Throughput | PSIP1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 270 | Severe Asthma | Human | Sputum | CCRL2 | Microarray | Genomics | High Throughput | CCRL2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 271 | Severe Asthma | Human | Sputum | MAPK6 | Microarray | Genomics | High Throughput | MAPK6 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 272 | Severe Asthma | Human | Sputum | HIAT1 | Microarray | Genomics | High Throughput | HIAT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 273 | Severe Asthma | Human | Sputum | CLINT1 | Microarray | Genomics | High Throughput | CLINT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 274 | Severe Asthma | Human | Sputum | SOLH | Microarray | Genomics | High Throughput | SOLH was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 275 | Severe Asthma | Human | Sputum | PAN3 | Microarray | Genomics | High Throughput | PAN3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 276 | Severe Asthma | Human | Sputum | LRRC8C | Microarray | Genomics | High Throughput | LRRC8C was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 277 | Severe Asthma | Human | Sputum | PIGF | Microarray | Genomics | High Throughput | PIGF was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 278 | Severe Asthma | Human | Sputum | CORO1C | Microarray | Genomics | High Throughput | CORO1C was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 279 | Severe Asthma | Human | Sputum | EMR2 | Microarray | Genomics | High Throughput | EMR2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 280 | Severe Asthma | Human | Sputum | PTGS2 | Microarray | Genomics | High Throughput | PTGS2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 281 | Severe Asthma | Human | Sputum | CLEC5A | Microarray | Genomics | High Throughput | CLEC5A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 282 | Severe Asthma | Human | Sputum | ZNF639 | Microarray | Genomics | High Throughput | ZNF639 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 283 | Severe Asthma | Human | Sputum | LINC00621 | Microarray | Genomics | High Throughput | LINC00621 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 284 | Severe Asthma | Human | Sputum | ACTR5 | Microarray | Genomics | High Throughput | ACTR5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 285 | Severe Asthma | Human | Sputum | CEP135 | Microarray | Genomics | High Throughput | CEP135 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 286 | Severe Asthma | Human | Sputum | EIF4G3 | Microarray | Genomics | High Throughput | EIF4G3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 287 | Severe Asthma | Human | Sputum | CCL4 | Microarray | Genomics | High Throughput | CCL4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 288 | Severe Asthma | Human | Sputum | TACC1 | Microarray | Genomics | High Throughput | TACC1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 289 | Severe Asthma | Human | Sputum | NDUFB1 | Microarray | Genomics | High Throughput | NDUFB1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 290 | Severe Asthma | Human | Sputum | CD8B | Microarray | Genomics | High Throughput | CD8B was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 291 | Severe Asthma | Human | Sputum | HERPUD2 | Microarray | Genomics | High Throughput | HERPUD2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 292 | Severe Asthma | Human | Sputum | LOC100506639 | Microarray | Genomics | High Throughput | LOC100506639 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 293 | Severe Asthma | Human | Sputum | PI3 | Microarray | Genomics | High Throughput | PI3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 294 | Severe Asthma | Human | Sputum | FCGR3A | Microarray | Genomics | High Throughput | FCGR3A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 295 | Severe Asthma | Human | Sputum | CIRH1A | Microarray | Genomics | High Throughput | CIRH1A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 296 | Severe Asthma | Human | Sputum | ZNF641 | Microarray | Genomics | High Throughput | ZNF641 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 297 | Severe Asthma | Human | Sputum | ZNF385A | Microarray | Genomics | High Throughput | ZNF385A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 298 | Severe Asthma | Human | Sputum | SP3 | Microarray | Genomics | High Throughput | SP3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 299 | Severe Asthma | Human | Sputum | POLR3F | Microarray | Genomics | High Throughput | POLR3F was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 300 | Severe Asthma | Human | Sputum | PHTF2 | Microarray | Genomics | High Throughput | PHTF2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 301 | Severe Asthma | Human | Sputum | SKP1 | Microarray | Genomics | High Throughput | SKP1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 302 | Severe Asthma | Human | Sputum | SPINK1 | Microarray | Genomics | High Throughput | SPINK1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 303 | Severe Asthma | Human | Sputum | PDE4D | Microarray | Genomics | High Throughput | PDE4D was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 304 | Severe Asthma | Human | Sputum | GLRX5 | Microarray | Genomics | High Throughput | GLRX5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 305 | Severe Asthma | Human | Sputum | CPVL | Microarray | Genomics | High Throughput | CPVL was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 306 | Severe Asthma | Human | Sputum | BUB3 | Microarray | Genomics | High Throughput | BUB3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 307 | Severe Asthma | Human | Sputum | PHF21A | Microarray | Genomics | High Throughput | PHF21A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 308 | Severe Asthma | Human | Sputum | SPOPL | Microarray | Genomics | High Throughput | SPOPL was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 309 | Severe Asthma | Human | Sputum | RABGAP1L | Microarray | Genomics | High Throughput | RABGAP1L was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 310 | Severe Asthma | Human | Sputum | PHLDA1 | Microarray | Genomics | High Throughput | PHLDA1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 311 | Severe Asthma | Human | Sputum | RALA | Microarray | Genomics | High Throughput | RALA was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 312 | Severe Asthma | Human | Sputum | NDUFV3 | Microarray | Genomics | High Throughput | NDUFV3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 313 | Severe Asthma | Human | Sputum | TREM1 | Microarray | Genomics | High Throughput | TREM1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 314 | Severe Asthma | Human | Sputum | RNF13 | Microarray | Genomics | High Throughput | RNF13 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 315 | Severe Asthma | Human | Sputum | DBF4 | Microarray | Genomics | High Throughput | DBF4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 316 | Severe Asthma | Human | Sputum | PPTC7 | Microarray | Genomics | High Throughput | PPTC7 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 317 | Severe Asthma | Human | Sputum | ITGAX | Microarray | Genomics | High Throughput | ITGAX was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 318 | Severe Asthma | Human | Sputum | ANKRD1 | Microarray | Genomics | High Throughput | ANKRD1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 319 | Severe Asthma | Human | Sputum | ACBD3 | Microarray | Genomics | High Throughput | ACBD3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 320 | Severe Asthma | Human | Sputum | SPO11 | Microarray | Genomics | High Throughput | SPO11 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 321 | Severe Asthma | Human | Sputum | ALG5 | Microarray | Genomics | High Throughput | ALG5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 322 | Severe Asthma | Human | Sputum | OTTHUMG00000175664 | Microarray | Genomics | High Throughput | OTTHUMG00000175664 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 323 | Severe Asthma | Human | Sputum | MROH1 | Microarray | Genomics | High Throughput | MROH1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 324 | Severe Asthma | Human | Sputum | SPINT2 | Microarray | Genomics | High Throughput | SPINT2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 325 | Severe Asthma | Human | Sputum | LINC00877 | Microarray | Genomics | High Throughput | LINC00877 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 326 | Severe Asthma | Human | Sputum | CNEP1R1 | Microarray | Genomics | High Throughput | CNEP1R1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 327 | Severe Asthma | Human | Sputum | LOC100133920 | Microarray | Genomics | High Throughput | LOC100133920 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 328 | Severe Asthma | Human | Sputum | ZNF747 | Microarray | Genomics | High Throughput | ZNF747 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 329 | Severe Asthma | Human | Sputum | ENDOU | Microarray | Genomics | High Throughput | ENDOU was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 330 | Severe Asthma | Human | Sputum | SPI1 | Microarray | Genomics | High Throughput | SPI1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 331 | Severe Asthma | Human | Sputum | ZSCAN4 | Microarray | Genomics | High Throughput | ZSCAN4 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 332 | Severe Asthma | Human | Sputum | TRIM8 | Microarray | Genomics | High Throughput | TRIM8 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 333 | Severe Asthma | Human | Sputum | LINC00561 | Microarray | Genomics | High Throughput | LINC00561 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 334 | Severe Asthma | Human | Sputum | TM9SF2 | Microarray | Genomics | High Throughput | TM9SF2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 335 | Severe Asthma | Human | Sputum | CSN3 | Microarray | Genomics | High Throughput | CSN3 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 336 | Severe Asthma | Human | Sputum | RHEB | Microarray | Genomics | High Throughput | RHEB was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 337 | Severe Asthma | Human | Sputum | PRSS58 | Microarray | Genomics | High Throughput | PRSS58 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 338 | Severe Asthma | Human | Sputum | KIAA0319L | Microarray | Genomics | High Throughput | KIAA0319L was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 339 | Severe Asthma | Human | Sputum | IPO11 | Microarray | Genomics | High Throughput | IPO11 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 340 | Severe Asthma | Human | Sputum | LRCH1 | Microarray | Genomics | High Throughput | LRCH1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 341 | Severe Asthma | Human | Sputum | LOC727924 | Microarray | Genomics | High Throughput | LOC727924 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 342 | Severe Asthma | Human | Sputum | LILRA5 | Microarray | Genomics | High Throughput | LILRA5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 343 | Severe Asthma | Human | Sputum | C10ORF126 | Microarray | Genomics | High Throughput | C10ORF126 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 344 | Severe Asthma | Human | Sputum | C11ORF95 | Microarray | Genomics | High Throughput | C11ORF95 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 345 | Severe Asthma | Human | Sputum | ZNF471 | Microarray | Genomics | High Throughput | ZNF471 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 346 | Severe Asthma | Human | Sputum | PLXDC2 | Microarray | Genomics | High Throughput | PLXDC2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 347 | Severe Asthma | Human | Sputum | COL15A1 | Microarray | Genomics | High Throughput | COL15A1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 348 | Severe Asthma | Human | Sputum | TRNAU1AP | Microarray | Genomics | High Throughput | TRNAU1AP was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 349 | Severe Asthma | Human | Sputum | FREM3 | Microarray | Genomics | High Throughput | FREM3 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 350 | Severe Asthma | Human | Sputum | ANKRD33B | Microarray | Genomics | High Throughput | ANKRD33B was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 351 | Severe Asthma | Human | Sputum | IFNA2 | Microarray | Genomics | High Throughput | IFNA2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 352 | Severe Asthma | Human | Sputum | NCF4 | Microarray | Genomics | High Throughput | NCF4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 353 | Severe Asthma | Human | Sputum | L1TD1 | Microarray | Genomics | High Throughput | L1TD1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 354 | Severe Asthma | Human | Sputum | TMEM200B | Microarray | Genomics | High Throughput | TMEM200B was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 355 | Severe Asthma | Human | Sputum | CC2D2B | Microarray | Genomics | High Throughput | CC2D2B was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 356 | Severe Asthma | Human | Sputum | OCIAD2 | Microarray | Genomics | High Throughput | OCIAD2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 357 | Severe Asthma | Human | Sputum | ATP7A | Microarray | Genomics | High Throughput | ATP7A was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 358 | Severe Asthma | Human | Sputum | ST3GAL1 | Microarray | Genomics | High Throughput | ST3GAL1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 359 | Severe Asthma | Human | Sputum | LOC100130964 | Microarray | Genomics | High Throughput | LOC100130964 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 360 | Severe Asthma | Human | Sputum | ZC3H6 | Microarray | Genomics | High Throughput | ZC3H6 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 361 | Severe Asthma | Human | Sputum | LINC00923 | Microarray | Genomics | High Throughput | LINC00923 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 362 | Severe Asthma | Human | Sputum | CSF1R | Microarray | Genomics | High Throughput | CSF1R was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 363 | Severe Asthma | Human | Sputum | OTTHUMG00000177214 | Microarray | Genomics | High Throughput | OTTHUMG00000177214 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 364 | Severe Asthma | Human | Sputum | CCL2 | Microarray | Genomics | High Throughput | CCL2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 365 | Severe Asthma | Human | Sputum | HOXC9 | Microarray | Genomics | High Throughput | HOXC9 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 366 | Severe Asthma | Human | Sputum | LILRB2 | Microarray | Genomics | High Throughput | LILRB2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 367 | Severe Asthma | Human | Sputum | ERC2 | Microarray | Genomics | High Throughput | ERC2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 368 | Severe Asthma | Human | Sputum | PLA2G7 | Microarray | Genomics | High Throughput | PLA2G7 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 369 | Severe Asthma | Human | Sputum | LINC00317 | Microarray | Genomics | High Throughput | LINC00317 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 370 | Severe Asthma | Human | Sputum | HCAR3 | Microarray | Genomics | High Throughput | HCAR3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 371 | Severe Asthma | Human | Sputum | PLA2G4C | Microarray | Genomics | High Throughput | PLA2G4C was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 372 | Severe Asthma | Human | Sputum | CEP57 | Microarray | Genomics | High Throughput | CEP57 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 373 | Severe Asthma | Human | Sputum | DKFZP434J0226 | Microarray | Genomics | High Throughput | DKFZP434J0226 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 374 | Severe Asthma | Human | Sputum | DUSP3 | Microarray | Genomics | High Throughput | DUSP3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 375 | Severe Asthma | Human | Sputum | OTTHUMG00000177665 | Microarray | Genomics | High Throughput | OTTHUMG00000177665 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 376 | Severe Asthma | Human | Sputum | PDE12 | Microarray | Genomics | High Throughput | PDE12 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 377 | Severe Asthma | Human | Sputum | PDZD2 | Microarray | Genomics | High Throughput | PDZD2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 378 | Severe Asthma | Human | Sputum | SH3GLB2 | Microarray | Genomics | High Throughput | SH3GLB2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 379 | Severe Asthma | Human | Sputum | OTTHUMG00000166113 | Microarray | Genomics | High Throughput | OTTHUMG00000166113 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 380 | Severe Asthma | Human | Sputum | UNC50 | Microarray | Genomics | High Throughput | UNC50 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 381 | Severe Asthma | Human | Sputum | TDGF1 | Microarray | Genomics | High Throughput | TDGF1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 382 | Severe Asthma | Human | Sputum | ABCB7 | Microarray | Genomics | High Throughput | ABCB7 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 383 | Severe Asthma | Human | Sputum | LOC100286922 | Microarray | Genomics | High Throughput | LOC100286922 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 384 | Severe Asthma | Human | Sputum | SNHG12 | Microarray | Genomics | High Throughput | SNHG12 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 385 | Severe Asthma | Human | Sputum | LINC00838 | Microarray | Genomics | High Throughput | LINC00838 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 386 | Severe Asthma | Human | Sputum | IL1RN | Microarray | Genomics | High Throughput | IL1RN was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 387 | Severe Asthma | Human | Sputum | OTTHUMG00000031880 | Microarray | Genomics | High Throughput | OTTHUMG00000031880 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 388 | Severe Asthma | Human | Sputum | NPC2 | Microarray | Genomics | High Throughput | NPC2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 389 | Severe Asthma | Human | Sputum | LOC100996694 | Microarray | Genomics | High Throughput | LOC100996694 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 390 | Severe Asthma | Human | Sputum | UGCG | Microarray | Genomics | High Throughput | UGCG was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 391 | Severe Asthma | Human | Sputum | CCDC148-AS1 | Microarray | Genomics | High Throughput | CCDC148-AS1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 392 | Severe Asthma | Human | Sputum | HLA-DPA1 | Microarray | Genomics | High Throughput | HLA-DPA1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 393 | Severe Asthma | Human | Sputum | LINC00564 | Microarray | Genomics | High Throughput | LINC00564 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 394 | Severe Asthma | Human | Sputum | FPR3 | Microarray | Genomics | High Throughput | FPR3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 395 | Severe Asthma | Human | Sputum | MS4A6E | Microarray | Genomics | High Throughput | MS4A6E was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 396 | Severe Asthma | Human | Sputum | PTGER2 | Microarray | Genomics | High Throughput | PTGER2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 397 | Severe Asthma | Human | Sputum | VSTM2A | Microarray | Genomics | High Throughput | VSTM2A was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 398 | Severe Asthma | Human | Sputum | LOC100129518 | Microarray | Genomics | High Throughput | LOC100129518 was significantly up regulated in sputum of severe asthmatics as compared to healthy volunteers. | 28933920 |
| 399 | Severe Asthma | Human | Sputum | BLOC1S2 | Microarray | Genomics | High Throughput | BLOC1S2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 400 | Severe Asthma | Human | Sputum | OTTHUMG00000177005 | Microarray | Genomics | High Throughput | OTTHUMG00000177005 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 401 | Severe Asthma | Human | Sputum | EMP1 | Microarray | Genomics | High Throughput | EMP1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 402 | Severe Asthma | Human | Sputum | IL16 | Microarray | Genomics | High Throughput | IL16 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 403 | Severe Asthma | Human | Sputum | SLC11A1 | Microarray | Genomics | High Throughput | SLC11A1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 404 | Severe Asthma | Human | Sputum | LOC100131392 | Microarray | Genomics | High Throughput | LOC100131392 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 405 | Severe Asthma | Human | Sputum | ARAF | Microarray | Genomics | High Throughput | ARAF was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 406 | Severe Asthma | Human | Sputum | IL12B | Microarray | Genomics | High Throughput | IL12B was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 407 | Severe Asthma | Human | Sputum | SMIM3 | Microarray | Genomics | High Throughput | SMIM3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 408 | Severe Asthma | Human | Sputum | BLID | Microarray | Genomics | High Throughput | BLID was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 409 | Severe Asthma | Human | Sputum | CYSTM1 | Microarray | Genomics | High Throughput | CYSTM1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 410 | Severe Asthma | Human | Sputum | OTTHUMG00000133761 | Microarray | Genomics | High Throughput | OTTHUMG00000133761 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 411 | Severe Asthma | Human | Sputum | GATAD1 | Microarray | Genomics | High Throughput | GATAD1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 412 | Severe Asthma | Human | Sputum | LOC100996511 | Microarray | Genomics | High Throughput | LOC100996511 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 413 | Severe Asthma | Human | Sputum | ANPEP | Microarray | Genomics | High Throughput | ANPEP was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 414 | Severe Asthma | Human | Sputum | LOC285547 | Microarray | Genomics | High Throughput | LOC285547 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 415 | Severe Asthma | Human | Sputum | SAT1 | Microarray | Genomics | High Throughput | SAT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 416 | Severe Asthma | Human | Sputum | LOC400756 | Microarray | Genomics | High Throughput | LOC400756 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 417 | Severe Asthma | Human | Sputum | CLUHP3 | Microarray | Genomics | High Throughput | CLUHP3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 418 | Severe Asthma | Human | Sputum | EARS2 | Microarray | Genomics | High Throughput | EARS2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 419 | Severe Asthma | Human | Sputum | EPB41L3 | Microarray | Genomics | High Throughput | EPB41L3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 420 | Severe Asthma | Human | Sputum | COLGALT2 | Microarray | Genomics | High Throughput | COLGALT2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 421 | Severe Asthma | Human | Sputum | FUNDC2 | Microarray | Genomics | High Throughput | FUNDC2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 422 | Severe Asthma | Human | Sputum | KB-1568E2.1 | Microarray | Genomics | High Throughput | KB-1568E2.1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 423 | Severe Asthma | Human | Sputum | FABP5 | Microarray | Genomics | High Throughput | FABP5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 424 | Severe Asthma | Human | Sputum | NAALADL2-AS3 | Microarray | Genomics | High Throughput | NAALADL2-AS3 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 425 | Severe Asthma | Human | Sputum | FTH1 | Microarray | Genomics | High Throughput | FTH1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 426 | Severe Asthma | Human | Sputum | KCTD20 | Microarray | Genomics | High Throughput | KCTD20 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 427 | Severe Asthma | Human | Sputum | ASB15 | Microarray | Genomics | High Throughput | ASB15 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 428 | Severe Asthma | Human | Sputum | G0S2 | Microarray | Genomics | High Throughput | G0S2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 429 | Severe Asthma | Human | Sputum | OTTHUMG00000031897 | Microarray | Genomics | High Throughput | OTTHUMG00000031897 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 430 | Severe Asthma | Human | Sputum | LOC731424 | Microarray | Genomics | High Throughput | LOC731424 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 431 | Severe Asthma | Human | Sputum | MICU3 | Microarray | Genomics | High Throughput | MICU3 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 432 | Severe Asthma | Human | Sputum | MAFB | Microarray | Genomics | High Throughput | MAFB was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 433 | Severe Asthma | Human | Sputum | C1ORF159 | Microarray | Genomics | High Throughput | C1ORF159 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 434 | Severe Asthma | Human | Sputum | HDGFRP3 | Microarray | Genomics | High Throughput | HDGFRP3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 435 | Severe Asthma | Human | Sputum | LOC100506413 | Microarray | Genomics | High Throughput | LOC100506413 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 436 | Severe Asthma | Human | Sputum | RAB1A | Microarray | Genomics | High Throughput | RAB1A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 437 | Severe Asthma | Human | Sputum | GLUD1P7 | Microarray | Genomics | High Throughput | GLUD1P7 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 438 | Severe Asthma | Human | Sputum | MXD1 | Microarray | Genomics | High Throughput | MXD1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 439 | Severe Asthma | Human | Sputum | AC093391.2 | Microarray | Genomics | High Throughput | AC093391.2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 440 | Severe Asthma | Human | Sputum | HLA-DMA | Microarray | Genomics | High Throughput | HLA-DMA was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 441 | Severe Asthma | Human | Sputum | OR51B4 | Microarray | Genomics | High Throughput | OR51B4 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 442 | Severe Asthma | Human | Sputum | TCP11L1 | Microarray | Genomics | High Throughput | TCP11L1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 443 | Severe Asthma | Human | Sputum | SMIM17 | Microarray | Genomics | High Throughput | SMIM17 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 444 | Severe Asthma | Human | Sputum | IL8 | Microarray | Genomics | High Throughput | IL8 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 445 | Severe Asthma | Human | Sputum | C3ORF36 | Microarray | Genomics | High Throughput | C3ORF36 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 446 | Severe Asthma | Human | Sputum | RNF19B | Microarray | Genomics | High Throughput | RNF19B was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 447 | Severe Asthma | Human | Sputum | CA6 | Microarray | Genomics | High Throughput | CA6 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 448 | Severe Asthma | Human | Sputum | PRKAB1 | Microarray | Genomics | High Throughput | PRKAB1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 449 | Severe Asthma | Human | Sputum | LOC100506388 | Microarray | Genomics | High Throughput | LOC100506388 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 450 | Severe Asthma | Human | Sputum | JUN | Microarray | Genomics | High Throughput | JUN was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 451 | Severe Asthma | Human | Sputum | VASH2 | Microarray | Genomics | High Throughput | VASH2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 452 | Severe Asthma | Human | Sputum | RGCC | Microarray | Genomics | High Throughput | RGCC was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 453 | Severe Asthma | Human | Sputum | TCAM1P | Microarray | Genomics | High Throughput | TCAM1P was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 454 | Severe Asthma | Human | Sputum | SLC39A14 | Microarray | Genomics | High Throughput | SLC39A14 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 455 | Severe Asthma | Human | Sputum | SLC7A13 | Microarray | Genomics | High Throughput | SLC7A13 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 456 | Severe Asthma | Human | Sputum | RIPK2 | Microarray | Genomics | High Throughput | RIPK2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 457 | Severe Asthma | Human | Sputum | OTTHUMG00000172365 | Microarray | Genomics | High Throughput | OTTHUMG00000172365 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 458 | Severe Asthma | Human | Sputum | DHX40 | Microarray | Genomics | High Throughput | DHX40 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 459 | Severe Asthma | Human | Sputum | CCT8L2 | Microarray | Genomics | High Throughput | CCT8L2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 460 | Severe Asthma | Human | Sputum | SLC7A7 | Microarray | Genomics | High Throughput | SLC7A7 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 461 | Severe Asthma | Human | Sputum | ADAM11 | Microarray | Genomics | High Throughput | ADAM11 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 462 | Severe Asthma | Human | Sputum | RHOB | Microarray | Genomics | High Throughput | RHOB was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 463 | Severe Asthma | Human | Sputum | LOC100505817 | Microarray | Genomics | High Throughput | LOC100505817 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 464 | Severe Asthma | Human | Sputum | MICU2 | Microarray | Genomics | High Throughput | MICU2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 465 | Severe Asthma | Human | Sputum | SLC6A15 | Microarray | Genomics | High Throughput | SLC6A15 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 466 | Severe Asthma | Human | Sputum | LGALS3 | Microarray | Genomics | High Throughput | LGALS3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 467 | Severe Asthma | Human | Sputum | CTD-2561B21.11 | Microarray | Genomics | High Throughput | CTD-2561B21.11 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 468 | Severe Asthma | Human | Sputum | ATG5 | Microarray | Genomics | High Throughput | ATG5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 469 | Severe Asthma | Human | Sputum | IFNA21 | Microarray | Genomics | High Throughput | IFNA21 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 470 | Severe Asthma | Human | Sputum | RIT1 | Microarray | Genomics | High Throughput | RIT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 471 | Severe Asthma | Human | Sputum | GALNT13 | Microarray | Genomics | High Throughput | GALNT13 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 472 | Severe Asthma | Human | Sputum | CD83 | Microarray | Genomics | High Throughput | CD83 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 473 | Severe Asthma | Human | Sputum | SRY | Microarray | Genomics | High Throughput | SRY was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 474 | Severe Asthma | Human | Sputum | MXI1 | Microarray | Genomics | High Throughput | MXI1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 475 | Severe Asthma | Human | Sputum | LINC00260 | Microarray | Genomics | High Throughput | LINC00260 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 476 | Severe Asthma | Human | Sputum | ZNF638 | Microarray | Genomics | High Throughput | ZNF638 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 477 | Severe Asthma | Human | Sputum | RSPO2 | Microarray | Genomics | High Throughput | RSPO2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 478 | Severe Asthma | Human | Sputum | SMDT1 | Microarray | Genomics | High Throughput | SMDT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 479 | Severe Asthma | Human | Sputum | RPTN | Microarray | Genomics | High Throughput | RPTN was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 480 | Severe Asthma | Human | Sputum | MARCKS | Microarray | Genomics | High Throughput | MARCKS was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 481 | Severe Asthma | Human | Sputum | HTR1D | Microarray | Genomics | High Throughput | HTR1D was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 482 | Severe Asthma | Human | Sputum | TM2D1 | Microarray | Genomics | High Throughput | TM2D1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 483 | Severe Asthma | Human | Sputum | OTTHUMG00000175668 | Microarray | Genomics | High Throughput | OTTHUMG00000175668 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 484 | Severe Asthma | Human | Sputum | MS4A4A | Microarray | Genomics | High Throughput | MS4A4A was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 485 | Severe Asthma | Human | Sputum | FSD2 | Microarray | Genomics | High Throughput | FSD2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 486 | Severe Asthma | Human | Sputum | FLOT1 | Microarray | Genomics | High Throughput | FLOT1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 487 | Severe Asthma | Human | Sputum | LINC00314 | Microarray | Genomics | High Throughput | LINC00314 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 488 | Severe Asthma | Human | Sputum | ANKRD34C | Microarray | Genomics | High Throughput | ANKRD34C was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 489 | Severe Asthma | Human | Sputum | EZH2 | Microarray | Genomics | High Throughput | EZH2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 490 | Severe Asthma | Human | Sputum | KRT8P17 | Microarray | Genomics | High Throughput | KRT8P17 was significantly down regulated in sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 491 | Severe Asthma | Human | Sputum | KLHL24 | Microarray | Genomics | High Throughput | KLHL24 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 492 | Severe Asthma | Human | Sputum | KCNH8 | Microarray | Genomics | High Throughput | KCNH8 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 493 | Severe Asthma | Human | Sputum | HAVCR2 | Microarray | Genomics | High Throughput | HAVCR2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 494 | Severe Asthma | Human | Sputum | PSG6 | Microarray | Genomics | High Throughput | PSG6 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 495 | Severe Asthma | Human | Sputum | KRTAP4-1 | Microarray | Genomics | High Throughput | KRTAP4-1 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 496 | Severe Asthma | Human | Sputum | AREG | Microarray | Genomics | High Throughput | AREG was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 497 | Severe Asthma | Human | Sputum | ST6GAL2 | Microarray | Genomics | High Throughput | ST6GAL2 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 498 | Severe Asthma | Human | Sputum | SLC7A5 | Microarray | Genomics | High Throughput | SLC7A5 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 499 | Severe Asthma | Human | Sputum | NPVF | Microarray | Genomics | High Throughput | NPVF was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 500 | Severe Asthma | Human | Sputum | NEDD9 | Microarray | Genomics | High Throughput | NEDD9 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 501 | Severe Asthma | Human | Sputum | MCM3AP | Microarray | Genomics | High Throughput | MCM3AP was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 502 | Severe Asthma | Human | Sputum | B3GNT2 | Microarray | Genomics | High Throughput | B3GNT2 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 503 | Severe Asthma | Human | Sputum | PP12708 | Microarray | Genomics | High Throughput | PP12708 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 504 | Severe Asthma | Human | Sputum | RREB1 | Microarray | Genomics | High Throughput | RREB1 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 505 | Severe Asthma | Human | Sputum | OR7A5 | Microarray | Genomics | High Throughput | OR7A5 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 506 | Severe Asthma | Human | Sputum | KLF4 | Microarray | Genomics | High Throughput | KLF4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 507 | Severe Asthma | Human | Sputum | KRT33B | Microarray | Genomics | High Throughput | KRT33B was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 508 | Severe Asthma | Human | Sputum | KLF10 | Microarray | Genomics | High Throughput | KLF10 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 509 | Severe Asthma | Human | Sputum | METTL2B | Microarray | Genomics | High Throughput | METTL2B was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 510 | Severe Asthma | Human | Sputum | HSPA6 | Microarray | Genomics | High Throughput | HSPA6 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 511 | Severe Asthma | Human | Sputum | C16ORF78 | Microarray | Genomics | High Throughput | C16ORF78 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 512 | Severe Asthma | Human | Sputum | CCL3 | Microarray | Genomics | High Throughput | CCL3 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 513 | Severe Asthma | Human | Sputum | C17ORF78 | Microarray | Genomics | High Throughput | C17ORF78 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 514 | Severe Asthma | Human | Sputum | ST8SIA4 | Microarray | Genomics | High Throughput | ST8SIA4 was significantly up regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 515 | Severe Asthma | Human | Sputum | OTTHUMG00000175907 | Microarray | Genomics | High Throughput | OTTHUMG00000175907 was significantly down regulated in the sputum of severe asthmatics as compared to healthy subjects. | 28933920 |
| 516 | Severe Refractory Asthma (SRA) | Human | Induced Sputum | VEGF | ELISA | Others | Low Throughput | Exhaled Breath Temperature (EBT) was significantly associated with VEGF levels in sputum supernatant from SRA patients. EBT was significantly higher in patients with SRA compared to those with mild to moderate asthma. | 29176061 |
| 517 | Asthma, COPD | Human | Serum, Induced Sputum | IL6 | ELISA | Others | Low Throughput | In the COPD group, serum and induced sputum IL6 concentrations were statistically higher than in the asthma group. | 29319364 |
| 518 | Mild-to moderate/Severe Asthma and Cough Variant Asthma (CVA) | Human | Induced Sputum | IL25 | qRT-PCR, ELISA | Genomics, Others | Low Throughput | A lower IL25 mRNA expression in sputum cells was observed in severe asthma compared to CVA and controls. IL25 protein concentration in sputum supernatants was elevated in patients with severe asthma compared to controls, CVA and mild-to-moderate asthma. Sputum IL25 level was increased in atopic versus non-atopic asthma patients. The elevated IL25 mRNA expression and protein concentration was associated with a lower eosinophil and higher neutrophil percentage in asthmatic airways. | 30429702 |
| 519 | Bronchial Asthma | Human | Sputum | SERPINB2 | qRT-PCR | Genomics | Low Throughput | SERPINB2 gene expression in asthma group was increased than that from healthy control. The highest increase of SERPINB2 expression was found in severe asthma as compared to the mild asthma group. The expression level of SERPINB2 gene was significantly correlated with the severity of bronchial asthma. | 29120588 |
| 520 | Childhood Allergic Asthma | Human | Peripheral Blood, Induced Sputum | IDO | High Performance Liquid Chromatography (HPLC) | Others | Low Throughput | The IDO levels in the peripheral blood and induced sputum were significantly lower in patients with childhood allergic asthma than in children in the control group. The IDO level was negatively correlated with FeNO. | 29150070 |
| 521 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Peripheral Blood Mononuclear Cells (PBMCs), Blood Plasma, Sputum | RIGI | Flow Cytometry | Others | Low Throughput | At exacerbation, the RIGI expression was higher in classical Dendritic Cells and peripheral Dendritic Cells but not in monocytes from asthma patients with viral infection both at steady state and exacerbation (V+V+) than in patients with viral infection at exacerbation only (V+V-). | 29137638 |
| 522 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | IL5 | ELISA | Others | Low Throughput | Virus infected asthma patients had significantly higher IL5 levels in sputum and plasma than in asthma patients without any viral infection. These levels were associated with higher percentages of sputum eosinophils. Sputum IL5 concentrations were lower in asthma patients with viral infection at both steady and exacerbation state (V+V+) than in patients with viral infection at exacerbation only (V+V-) at both periods. | 29137638 |
| 523 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | CXCL8 | ELISA | Others | Low Throughput | Compared to steady state, CXCL8 level in the sputum of virus infected asthmatic patients were significantly higher during exacerbation. | 29137638 |
| 524 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Peripheral Blood Mononuclear Cells (PBMCs), Blood Plasma, Sputum | TLR3 | Flow Cytometry | Others | Low Throughput | At exacerbation and steady state, classical Dendritic Cells and monocytes in asthma patients with viral infection both at steady state and exacerbation (V+V+), expressed significantly more TLR3 than that in patients with viral infection at exacerbation only (V+V-). | 29137638 |
| 525 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | IL22 | ELISA | Others | Low Throughput | Plasma IL22 levels were significantly lower in virus infected asthma patients at steady state. Higher IL22 levels were detected in sputum of asthma patients with viral infection both at steady state and exacerbation (V+V+) at steady state. | 29137638 |
| 526 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Peripheral Blood Mononuclear Cells (PBMCs), Blood Plasma, Sputum | IL1B | ELISA | Others | Low Throughput | Compared to Virus uninfected asthma patients, IL1B was increased in unstimulated PBMC of Virus infected asthma patients. During exacerbation and at steady state, sputum concentrations of IL1B were higher in asthma patients with viral infection at both steady and exacerbation state (V+V+) than in patients with viral infection at exacerbation only (V+V-). | 29137638 |
| 527 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | IFNG | ELISA | Others | Low Throughput | Compared to asthma patients with viral infection at exacerbation only (V+V-), sputum IFNG levels at exacerbation were lower in asthma patients with viral infection both at steady state and exacerbation (V+V+). In plasma, IFNG levels were lower in V+V+. | 29137638 |
| 528 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | IL6 | ELISA | Others | Low Throughput | Compared to steady state, IL6 level in the sputum of virus infected asthmatic patients were significantly higher during exacerbation. Plasma IL6 concentrations were greater in asthma patients with viral infection both at steady state and exacerbation (V+V+) than in patients with viral infection at exacerbation only (V+V-) during exacerbation. | 29137638 |
| 529 | Allergic Asthma (Virus triggered exacerbation in allergic asthma children) | Human | Blood Plasma, Sputum | IL29 | ELISA | Others | Low Throughput | In plasma, IL29 levels were greater in asthma patients with viral infection both at steady state and exacerbation (V+V+). | 29137638 |
| 530 | Asthma | Human | Induced Sputum, Serum | PlGF | ELISA | Others | Low Throughput | Significantly higher serum and sputum PlGF levels were noted in asthma patients, especially asthmatic smokers, than in healthy controls. Serum and sputum PlGF levels correlated negatively with post-bronchodilator forced expiratory volume in 1s (FEV1) and the FEV1/forced vital capacity, but positively with airway-wall thickening. | 28220848 |
| 531 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | ITPR3 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | ITPR3 was increased in male asthmatics. Such increase was not observed in females highlighting sexual dimorphism in asthma. | 31095684 |
| 532 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | ALOX15 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | ALOX15 was increased in male asthmatics. Such increase was not observed in females highlighting sexual dimorphism in asthma. | 31095684 |
| 533 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | FBXL7 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | FBXL7 was increased in male asthmatics. Such increase was not observed in females highlighting sexual dimorphism in asthma. | 31095684 |
| 534 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | RAD51B | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | RAD51B was decreased in male asthmatics. Such decrease was not observed in females highlighting sexual dimorphism in asthma. | 31095684 |
| 535 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | HLA-DQA1 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | HLA-DQA1 was decreased in female asthmatics. Such decrease was not observed in males highlighting sexual dimorphism in asthma. | 31095684 |
| 536 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | CCR6 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | CCR6 was decreased in both male and female asthmatics. | 31095684 |
| 537 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | CXCR7 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | CXCR7 was decreased in both male and female asthmatics. | 31095684 |
| 538 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | CCL26 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | CCL26 was decreased in female asthmatics but increased in male asthmatics. | 31095684 |
| 539 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | JAK2 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | JAK2 was increased in female asthmatics. | 31095684 |
| 540 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | SDC2 | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | SDC2 was decreased in female asthmatics but increased in male asthmatics. | 31095684 |
| 541 | Asthma | Human | Epithelial cells, Whole Blood, T cells, Induced Sputum, Lymphoblastoid Cell line | HLA-DMB | Gene Expression Analysis, Genome wide Analysis | Genomics, Bioinformatics | High Throughput | HLA-DMB was decreased in both male and female asthmatics. | 31095684 |
| 542 | Severe Asthma | Human | Sputum | IL6R | Microarray (Data analysis) | Transcriptomics | High Throughput | A subset of severe asthma patients has increased IL6R mRNA levels in the sputum. This sub-population is highly neutrophilic and has poorer lung function. This group had higher levels of systemic IL6 and CRP levels. | 29315928 |
| 543 | Severe Asthma | Human | Sputum | IL6 | SomaScan platform (Data analysis) | Proteomics | High Throughput | A subset of severe asthma patients has increased IL6 protein levels in the sputum. This sub-population is highly neutrophilic and has poorer lung function. | 29315928 |
| 544 | Asthma | Human | Sputum | IL1R1 | qRT-PCR | Genomics | Low Throughput | Sputum cell IL1R1 expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. Higher expression levels of IL1R1 was associated with reduced FEV1/forced vital capacity ratio. | 29103994 |
| 545 | Asthma | Human | Sputum | IL1RAP | qRT-PCR | Genomics | Low Throughput | Sputum cell IL1RAP expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. Higher expression levels of IL1RAP was associated with reduced FEV1/forced vital capacity ratio. | 29103994 |
| 546 | Asthma | Human | Sputum | IL4R | qRT-PCR | Genomics | Low Throughput | Sputum cell IL4R expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. Higher expression levels of IL4R was associated with reduced FEV1/forced vital capacity ratio. | 29103994 |
| 547 | Pediatric Asthma | Human | Serum, Sputum | ALCAM | ELISA | Others | Low Throughput | ALCAM levels were higher in children with asthma than in normal control subjects. Serum and sputum ALCAM levels were higher in children with more severe asthma and serum ALCAM levels were inversely correlated with PC20 in asthma patients. ALCAM can be a potential therapeutic target for allergic asthma. | 29394080 |
| 548 | Pediatric Asthma | Human | Sputum | CHIT1 | ELISA | Others | Low Throughput | The levels of sputum CHIT1 were significantly increased in the patients with childhood asthma as compared to control subjects. | 29420850 |
| 549 | Allergic Asthma | Human | Bone marrow, Peripheral Blood, Sputum | IL17RB | Flow Cytometry | Others | Low Throughput | There were increased percentage of basophils expressing IL-17RB collected from bone marrow, peripheral blood, and sputum after allergen inhalation challenge. | 26762527 |
| 550 | Allergic Asthma | Human | Bone marrow, Peripheral Blood, Sputum | ST2 | Flow Cytometry | Others | Low Throughput | There were increased percentage of basophils expressing ST2 collected from bone marrow, peripheral blood, and sputum after allergen inhalation challenge. | 26762527 |
| 551 | Allergic Asthma | Human | Bone marrow, Peripheral Blood, Sputum | IL25 | Flow Cytometry | Others | Low Throughput | There were increased intracellular IL-25 collected from bone marrow, peripheral blood and sputum after allergen inhalation challenge. IL25 increase basophil activation and migratory potential, and may pose as a novel therapeutic target for the treatment of allergic asthma. | 26762527 |
| 552 | Asthma | Human | Induced Sputum | IFNG | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased IFNG as compared to the mild asthma group. | 29520864 |
| 553 | Asthma | Human | Induced Sputum | PDGFBB | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased PDGFBB as compared to the mild asthma group. | 29520864 |
| 554 | Asthma | Human | Induced Sputum | FLT3L | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased Fit3L as compared to the mild asthma group. | 29520864 |
| 555 | Asthma | Human | Induced Sputum | IL2 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased IL2 as compared to the mild asthma group. | 29520864 |
| 556 | Asthma | Human | Induced Sputum | IL4 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased IL4 as compared to the mild asthma group. | 29520864 |
| 557 | Asthma | Human | Induced Sputum | IL9 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased IL9 as compared to the mild asthma group. | 29520864 |
| 558 | Asthma | Human | Induced Sputum | TNFbeta | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased TNFbeta as compared to the mild asthma group. | 29520864 |
| 559 | Asthma | Human | Induced Sputum | CCL27 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased CCL27 as compared to the mild asthma group. | 29520864 |
| 560 | Asthma | Human | Induced Sputum | CXCL7 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had increased CXCL7 as compared to the mild asthma group. | 29520864 |
| 561 | Asthma | Human | Induced Sputum | IL3 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had decreased IL3 as compared to the mild asthma group. | 29520864 |
| 562 | Asthma | Human | Induced Sputum | CXCL10 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had decreased CXCL10 as compared to the mild asthma group. | 29520864 |
| 563 | Asthma | Human | Induced Sputum | CXCL11 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had decreased CXCL11 as compared to the mild asthma group. | 29520864 |
| 564 | Asthma | Human | Induced Sputum | CXCL13 | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group had decreased CXCL13 as compared to the mild asthma group. | 29520864 |
| 565 | Asthma | Human | Induced Sputum | VEGF | Milliplex Human Cytokine/Chemokine panel | Others | High Throughput | The severe asthma group showed a decreasing trend of VEGF as compared to the mild asthma group. | 29520864 |
| 566 | Asthma | Human | Bronchial Brushings, Induced Sputum, Blood Plasma | miR-221-3p | qRT-PCR | Genomics | Low Throughput | Epithelial, sputum, and plasma miR-221-3p expression was significantly decreased in subjects with asthma. Decreased epithelial miR-221-3p may protect against airway eosinophilic inflammation by upregulating anti-inflammatory chemokine CXCL17. | 29644894 |
| 567 | Noneosinophilic Childhood Asthma | Human | Induced Sputum | TWEAK | ELISA | Others | Low Throughput | Sputum TWEAK level was significantly elevated in children with asthma than in healthy controls. It was significantly higher in patients with severe asthma than in those with mild to moderate asthma. Sputum TWEAK level showed significant positive correlation with asthma severity and a negative correlation with FeNO. | 29068159 |
| 568 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL13 | Microarray | Genomics | High Throughput | IL13 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 569 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL5 | Microarray | Genomics | High Throughput | IL5 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 570 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL4 | Microarray | Genomics | High Throughput | Il4 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 571 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL9 | Microarray | Genomics | High Throughput | IL9 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 572 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CCR2 | Microarray | Genomics | High Throughput | CCR2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. CCR2 was negatively correlated with FEV1. | 27421833 |
| 573 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CCL26 | Microarray | Genomics | High Throughput | CCL26 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 574 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CCL17 | Microarray | Genomics | High Throughput | CCL17 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 575 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CCL13 | Microarray | Genomics | High Throughput | CCL13 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 576 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | GGT5 | Microarray | Genomics | High Throughput | GGT5 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 577 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | PTGS1 | Microarray | Genomics | High Throughput | PTGS1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 578 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | ALOX15 | Microarray | Genomics | High Throughput | ALOX15 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 579 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | HDC | Microarray | Genomics | High Throughput | HDC gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 580 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | HRH4 | Microarray | Genomics | High Throughput | HRH4 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 581 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | FCER1A | Microarray | Genomics | High Throughput | FCER1A gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 582 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | PTGER3 | Microarray | Genomics | High Throughput | PTGER3 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 583 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | FCER2 | Microarray | Genomics | High Throughput | FCER2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 584 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD1A | Microarray | Genomics | High Throughput | CD1A gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 585 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD209 | Microarray | Genomics | High Throughput | CD209 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 586 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD200R1 | Microarray | Genomics | High Throughput | CD200R1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 587 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD1B | Microarray | Genomics | High Throughput | CD1B gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 588 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD207 | Microarray | Genomics | High Throughput | CD207 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 589 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CD1C | Microarray | Genomics | High Throughput | CD1C gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. CD1C was negatively correlated with FEV1. | 27421833 |
| 590 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL32 | Microarray | Genomics | High Throughput | IL32 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 591 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | TNFRSF4 | Microarray | Genomics | High Throughput | TNFRSF4 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 592 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | NRG1 | Microarray | Genomics | High Throughput | NRG1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. NRG1 was negatively correlated with FEV1. | 27421833 |
| 593 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | TNFRSF10D | Microarray | Genomics | High Throughput | TNFRSF10D gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 594 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CRLF2 | Microarray | Genomics | High Throughput | CRLF2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 595 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | FLT3 | Microarray | Genomics | High Throughput | FLT3 was negatively correlated with FEV1 measurements. | 27421833 |
| 596 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL1RL1 | Microarray | Genomics | High Throughput | IL1RL1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 597 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | GPR171 | Microarray | Genomics | High Throughput | GPR171 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 598 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IL26 | Microarray | Genomics | High Throughput | IL26 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. IL26 was negatively correlated with FEV1. | 27421833 |
| 599 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | P2RY6 | Microarray | Genomics | High Throughput | P2RY6 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 600 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | ADAM19 | Microarray | Genomics | High Throughput | ADAM19 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 601 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | MMP1 | Microarray | Genomics | High Throughput | MMP1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 602 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | MAP2K6 | Microarray | Genomics | High Throughput | MAP2K6 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. MAP2K6 was negatively correlated with FEV1. | 27421833 |
| 603 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | MAOA | Microarray | Genomics | High Throughput | MAOA gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 604 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | GZMB | Microarray | Genomics | High Throughput | GZMB gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 605 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | CISH | Microarray | Genomics | High Throughput | CISH gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 606 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | SOCS2 | Microarray | Genomics | High Throughput | SOCS2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 607 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | SOCS1 | Microarray | Genomics | High Throughput | SOCS1 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 608 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | NFATC2 | Microarray | Genomics | High Throughput | NFATC2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 609 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | VDR | Microarray | Genomics | High Throughput | VDR gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 610 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | IRF4 | Microarray | Genomics | High Throughput | IRF4 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 611 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | RUNX3 | Microarray | Genomics | High Throughput | RUNX3 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. RUNX3 was negatively correlated with FEV1. | 27421833 |
| 612 | Allergic Asthma (following allergen bronchoprovocation test with HDM) | Human | Induced Sputum | GATA2 | Microarray | Genomics | High Throughput | GATA2 gene expression was up regulated by allergen challenge and was down regulated by fluticasone treatment. | 27421833 |
| 613 | Asthma | Human | Induced Sputum Cells | ST2L | FACS, qRT-pCR | Others, Genomics | Low Throughput | ST2L expression was markedly increased in asthmatics as compared to healthy subjects. | 27432971 |
| 614 | Asthma | Human | Sputum | CD80 | Flow Cytometry | Others | Low Throughput | CD80 expression was significantly increased in stable asthmatics and during asthma exacerbations as compared to healthy controls. | 29054692 |
| 615 | Asthma | Human | Sputum | CD86 | Flow Cytometry | Others | Low Throughput | CD86 expression was significantly increased in stable asthmatics and during asthma exacerbations as compared to healthy controls. | 29054692 |
| 616 | Asthma | Human | Sputum | PDL1 | Flow Cytometry | Others | Low Throughput | PDL1 expression was significantly increased in stable asthmatics and during asthma exacerbations as compared to healthy controls. | 29054692 |
| 617 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | IGLV1-47 | LC-IMS-MS | Proteomics | High Throughput | IGLV1-47 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 618 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | AACT | LC-IMS-MS | Proteomics | High Throughput | AACT expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 619 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | AGP1 | LC-IMS-MS | Proteomics | High Throughput | AGP1 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 620 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | IGLC2 | LC-IMS-MS | Proteomics | High Throughput | IGLC2 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 621 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | SERPING1 | LC-IMS-MS | Proteomics | High Throughput | SERPING1 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 622 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | LTF | LC-IMS-MS | Proteomics | High Throughput | LTF expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 623 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | LCN1 | LC-IMS-MS | Proteomics | High Throughput | LCN1 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 624 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | TF | LC-IMS-MS | Proteomics | High Throughput | TF expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 625 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | KRT6B | LC-IMS-MS | Proteomics | High Throughput | KRT6B expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 626 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | KRT10 | LC-IMS-MS | Proteomics | High Throughput | KRT10 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 627 | Severe Asthma with Gastro-Oesophageal Reflux (GORD) | Human | Sputum | HSPA8 | LC-IMS-MS | Proteomics | High Throughput | HSPA8 expression was significantly differentially expressed in active GORD as compared to no GORD. | 30961953 |
| 628 | Asthma | Human | Sputum | CLC | qRT-PCR | Genomics | Low Throughput | CLC is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 629 | Asthma | Human | Sputum | IL1B | qRT-PCR | Genomics | Low Throughput | IL1B is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 630 | Asthma | Human | Sputum | CPA3 | qRT-PCR | Genomics | Low Throughput | CPA3 is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 631 | Asthma | Human | Sputum | ALPL | qRT-PCR | Genomics | Low Throughput | ALPL is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 632 | Asthma | Human | Sputum | DNASE1L3 | qRT-PCR | Genomics | Low Throughput | DNASE1L3 is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 633 | Asthma | Human | Sputum | CXCR2 | qRT-PCR | Genomics | Low Throughput | CXCR2 is a sputum gene signature that can predict future exacerbation phenotypes of asthma, with the greatest biomarker performance in identifying those who would experience frequent severe exacerbations. | 30682452 |
| 634 | Asthma, COPD | Human | Serum, Sputum | IL4 | ELISA | Others | Low Throughput | Serum and sputum levels of IL4 was significantly increased in the COPD patient group as compared to asthma group. | 30908476 |
| 635 | Asthma, COPD | Human | Serum, Sputum | IL5 | ELISA | Others | Low Throughput | Serum and sputum levels of IL5 was significantly increased in the COPD patient group as compared to asthma group. | 30908476 |
| 636 | Asthma, COPD | Human | Serum, Sputum | IL9 | ELISA | Others | Low Throughput | Serum and sputum levels of IL9 was significantly increased in the COPD patient group as compared to asthma group. | 30908476 |
| 637 | Asthma, COPD | Human | Serum, Sputum | IL13 | ELISA | Others | Low Throughput | Serum and sputum levels of IL13 was significantly increased in the COPD patient group as compared to asthma group. | 30908476 |
| 638 | Asthma, COPD | Human | Serum, Sputum | IL6 | ELISA | Others | Low Throughput | Serum and sputum levels of IL6 was significantly increased in the bronchial asthma patient group as compared to COPD subjects. | 30908476 |
| 639 | Asthma, COPD | Human | Serum, Sputum | IL1B | ELISA | Others | Low Throughput | Serum and sputum levels of IL1B was significantly increased in the bronchial asthma patient group as compared to COPD subjects. | 30908476 |
| 640 | Asthma, COPD | Human | Serum, Sputum | TNFalpha | ELISA | Others | Low Throughput | Serum and sputum levels of TNFalpha was significantly increased in the bronchial asthma patient group as compared to COPD subjects. | 30908476 |
| 641 | Asthma | Human | Sputum | IL13 | Microarray | Genomics | High Throughput | Asthma patients of an eosinophilic and highly atopic phenotype patients had increased blood IL13 levels, while those of neutrophilic phenotype had reduced IL13 expression. | 30928653 |
| 642 | Asthma | Human | Sputum | HP | Mass Spectrometry | Proteomics | High Throughput | Asthma patients of an eosinophilic phenotype patients had increased sputum haptoglobin levels. | 30928653 |
| 643 | Asthma | Human | Sputum | SCGB1A1 | Mass Spectrometry | Proteomics | High Throughput | Asthma patients of the highly atopic phenotype had high levels of sputum uteroglobin. | 30928653 |
| 644 | Asthma | Human | Sputum | CLU | Mass Spectrometry | Proteomics | High Throughput | Asthma patients of the highly atopic phenotype had high levels of sputum clusterin protein. Differences in sputum clusterin level was found to aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 645 | Asthma | Human | Sputum | S100A9 | Mass Spectrometry | Proteomics | High Throughput | Asthma patients of the neutrophilic subphenotypes had greater concentrations of sputum S100A9. | 30928653 |
| 646 | Asthma | Human | Sputum | MMP9 | Mass Spectrometry | Proteomics | High Throughput | Asthma patients of the neutrophilic subphenotypes had greater concentrations of sputum matrix metalloproteinase 9 (MMP9). | 30928653 |
| 647 | Asthma | Human | Sputum | H4C | Mass Spectrometry | Proteomics | High Throughput | Histone H4 was up regulated in eosinophilic and neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic and neutrophilic phenotype. | 30928653 |
| 648 | Asthma | Human | Sputum | VTN | Mass Spectrometry | Proteomics | High Throughput | Vitronectin was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 649 | Asthma | Human | Sputum | HRG | Mass Spectrometry | Proteomics | High Throughput | Histidine-rich glycoprotein was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 650 | Asthma | Human | Sputum | IGHG3 | Mass Spectrometry | Proteomics | High Throughput | Immunoglobulin heavy constant gamma3 was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 651 | Asthma | Human | Sputum | EZR | Mass Spectrometry | Proteomics | High Throughput | Ezrin was down regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 652 | Asthma | Human | Sputum | C3 | Mass Spectrometry | Proteomics | High Throughput | Complement C3 was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 653 | Asthma | Human | Sputum | TTR | Mass Spectrometry | Proteomics | High Throughput | Transthyretin was up regulated in eosinophilic phenotype but down regulated in neutrophilic asthma as compared with that of the other cohort. It is strongly predictive of the eosinophilic and the neutrophilic phenotype. | 30928653 |
| 654 | Asthma | Human | Sputum | TF | Mass Spectrometry | Proteomics | High Throughput | Serotransferrin was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. | 30928653 |
| 655 | Asthma | Human | Sputum | SERPINA1 | Mass Spectrometry | Proteomics | High Throughput | A-1-antitrypsin was up regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. Differences in sputum SERPINA1 level was found to aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 656 | Asthma | Human | Sputum | LGALS3BP | Mass Spectrometry | Proteomics | High Throughput | Galectin-3–binding protein was down regulated in eosinophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire eosinophilic phenotype. Differences in sputum LGALS3BP level was found to aid in distinguishing between the subphenotypes within the eosinophilic and neutrophilic phenotype of asthma. | 30928653 |
| 657 | Asthma | Human | Sputum | AZU1 | Mass Spectrometry | Proteomics | High Throughput | Azurocidin was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. | 30928653 |
| 658 | Asthma | Human | Sputum | CORO1A | Mass Spectrometry | Proteomics | High Throughput | Coronin-1A was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. | 30928653 |
| 659 | Asthma | Human | Sputum | CLIC1 | Mass Spectrometry | Proteomics | High Throughput | Chloride intracellular channel protein 1 was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. | 30928653 |
| 660 | Asthma | Human | Sputum | ANXA1 | Mass Spectrometry | Proteomics | High Throughput | Annexin A1 was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. | 30928653 |
| 661 | Asthma | Human | Sputum | ANXA3 | Mass Spectrometry | Proteomics | High Throughput | Annexin A3 was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. | 30928653 |
| 662 | Asthma | Human | Sputum | LCN2 | Mass Spectrometry | Proteomics | High Throughput | Neutrophil gelatinase associated lipocalin was up regulated in neutrophilic phenotype as compared with that of the other cohort. It is strongly predictive of the entire neutrophilic phenotype. Differences in sputum LCN2 level was found to aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 663 | Asthma | Human | Sputum | MSN | Mass Spectrometry | Proteomics | High Throughput | Moesin was down regulated in highly atopic phenotype as compared with that of the other cohort. | 30928653 |
| 664 | Asthma | Human | Sputum | LCP1 | Mass Spectrometry | Proteomics | High Throughput | Plastin2 was down regulated in highly atopic phenotype as compared with that of the other cohort. | 30928653 |
| 665 | Asthma | Human | Sputum | HPX | Mass Spectrometry | Proteomics | High Throughput | Hemopexin was down regulated in highly atopic phenotype as compared with that of the other cohort. Differences in sputum HPX level was found to aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 666 | Asthma | Human | Sputum | CST3 | Mass Spectrometry | Proteomics | High Throughput | Cystatin C was up regulated in highly atopic phenotype as compared with that of the other cohort. | 30928653 |
| 667 | Asthma | Human | Sputum | CFL1 | Mass Spectrometry | Proteomics | High Throughput | Cofilin1 was down regulated in highly atopic phenotype as compared with that of the other cohort. | 30928653 |
| 668 | Asthma | Human | Sputum | ACTB | Mass Spectrometry | Proteomics | High Throughput | Actin, cytoplasmic 1 was down regulated in highly atopic phenotype as compared with that of the other cohort. | 30928653 |
| 669 | Asthma | Human | Sputum | SERPINB1 | Mass Spectrometry | Proteomics | High Throughput | Leukocyte elastase inhibitor was down regulated in highly atopic phenotype as compared with that of the other cohort. Differences in sputum SERPINB1 level was found to aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 670 | Asthma | Human | Sputum | BPIFB2 | Mass Spectrometry | Proteomics | High Throughput | BPI fold containing family B member 1 was up regulated in highly atopic phenotype as compared with that of the other cohort. Differences in sputum BPIFB2 level was found to aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 671 | Asthma | Human | Sputum | GAPDH | Mass Spectrometry | Proteomics | High Throughput | Glyceraldehyde 3 phosphate dehydrogenase was down regulated in highly atopic phenotype as compared with that of the other cohort. Differences in sputum GAPDH level was found to aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 672 | Asthma | Human | Sputum | COL18A1 | Microarray | Transcriptomics | High Throughput | COL18A1 was up regulated in highly atopic asthmatics but was down regulated in eosinophilic and neutrophilic asthma. | 30928653 |
| 673 | Asthma | Human | Sputum | IFNG | Microarray | Transcriptomics | High Throughput | IFNG level was up regulated in asthmatics belonging to the neutrophilic phenotype. | 30928653 |
| 674 | Asthma | Human | Sputum | IFNA | Microarray | Transcriptomics | High Throughput | IFNA level was up regulated in asthmatics belonging to the eosinophilic and neutrophilic phenotype, but was down regulated in highly atopic phenotype. | 30928653 |
| 675 | Asthma | Human | Sputum | IL4 | Microarray | Transcriptomics | High Throughput | IL4 level was up regulated in asthmatics belonging to the eosinophilic phenotype. | 30928653 |
| 676 | Asthma | Human | Sputum | RARα | Microarray | Transcriptomics | High Throughput | RARα level was up regulated in asthmatics belonging to the eosinophilic phenotype but was down regulated in neutrophilic and highly atopic asthmatics. | 30928653 |
| 677 | Asthma | Human | Sputum | IL2 | Microarray | Transcriptomics | High Throughput | IL2 level was up regulated in asthmatics belonging to the eosinophilic and neutrophilic phenotype, but down regulated in highly atopic asthmatics. | 30928653 |
| 678 | Asthma | Human | Sputum | TGFB1 | Microarray | Transcriptomics | High Throughput | TGFB1 level was up regulated in asthmatics belonging to the eosinophilic phenotype but was down regulated in neutrophilic and highly atopic asthmatics. | 30928653 |
| 679 | Asthma | Human | Sputum | LYZ | Mass Spectrometry | Proteomics | High Throughput | Sputum Lysozyme C expression level can aid in distinguishing between the subphenotypes within the highly atopic phenotype of asthma. | 30928653 |
| 680 | Asthma | Human | Sputum | TKT | Mass Spectrometry | Proteomics | High Throughput | Sputum Transketolase level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 681 | Asthma | Human | Sputum | CAT | Mass Spectrometry | Proteomics | High Throughput | Sputum Catalase level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 682 | Asthma | Human | Sputum | SERPINF1 | Mass Spectrometry | Proteomics | High Throughput | Sputum Pigment epithelium-derived factor expression level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 683 | Asthma | Human | Sputum | CFB | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Complement factor B level can aid in distinguishing between the subphenotypes within the eosinophilic and neutrophilic phenotype of asthma. | 30928653 |
| 684 | Asthma | Human | Sputum | MUC1 | Mass Spectrometry | Proteomics | High Throughput | Differences in sputum Mucin1 expression level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 685 | Asthma | Human | Sputum | TALDO | Mass Spectrometry | Proteomics | High Throughput | Differences in sputum Transaldolase expression level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 686 | Asthma | Human | Sputum | FGG | Mass Spectrometry | Proteomics | High Throughput | Sputum fibrinogen gamma chain expression level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 687 | Asthma | Human | Sputum | ZG16B | Mass Spectrometry | Proteomics | High Throughput | Sputum Zymogen granule protein 16 homolog B expression level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 688 | Asthma | Human | Sputum | IGHG1 | Mass Spectrometry | Proteomics | High Throughput | Sputum Immunoglobulin heavy constant gamma 1 level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 689 | Asthma | Human | Sputum | ALDOA | Mass Spectrometry | Proteomics | High Throughput | Sputum fructose-bisphosphate aldolase a level can aid in distinguishing between the subphenotypes within the neutrophilic phenotype of asthma. | 30928653 |
| 690 | Asthma | Human | Sputum | PRR4 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Proline-rich protein 4 level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 691 | Asthma | Human | Sputum | MYH13 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Myosin-13 level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 692 | Asthma | Human | Sputum | MYH7 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Myosin-7 level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 693 | Asthma | Human | Sputum | LDHA | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum L-lactate dehydrogenase A chain level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 694 | Asthma | Human | Sputum | TCN1 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Transcobalamin-1 level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 695 | Asthma | Human | Sputum | TPI | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Triosephosphate isomerase level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 696 | Asthma | Human | Sputum | IGHV3-20 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum Immunoglobulin heavy variable 3-20 level can aid in distinguishing between the subphenotypes within the eosinophilicphenotype of asthma. | 30928653 |
| 697 | Asthma | Human | Sputum | ALDH3B1 | Mass Spectrometry | Proteomics | High Throughput | Difference in sputum ALDH3B1 expression level can aid in distinguishing between the subphenotypes within the eosinophilic phenotype of asthma. | 30928653 |
| 698 | Severe Asthma | Human | Induced Sputum | MPO | ELISA | Others | Low Throughput | Sputum MPO levels were significantly higher in eDNA-high patients than in eDNA-low patients. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 699 | Severe Asthma | Human | Induced Sputum | NE | ELISA | Others | Low Throughput | NE-DNA complexes are increased in eDNA-high patients but not in eDNA-low patients. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 700 | Severe Asthma | Human | Induced Sputum | H3 | ELISA | Others | Low Throughput | H3Cit-DNA complexes are increased in eDNA-high patients but not in eDNA-low patients. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 701 | Severe Asthma | Human | Induced Sputum | CASP1 | Caspase-Glo1 Inflammasome assay | Others | Low Throughput | Increased caspase-1 activity in sputum was noted in eDNA-high asthma. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 702 | Severe Asthma | Human | Induced Sputum | IL1B | ELISA | Others | Low Throughput | Increased IL1B in sputum was noted in eDNA-high asthma. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 703 | Severe Asthma | Human | Induced Sputum | IL18 | ELISA | Others | Low Throughput | Low levels of IL18 in sputum was noted in eDNA-high asthma. eDNA-high asthma is characterized by multiple clinical indicators of asthma severity. | 30888839 |
| 704 | Asthma | Human | Induced Sputum | LRG | ELISA | Others | Low Throughput | Sputum LRG concentrations were significantly higher in patients with asthma than in healthy volunteers. | 27611322 |
| 705 | Asthma | Human | Blood Plasma, Induced Sputum | miR-199a-5p | qRT-PCR | Genomics | Low Throughput | The miRNA-199a-5p levels in plasma and sputum were increased significantly in patients with neutrophilic asthma compared to healthy subjects. Plasma miR-199a-5p was negatively correlated with pulmonary function. | 29505605 |
| 706 | Obese Asthma | Human | Induced Sputum | NOD1 | RNA Quantitation Assay Kit | Genomics | High Throughput | NOD1 gene expression was upregulated in obese asthmatics versus nonobese asthmatic patients. | 29857009 |
| 707 | Obese Asthma | Human | Induced Sputum | NLRP3 | RNA Quantitation Assay Kit | Genomics | High Throughput | NLRP3 gene expression was upregulated in obese asthmatics versus nonobese asthmatic patients. Saturated fatty acid meal led to increase in sputum neutrophil percentages and sputum cell gene expression of NLRP3 at 4 hours in nonobese asthmatic patients. The NLRP3 inflammasome is a potential therapeutic target in asthmatic patients. | 29857009 |
| 708 | Obese Asthma | Human | Induced Sputum | IL1B | ELISA | Others | Low Throughput | Sputum IL1B protein level was greater in obese asthmatics versus nonobese asthmatic patients. | 29857009 |
| 709 | Obese Asthma | Human | Induced Sputum | TLR4 | RNA Quantitation Assay Kit | Genomics | High Throughput | Saturated fatty acid meal led to increase in sputum neutrophil percentages and sputum cell gene expression of TLR4 at 4 hours in nonobese asthmatic patients. | 29857009 |
| 710 | Obese Asthma | Human | Induced Sputum | IL5 | RNA Quantitation Assay Kit | Genomics | High Throughput | IL5 was the most significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 711 | Obese Asthma | Human | Induced Sputum | TREM2 | RNA Quantitation Assay Kit | Genomics | High Throughput | TREM2 was significantly down regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 712 | Obese Asthma | Human | Induced Sputum | GNGT1 | RNA Quantitation Assay Kit | Genomics | High Throughput | GNGT1 was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 713 | Obese Asthma | Human | Induced Sputum | IRF7 | RNA Quantitation Assay Kit | Genomics | High Throughput | IRF7 was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 714 | Obese Asthma | Human | Induced Sputum | FASLG | RNA Quantitation Assay Kit | Genomics | High Throughput | FASLG was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 715 | Obese Asthma | Human | Induced Sputum | IL9 | RNA Quantitation Assay Kit | Genomics | High Throughput | IL9 was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 716 | Obese Asthma | Human | Induced Sputum | IL12B | RNA Quantitation Assay Kit | Genomics | High Throughput | IL12B was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 717 | Obese Asthma | Human | Induced Sputum | C1R | RNA Quantitation Assay Kit | Genomics | High Throughput | C1R was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 718 | Obese Asthma | Human | Induced Sputum | TBXA2R | RNA Quantitation Assay Kit | Genomics | High Throughput | TBXA2R was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 719 | Obese Asthma | Human | Induced Sputum | TGFB2 | RNA Quantitation Assay Kit | Genomics | High Throughput | TGFB2 was significantly up regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 720 | Obese Asthma | Human | Induced Sputum | TGFBR1 | RNA Quantitation Assay Kit | Genomics | High Throughput | TGFBR1 was significantly down regulated gene in obese asthmatics as compared to non obese asthmatics. | 29857009 |
| 721 | Childhood Asthma | Human | Induced Sputum | PTX3 | ELISA | Others | Low Throughput | Sputum PTX3 concentration was significantly higher in children with asthma than in control subjects. Sputum PTX3 levels correlated with atopic status and disease severity among patients with asthma. A positive significant correlation was found between sputum PTX3 and the bronchodilator response. | 28002338 |
| 722 | Obese Asthma | Human | Blood Plasma, Induced Sputum | IL17 | ELISA | Others | Low Throughput | Obesity promotes increased sputum and plasma IL17 expression in stable asthma patients. IL17 contributes to worse disease control in obese asthma through enhancing airway neutrophilia and depression and may implicate in asthma exacerbations. | 27888992 |
| 723 | Asthma | Human | Sputum | TNF-R2 | ELISA | Others | Low Throughput | Sputum TNF-R2 was significantly elevated in Aspergillus Fumigatus Culture-Positive Asthmatics. | 28102063 |
| 724 | Allergic Asthma | Human | Induced Sputum | miR-155 | qRT-PCR | Genomics | Low Throughput | Significantly lower levels of miR-155 were detected in cell-free sputum from allergic asthmatics compared to healthy controls. | 28199728 |
| 725 | Asthma | Human | Induced Sputum | CB1 | Western Blotting | Proteomics | Low Throughput | CB1 was not detected in healthy subjects, but was present in induced sputum from asthmatics. There was a significant and strong inverse correlation between CB1 level and the percentage of post bronchodilator forced expiratory volume in 1 second. | 30481497 |
| 726 | Asthma | Human | Induced Sputum | CB2 | Western Blotting | Proteomics | Low Throughput | CB2 was not detected in healthy subjects, but was present in induced sputum from asthmatics. | 30481497 |
| 727 | Severe Refractory Asthma (SRA) | Human | Sputum, Broncho Alveolar Lavage | INHBA | ELISA | Others | Low Throughput | Sputum and BAL activin A was significantly higher in patients with SRA compared to mild-to-moderate asthma. | 27807906 |
| 728 | Severe Refractory Asthma (SRA) | Human | Sputum, Broncho Alveolar Lavage | ECP | Unicap ECP Assay | Others | Low Throughput | ECP was significantly higher in patients with SRA compared to mild-to-moderate asthma and healthy control. | 27807906 |
| 729 | Severe Refractory Asthma (SRA) | Human | Sputum, Broncho Alveolar Lavage | IL13 | ELISA | Others | Low Throughput | IL13 was significantly higher in patients with SRA compared to mild-to-moderate asthma and healthy control. | 27807906 |
| 730 | Severe Refractory Asthma (SRA) | Human | Sputum, Broncho Alveolar Lavage | IL8 | ELISA | Others | Low Throughput | IL8 was significantly higher in patients with SRA compared to mild-to-moderate asthma and healthy control. | 27807906 |
| 731 | Severe Refractory Asthma (SRA) | Human | Sputum, Broncho Alveolar Lavage | TGFB1 | ELISA | Others | Low Throughput | TGFB1 was significantly higher in patients with SRA compared to mild-to-moderate asthma and healthy control. | 27807906 |
| 732 | Asthma | Human | Induced Sputum | IP10 | ELISA | Others | Low Throughput | Sputum concentrations of IP10 were significantly higher in asthma than in healthy subjects. | 27965774 |
| 733 | Asthma | Human | Induced Sputum | MIG | ELISA | Others | Low Throughput | Sputum concentrations of MIG were significantly higher in asthma than in healthy subjects. MIG was significantly negatively correlated with forced expiratory volume in 1 s % predicted (% FEV1) in patients with asthma. | 27965774 |
| 734 | Asthma | Human | Induced Sputum | IL8 | ELISA | Others | Low Throughput | Sputum concentrations of IL8 were significantly higher in asthma than in healthy subjects. IL8 was significantly negatively correlated with forced expiratory volume in 1 s % predicted (% FEV1) in patients with asthma. | 27965774 |
| 735 | Neutrophilic Asthma | Human | Sputum Cells | IFNB | qRT-PCR, ELISA | Genomics, Others | Low Throughput | Increased expression of IFNB in asthmatics was observed as compared with healthy subjects. The overexpression was restricted to neutrophilic asthmatics, while eosinophilic asthmatics did not differ from healthy subjects. | 27622317 |
| 736 | Neutrophilic Asthma | Human | Sputum Cells | IL29 | qRT-PCR, ELISA | Genomics, Others | Low Throughput | Increased expression of IL29 in asthmatics was observed as compared with healthy subjects. The overexpression was restricted to neutrophilic asthmatics, while eosinophilic asthmatics did not differ from healthy subjects. | 27622317 |
| 737 | Neutrophilic Asthma | Human | Sputum Cells | OASL | qRT-PCR | Genomics | Low Throughput | Increased expression of OAS in asthmatics was observed as compared with healthy subjects. The overexpression was restricted to neutrophilic asthmatics, while eosinophilic asthmatics did not differ from healthy subjects. | 27622317 |
| 738 | Neutrophilic Asthma | Human | Sputum Cells | RSAD2 | qRT-PCR | Genomics | Low Throughput | Increased expression of RSAD2 in asthmatics was observed as compared with healthy subjects. The overexpression was restricted to neutrophilic asthmatics, while eosinophilic asthmatics did not differ from healthy subjects. | 27622317 |
| 739 | Asthma | Human | Induced Sputum | TLR4 | Flow Cytometry | Others | Low Throughput | Asthmatic subjects with high total serum IgE show increased macrophage expression of TLR4 in induced sputum. | 27084682 |
| 740 | Asthma, COPD | Human | Induced Sputum | IL1B | ELISA | Others | Low Throughput | Significantly higher concentration of IL1B in induced sputum was detected in COPD patients than in asthmatic subjects. | 27265531 |
| 741 | Asthma, COPD | Human | Induced Sputum | MMP9 | ELISA | Others | Low Throughput | Significantly higher concentration of MMP9 in induced sputum was detected in COPD patients than in asthmatic subjects. | 27265531 |
| 742 | Asthma | Human | Induced Sputum | MUC5AC | ELISA | Others | Low Throughput | Asthma is characterized by an increase in MUC5AC in induced sputum. | 27845589 |
| 743 | Asthma | Human | Induced Sputum | MUC5B | ELISA | Others | Low Throughput | MUC5B is the predominant mucin in healthy airway mucus. Asthma is characterized by a decrease in MUC5B. Patients with asthma with a predominance of MUC5B in their mucin preparations have significantly lower numbers of eosinophils in their sputum. | 27845589 |
| 744 | Asthma, Eosinophilic Bronchitis (EB) | Human | Sputum | TARC | ELISA | Others | Low Throughput | Elevated TARC levels in sputum were detected in children with asthma but not in children with EB. Sputum TARC could be a supportive marker for discrimination of asthma from EB in children showing characteristics of eosinophilic airway inflammation. | 28238403 |
| 745 | Childhood Asthma | Human | Sputum | HMGB1 | ELISA | Others | Low Throughput | Sputum HMGB1 levels were significantly higher in all the patients with asthma. HMGB1 is a sensitive biomarker of allergic asthma in children. Asignificant correlation between the decrease of HMGB1 levels and a successful treatment response was also observed. | 28441990 |
| 746 | Asthma | Human | Induced Sputum | IL32 | ELISA | Others | Low Throughput | The IL32 level of sputum were negatively correlated with FEV1% predicted. The level of IL32γ in induced sputum may be associated with asthma severity and related with higher risk of asthma exacerbation. | 28732840 |
| 747 | Acute Asthma | Human | Sputum | MUC5AC | Western Blotting | Proteomics | Low Throughput | Sputum MUC5AC concentration in acute asthma patients was significantly elevated as compared to stable asthma and healthy control. | 28716644 |
| 748 | Acute Asthma | Human | Sputum | MUC5B | Western Blotting | Proteomics | Low Throughput | Sputum MUC5B concentration in acute asthma patients was significantly reduced as compared to stable asthma and healthy control. | 28716644 |
| 749 | Allergic Asthma (Inhaled Allergen Challenge) | Human | Eosinophils from Peripheral Blood and Induced Sputum | ST2L | Multiplex Immunoassay, Immunofluorescence Staining, Flow Cytometry | Others | Low Throughput | Levels of sST2 were measurable in all subjects and were significantly higher in both plasma and sputum supernatant of allergic asthmatics compared to healthy controls. In mild asthmatics, there was a significant upregulation of ST2L surface expression on eosinophils from blood and sputum following allergen inhalation challenge | 29694974 |
| 750 | Severe Asthma | Human | Sputum | YKL40 | ELISA | Others | Low Throughput | Severe Asthma was associated with increased sputum YKL40 expression. YKL40 levels strongly correlated with neutrophilic asthma. | 26851968 |
| 751 | Severe Asthma | Human | Sputum | MMP1 | Cytometric Bead Array | Others | High Throughput | Severe Asthma was associated with increased sputum MMP1 expression. | 26851968 |
| 752 | Severe Asthma | Human | Sputum | MMP3 | Cytometric Bead Array | Others | High Throughput | Severe Asthma was associated with increased sputum MMP3 expression. | 26851968 |
| 753 | Severe Asthma | Human | Sputum | MMP8 | Cytometric Bead Array | Others | High Throughput | Severe Asthma was associated with increased sputum MMP8 expression. | 26851968 |
| 754 | Severe Asthma | Human | Sputum | MMP12 | Cytometric Bead Array | Others | High Throughput | Severe Asthma was associated with increased sputum MMP12 expression. | 26851968 |
| 755 | Severe Asthma | Human | Sputum | IL5 | ELISA | Others | Low Throughput | Sputum IL5 levels were increased in patients with severe asthma particularly eosinophilic forms. | 26851968 |
| 756 | Severe Asthma | Human | Sputum | IL13 | Cytometric Bead Array | Others | High Throughput | Sputum IL13 levels were increased in patients with severe asthma particularly eosinophilic forms. | 26851968 |
| 757 | Severe Asthma | Human | Sputum | VEGF | ELISA | Others | Low Throughput | Sputum VEGF levels were increased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 758 | Severe Asthma | Human | Sputum | sIL6R | ELISA | Others | Low Throughput | Sputum sIL6R levels were increased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 759 | Severe Asthma | Human | Sputum | IL6 | ELISA | Others | Low Throughput | Sputum IL6 levels were increased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 760 | Severe Asthma | Human | Sputum | IL8 | Cytometric Bead Array | Others | High Throughput | Sputum IL8 levels were increased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 761 | Severe Asthma | Human | Sputum | IL2 | Cytometric Bead Array | Others | High Throughput | Sputum IL2 levels were decreased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 762 | Severe Asthma | Human | Sputum | IL1RA | Cytometric Bead Array | Others | High Throughput | Sputum IL1RA levels were decreased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 763 | Severe Asthma | Human | Sputum | FGF | ELISA | Others | Low Throughput | Sputum FGF levels were decreased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 764 | Severe Asthma | Human | Sputum | TIMP1 | Cytometric Bead Array | Others | High Throughput | Sputum TIMP1 levels were decreased in patients with severe asthma as compared to healthy controls. | 26851968 |
| 765 | Asthma with Depression | Human | Serum, Sputum | IL1B | ELISA, Human Cytokine/Chemokine Bead Panel | Others | Low Throughput, High Throughput | Level of IL1B in the serum and sputum were elevated in the depressive asthmatics compared to those in the non‐depressive group. | 30675924 |
| 766 | Asthma with Depression | Human | Serum, Sputum | IFNG | ELISA, Human Cytokine/Chemokine Bead Panel | Others | Low Throughput, High Throughput | Level of IFNG in the serum and sputum were elevated in the depressive asthmatics compared to those in the non‐depressive group. | 30675924 |
| 767 | Pediatric Severe Asthma | Human | Induced Sputum Cells | FPR2 | Immunocytochemistry | Others | Low Throughput | FPR2/ALXR expression was reduced in induced sputum cells of children with severe asthma (SA) compared with that seen in healthy controls and children with intermittent asthma(IA). | 26971688 |
| 768 | Asthma | Human | Sputum | IL1R1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IL1R1 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 769 | Asthma | Human | Sputum | PRSS33 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | PRSS33 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 770 | Asthma | Human | Sputum | CLC | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CLC characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 771 | Asthma | Human | Sputum | GPR42 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | GPR42 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 772 | Asthma | Human | Sputum | LGALS12 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | LGALS12 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 773 | Asthma | Human | Sputum | SOCS2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SOCS2 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 774 | Asthma | Human | Sputum | ALOX15 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | ALOX15 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 775 | Asthma | Human | Sputum | TARP | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TARP characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 776 | Asthma | Human | Sputum | ATP2A3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | ATP2A3 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 777 | Asthma | Human | Sputum | TRGV9 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TRGV9 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 778 | Asthma | Human | Sputum | FAM101B | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | FAM101B characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 779 | Asthma | Human | Sputum | CD24 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CD24 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 780 | Asthma | Human | Sputum | CRCLF2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CRCLF2 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 781 | Asthma | Human | Sputum | TRGC2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TRGC2 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 782 | Asthma | Human | Sputum | TPSB2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TPSB2 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 783 | Asthma | Human | Sputum | OLIG2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | OLIG2 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 784 | Asthma | Human | Sputum | HRH4 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | HRH4 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 785 | Asthma | Human | Sputum | CPA3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CPA3 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 786 | Asthma | Human | Sputum | CCR3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CCR3 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 787 | Asthma | Human | Sputum | VSTM1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | VSTM1 characterized TAC1. Transcriptome-associated cluster1(TAC1) he highest sputum eosinophilia and exhaled nitric oxide fraction, and was restricted to severe asthma with oral corticosteroid dependency, frequent exacerbations and severe airflow obstruction. | 28179442 |
| 788 | Asthma | Human | Sputum | CLEC4D | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CLEC4D characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 789 | Asthma | Human | Sputum | CXCR1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CXCR1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 790 | Asthma | Human | Sputum | IFITM1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IFITM1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 791 | Asthma | Human | Sputum | MGAM | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | MGAM characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 792 | Asthma | Human | Sputum | FPR2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | FPR2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 793 | Asthma | Human | Sputum | KRT23 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | KRT23 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 794 | Asthma | Human | Sputum | FAM65B | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | FAM65B characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 795 | Asthma | Human | Sputum | IL18RAP | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IL18RAP characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 796 | Asthma | Human | Sputum | VNN3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | VNN3 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 797 | Asthma | Human | Sputum | VNN2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | VNN2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 798 | Asthma | Human | Sputum | SMCHD1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SMCHD1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 799 | Asthma | Human | Sputum | CLEC4E | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CLEC4E characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 800 | Asthma | Human | Sputum | DYSF | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | DYSF characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 801 | Asthma | Human | Sputum | CREB5 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CREB5 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 802 | Asthma | Human | Sputum | MSRB1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | MSRB1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 803 | Asthma | Human | Sputum | CXCR2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CXCR2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 804 | Asthma | Human | Sputum | LINC01093 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | LINC01093 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 805 | Asthma | Human | Sputum | CASP4 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CASP4 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 806 | Asthma | Human | Sputum | TSPAN2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TSPAN2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 807 | Asthma | Human | Sputum | KCNJ15 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | KCNJ15 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 808 | Asthma | Human | Sputum | IDI2-AS1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IDI2-AS1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 809 | Asthma | Human | Sputum | SULT1B1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SULT1B1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 810 | Asthma | Human | Sputum | TREML2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TREML2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 811 | Asthma | Human | Sputum | IFIT2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IFIT2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 812 | Asthma | Human | Sputum | TNFAIP3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TNFAIP3 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 813 | Asthma | Human | Sputum | SPATA13 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SPATA13 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 814 | Asthma | Human | Sputum | TLR1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TLR1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 815 | Asthma | Human | Sputum | TNFSF10 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TNFSF10 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 816 | Asthma | Human | Sputum | NMI | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | NMI characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 817 | Asthma | Human | Sputum | LIMK2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | LIMK2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 818 | Asthma | Human | Sputum | UBE2D1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | UBE2D1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 819 | Asthma | Human | Sputum | SAMSN1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SAMSN1 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 820 | Asthma | Human | Sputum | WDFY3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | WDFY3 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 821 | Asthma | Human | Sputum | REPS2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | REPS2 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 822 | Asthma | Human | Sputum | NAIP | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | NAIP characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 823 | Asthma | Human | Sputum | DDIT4 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | DDIT4 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 824 | Asthma | Human | Sputum | IFITM3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | IFITM3 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 825 | Asthma | Human | Sputum | MEFV | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | MEFV characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 826 | Asthma | Human | Sputum | SLC7A5 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SLC7A5 characterized Transcriptome-associated cluster2 (TAC2). TAC2 showed the highest sputum neutrophilia, serum C-reactive protein levels and prevalence of eczema. | 28179442 |
| 827 | Asthma | Human | Sputum | SCARB2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SCARB2 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 828 | Asthma | Human | Sputum | SUCLG2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SUCLG2 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 829 | Asthma | Human | Sputum | ATP1B1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | ATP1B1 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 830 | Asthma | Human | Sputum | ZYG11B | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | ZYG11B characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 831 | Asthma | Human | Sputum | LINC01094 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | LINC01094 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 832 | Asthma | Human | Sputum | TGOLN2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TGOLN2 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 833 | Asthma | Human | Sputum | HLA-DMB | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | HLA-DMB characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 834 | Asthma | Human | Sputum | PLBD1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | PLBD1 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 835 | Asthma | Human | Sputum | SCOC | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | SCOC characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 836 | Asthma | Human | Sputum | OAS1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | OAS1 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 837 | Asthma | Human | Sputum | CSTA | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | CSTA characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 838 | Asthma | Human | Sputum | TBC1D4 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | TBC1D4 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 839 | Asthma | Human | Sputum | LSM6 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | LSM6 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 840 | Asthma | Human | Sputum | PQLC3 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | PQLC3 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 841 | Asthma | Human | Sputum | MRPL57 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | MRPL57 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 842 | Asthma | Human | Sputum | ZCRB1 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | ZCRB1 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 843 | Asthma | Human | Sputum | PDCD2 | Microarray Data Analysis | Genomics, Bioinformatics | High Throughput | PDCD2 characterized Transcriptome-associated cluster 3 (TAC3). TAC3 had normal to moderately high sputum eosinophils and better preserved forced expiratory volume in 1 s. | 28179442 |
| 844 | Asthma | Human | Sputum | IL8 | ELISA | Others | Low Throughput | IL8 was higher in patients with neutrophilic and mixed asthma as compared to that with eosinophilic and paucigranulocytic asthma. | 28407269 |
| 845 | Asthma | Human | Sputum | ECP | Unicap ECP Assay | Others | Low Throughput | ECP was higher in eosinophilic and mixed asthma as compared to neutrophilic asthma and paucigranulocytic asthma. | 28407269 |
| 846 | Asthma | Human | Sputum, Airway Macrophages | AXL | qRT-PCR | Genomics | Low Throughput | The levels of soluble AXL in sputum samples were significantly elevated in patients with asthma compared with controls. AXL expression was significantly reduced in airway macrophages from patients with asthma. | 28412392 |
| 847 | Asthma | Human | Nasal Secretion, Sputum | IL13 | ELISA | Others | Low Throughput | Nasal secretion and sputum level of IL13 was increased in asthmatic patients in season as compared with out of season. | 30121290 |
| 848 | Asthma | Human | Sputum | IL24 | ELISA | Others | Low Throughput | Sputum level of IL24 was increased in asthmatic patients in season as compared with out of season. | 30121290 |
| 849 | Severe Asthma | Human | Sputum | CSF2 | SOMAscan Proteomic Assay | Proteomics | High Throughput | Colony stimulating factor (CSF)2 protein levels were increased in Current Smokers Severe asthmatics' sputum supernatants. | 29650557 |
| 850 | Severe Asthma | Human | Sputum | ELANE | SOMAscan Proteomic Assay | Proteomics | High Throughput | ELANE was upregulated in ex smoker severe asthmatics. | 29650557 |
| 851 | Severe Asthma | Human | Sputum | CXCL8 | SOMAscan Proteomic Assay | Proteomics | High Throughput | CXCL8 was upregulated in ex smoker severe asthmatics. | 29650557 |
| 852 | Severe Asthma | Human | Sputum | AZU1 | SOMAscan Proteomic Assay | Proteomics | High Throughput | AZU1 was upregulated in ex smoker severe asthmatics. | 29650557 |
| 853 | Severe Asthma | Human | Sputum | AGR2 | SOMAscan Proteomic Assay | Proteomics | High Throughput | AGR2 expression was increased in Current Smokers Severe asthmatics' sputum supernatants. | 29650557 |
| 854 | Severe Asthma | Human | Sputum | PDIA3 | SOMAscan Proteomic Assay | Proteomics | High Throughput | PDIA3 was differentially expressed amongst ex smoker and non smoker groups of severe asthmatics. | 29650557 |
| 855 | Severe Asthma | Human | Sputum | CAT | SOMAscan Proteomic Assay | Proteomics | High Throughput | The protein expression of CAT was upregulated equally in all severe asthma groups compared with healthy subjects. | 29650557 |
| 856 | Severe Asthma | Human | Sputum | MUC5AC | Microarray | Transcriptomics | High Throughput | MUC5AC expression was increased in Current Smokers Severe asthmatics' sputum supernatants. | 29650557 |
| 857 | Severe Asthma | Human | Sputum | GZMB | SOMAscan Proteomic Assay | Proteomics | High Throughput | GZMB was differentially expressed amongst ex smoker and non smoker groups of severe asthmatics. | 29650557 |
| 858 | Severe Asthma | Human | Sputum | CD5L | SOMAscan Proteomic Assay | Proteomics | High Throughput | CD5L was differentially expressed amongst ex smoker and non smoker groups of severe asthmatics. | 29650557 |
| 859 | Severe Asthma | Human | Sputum | MMP12 | Microarray | Transcriptomics | High Throughput | MMP12 was up regulated in sputum of ex smokers severe asthmatics. | 29650557 |
| 860 | Severe Asthma | Human | Sputum | NRP1 | Microarray | Transcriptomics | High Throughput | NRP1 was up regulated in sputum of ex smokers severe asthmatics. | 29650557 |
| 861 | Severe Asthma | Human | Sputum | TIRAP | Microarray | Transcriptomics | High Throughput | TIRAP was up regulated in sputum of ex smokers severe asthmatics. | 29650557 |
| 862 | Severe Asthma | Human | Sputum | CXCL5 | Microarray | Transcriptomics | High Throughput | CXCL5 was up regulated in sputum of ex smokers severe asthmatics. | 29650557 |
| 863 | Severe Asthma | Human | Sputum | PPBP | Microarray | Transcriptomics | High Throughput | PPBP was up regulated in sputum of ex smokers severe asthmatics. | 29650557 |
| 864 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | CPA3 | Microarray | Transcriptomics | High Throughput | CPA3 was differentially expressed in ex smoker severe asthmatics compared to non smoker severe asthmatics. | 29650557 |
| 865 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | CST1 | Microarray | Transcriptomics | High Throughput | CST1 was differentially expressed in ex smoker severe asthmatics compared to non smoker severe asthmatics. | 29650557 |
| 866 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | IGKC | Microarray | Transcriptomics | High Throughput | IGKC was differentially expressed in ex smoker severe asthmatics compared to non smoker severe asthmatics. | 29650557 |
| 867 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | MUC2 | Microarray | Transcriptomics | High Throughput | MUC2 was differentially expressed in ex smoker severe asthmatics compared to non smoker severe asthmatics. | 29650557 |
| 868 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | TPSAB1 | Microarray | Transcriptomics | High Throughput | TPSAB1 was differentially expressed in ex smoker severe asthmatics compared to non smoker severe asthmatics. | 29650557 |
| 869 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | FDCSP | Microarray | Transcriptomics | High Throughput | FDCSP was significantly up regulated in ex smoker severe asthmatics. | 29650557 |
| 870 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | PPBP | Transcriptomics | High Throughput | PPBP was significantly up regulated in ex smoker severe asthmatics. | 29650557 | |
| 871 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | POSTN | Transcriptomics | High Throughput | POSTN was significantly down regulated in ex smoker severe asthmatics. | 29650557 | |
| 872 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | IGLC1 | Transcriptomics | High Throughput | IGLC1 was significantly down regulated in ex smoker severe asthmatics. | 29650557 | |
| 873 | Severe Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum | IGLV | Transcriptomics | High Throughput | IGLV was significantly down regulated in ex smoker severe asthmatics. | 29650557 | |
| 874 | Atopic Asthma (Following Allergen Challenge) | Human | Sputum, Broncho Alveolar Lavage Fluid (BALF) | IL5 | Meso Scale Discovery System (ELISA) | Others | High Throughput | IL5 level was increased post allergen challenge. | 29651336 |
| 875 | Atopic Asthma (Following Allergen Challenge) | Human | Sputum, Broncho Alveolar Lavage Fluid (BALF) | ECP | Meso Scale Discovery System (ELISA) | Others | High Throughput | ECP level was increased post allergen challenge. | 29651336 |
| 876 | Asthma | Human | Sputum, Serum, Peripheral Blood Mononuclear Cells (PBMCs) | CD163 | ELISA, Flow Cytometry | Others | Low Throughput | Sputum sCD163 level significantly increased in asthma, unlike healthy controls. Sputum sCD163 and serum sCD163 levels were significantly higher in patients with severe asthma compared to those with mild/moderate asthma. Increased sCD163 levels in sputum are associated with the impairment of lung function. Percentage of CD163+ monocytes in patients with asthma was significantly lower than the controls. | 30246699 |
| 877 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | tPA | Olink proximity extension analysis | Proteomics | High Throughput | Sputum tPA level efficiently distinguished controlled and poorly controlled asthmatics. Sputum tPA level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 878 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | KLK6 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum KLK6 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum KLK6 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 879 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | RETN | Olink proximity extension analysis | Proteomics | High Throughput | Sputum RETN level efficiently distinguished controlled and poorly controlled asthmatics. Sputum RETN level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 880 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | ADA | Olink proximity extension analysis | Proteomics | High Throughput | Sputum ADA level efficiently distinguished controlled and poorly controlled asthmatics. Sputum ADA level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 881 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | MMP9 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum MMP9 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum MMP9 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 882 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | CHIT1 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum CHIT1 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum CHIT1 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 883 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | GRN | Olink proximity extension analysis | Proteomics | High Throughput | Sputum GRN level efficiently distinguished controlled and poorly controlled asthmatics. Sputum GRN level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 884 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | PGLYRP1 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum PGLYRP1 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum PGLYRP1 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 885 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | MPO | Olink proximity extension analysis | Proteomics | High Throughput | Sputum MPO level efficiently distinguished controlled and poorly controlled asthmatics. Sputum MPO level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 886 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | HGF | Olink proximity extension analysis | Proteomics | High Throughput | Sputum HGF level efficiently distinguished controlled and poorly controlled asthmatics. Sputum HGF level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 887 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | PRTN3 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum PRTN3 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum PRTN3 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 888 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | DNER | Olink proximity extension analysis | Proteomics | High Throughput | Sputum DNER level efficiently distinguished controlled and poorly controlled asthmatics. Sputum DNER level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 889 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | PI3 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum PI3 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum PI3 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 890 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | OPG | Olink proximity extension analysis | Proteomics | High Throughput | Sputum OPG level efficiently distinguished controlled and poorly controlled asthmatics. Sputum OPG level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 891 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | ChI3L1 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum ChI3L1 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum CHI3L1 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 892 | Asthma (Controlled versus poorly controlled asthma) | Human | Induced Sputum | AZU1 | Olink proximity extension analysis | Proteomics | High Throughput | Sputum AZU1 level efficiently distinguished controlled and poorly controlled asthmatics. Sputum AZU1 level was significantly elevated in poorly controlled asthmatics as compared to well controlled asthmatics. | 29665127 |
| 893 | Eosinophilic Asthma | Human | Induced Sputum | PTX3 | ELISA | Others | Low Throughput | Subjects with non eosinophilic asthma had significantly increased PTX3 levels compared with those with eosinophilic asthma and healthy controls. Asthma patients with high sputum PTX3 levels had significantly lower sputum eosinophil percentages. Sputum PTX3 levels had the best power to predict non-eosinophilic airway inflammation in asthma patients. | 29754456 |
| 894 | Eosinophilic Asthma | Human | Induced Sputum | SAP | ELISA | Others | Low Throughput | Sputum SAP concentrations of eosinophilic asthmatics were significantly higher than those of non-eosinophilic patients and healthy controls. | 29754456 |
| 895 | Severe, Steroid-Resistant Asthma | Human | Sputum | IL1B | qRT-PCR | Genomics | Low Throughput | IL1B expression was significantly elevated in severe asthmatics as compared to mild asthmatics. Neutrophilic airway inflammation, disease severity, and steroid resistance in human asthma correlate with IL1B expression. | 28252317 |
| 896 | Severe, Steroid-Resistant Asthma | Human | Sputum | NLRP3 | qRT-PCR | Genomics | Low Throughput | NLRP3 expression was significantly elevated in severe asthmatics as compared to mild asthmatics. Neutrophilic airway inflammation, disease severity, and steroid resistance in human asthma correlate with NLRP3 expression. | 28252317 |
| 897 | Asthma | Human | Bronchial Biopsy, Bronchial Brushings, Sputum, Blood Plasma | ITLN1 | Immunohistochemistry, qRT-PCR, ELISA | Others, Genomics, Others | Low Throughput | The expression of ITLN1 is increased in the airway and plasma of subjects with asthma and is correlated with induced sputum eosinophils. | 28224996 |
| 898 | Asthma | Human | Induced Sputum | YAP1 | qRT-PCR | Genomics | Low Throughput | YAP1 expression was significantly reduced in induced sputum of asthmatic patients as compared to healthy controls. A correlation was found between YAP1 mRNA levels and sputum bronchial epithelial cells. | 28293931 |
| 899 | Asthma | Human | Induced Sputum | IL4 | qRT-PCR | Genomics | Low Throughput | IL4 expression was significantly increased in asthmatic patients as compared to healthy subjects. | 28231834 |
| 900 | Asthma | Human | Induced Sputum | IL13 | qRT-PCR | Genomics | Low Throughput | IL13 expression was significantly increased in asthmatic patients as compared to healthy subjects. | 28231834 |
| 901 | Asthma | Human | Induced Sputum | IL10 | qRT-PCR | Genomics | Low Throughput | IL10 expression was significantly increased in asthmatic patients as compared to healthy subjects. | 28231834 |
| 902 | Asthma | Human | Induced Sputum | IL5 | qRT-PCR | Genomics | Low Throughput | Patients with high IL5 were restricted to cluster 1 with increased sputum eosinophil as well as neutrophil counts and poor lung function parameters at baseline and 2 years later. | 28231834 |
| 903 | Asthma | Human | Induced Sputum | IL17A | qRT-PCR | Genomics | Low Throughput | Patients with high IL17A were restricted to cluster 1 with increased sputum eosinophil as well as neutrophil counts and poor lung function parameters at baseline and 2 years later. | 28231834 |
| 904 | Asthma | Human | Induced Sputum | IL17F | qRT-PCR | Genomics | Low Throughput | Patients with high IL17F were restricted to cluster 1 with increased sputum eosinophil as well as neutrophil counts and poor lung function parameters at baseline and 2 years later. | 28231834 |
| 905 | Asthma | Human | Induced Sputum | IL25 | qRT-PCR | Genomics | Low Throughput | Patients with high IL25 were restricted to cluster 1 with increased sputum eosinophil as well as neutrophil counts and poor lung function parameters at baseline and 2 years later. | 28231834 |
| 906 | Asthma | Human | Induced Sputum | IL6 | qRT-PCR | Genomics | Low Throughput | Asthmatic patients in cluster 3 had high IL6 sputum mRNA levels. | 28231834 |
| 907 | Asthma | Human | Induced Sputum | IL22 | qRT-PCR | Genomics | Low Throughput | Asthmatic patients in cluster 4 had high IL22 sputum mRNA levels. | 28231834 |
| 908 | Asthma | Human | Induced Sputum | IL1B | qRT-PCR | Genomics | Low Throughput | Asthmatic patients in cluster 4 had high IL1B sputum mRNA levels. | 28231834 |
| 909 | Asthma | Human | Airway Smooth Muscle Cells (ASMCs), Bronchial Tissues, Sputum | HMGB1 | qRT-PCR, Immunofluorescence, Flow cytometry, Immunohistochemistry, ELISA, Nonreducing electrophoresis, Western Blotting | Genomics, Others, Proteomics | Low Throughput | Sputum HMGB1 concentration was increased in those with severe asthma but not in those with mild to moderate asthma versus healthy controls. HMGB1 protein expression was significantly reduced in ASMCs from those with asthma versus controls. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4. | 28259445 |
| 910 | Asthma | Human | Induced Sputum | CHOP | Western Blotting | Proteomics | Low Throughput | CHOP expression was significantly increased in asthmatic patients as compared to healthy subjects. | 28238747 |
| 911 | Asthma | Human | Induced Sputum | BIP | Western Blotting | Proteomics | Low Throughput | BIP expression was significantly increased in asthmatic patients as compared to healthy subjects. | 28238747 |
| 912 | Asthma | Human | Airway Epithelial Cell Brushings, Sputum | IL6 | Microarray, ELISA | Transcriptomics, Others | High Throughput, Low Throughput | IL6 expression was increased in IL-6TS High asthma patients characterized by frequent exacerbations, eosinophilic airway inflammation and increased numbers of T cells and macrophages infiltrating the airway submucosa. | 29902480 |
| 913 | Asthma | Human | Sputum | sIL6R | ELISA | Others | Low Throughput | sIL6R expression was increased in IL-6TS High asthma patients characterized by frequent exacerbations, eosinophilic airway inflammation and increased numbers of T cells and macrophages infiltrating the airway submucosa. | 29902480 |
| 914 | Asthma (HDM Sensitized Symptomatic Asthma), Atopic Asthma | Human | Sputum Derived Cells, Bronchial Epithelial Cells (BECs) | EGFR | RNA Sequencing, Immunostaining | Transcriptomics, Others | High Throughput, Low Throughput | EGFR was up regulated in HDM sensitized wheezers as compared to HDM sensitized non-wheezers. EGFR expression was significantly higher in atopic asthmatic bronchial epithelial cells versus nonatopic controls. | 29367592 |
| 915 | Asthma (HDM Sensitized Symptomatic Asthma), Atopic Asthma | Human | Sputum Derived Cells, Bronchial Epithelial Cells (BECs) | ERBB2 | RNA Sequencing, Immunostaining | Transcriptomics, Others | High Throughput, Low Throughput | ERBB2 was up regulated in HDM sensitized wheezers as compared to HDM sensitized non-wheezers. ERBB2 expression was found to be higher in atopic asthmatic bronchial epithelial cells versus nonatopic controls. | 29367592 |
| 916 | Asthma (HDM Sensitized Symptomatic Asthma) | Human | Sputum Derived Cells | CDH1 | RNA Sequencing | Transcriptomics | High Throughput | CDH1 was up regulated in HDM sensitized wheezers as compared to HDM sensitized non-wheezers. | 29367592 |
| 917 | Asthma (HDM Sensitized Symptomatic Asthma), Atopic Asthma | Human | Sputum Derived Cells, Bronchial Epithelial Cells (BECs) | CDHR3 | RNA Sequencing, Immunostaining | Transcriptomics, Others | High Throughput, Low Throughput | CDHR3 was up regulated in HDM sensitized wheezers as compared to HDM sensitized non-wheezers. CDHR3 expression was significantly higher in atopic asthmatic bronchial epithelial cells versus nonatopic controls. | 29367592 |
| 918 | Asthma (HDM Sensitized Symptomatic Asthma) | Human | Sputum Derived Cells | IL13 | RNA Sequencing | Transcriptomics | High Throughput | IL13 was up regulated in HDM sensitized wheezers as compared to HDM sensitized non-wheezers. | 29367592 |
| 919 | Asthma, COPD | Human | Induced Sputum Cells | IL17 | qRT-PCR | Genomics | Low Throughput | The expression of IL17 was lower in patients with atopic asthma compared to non-atopic asthma patients. | 27739024 |
| 920 | Asthma, COPD | Human | Induced Sputum Cells | CXCL8 | qRT-PCR | Genomics | Low Throughput | CXCL8 expression was significantly less in asthmatic patients as compared to COPD patients. CXCL8 was strongly related to the neutrophil percentage but differed significantly in COPD and asthma patients. The percentage of macrophages correlated negatively with the expression of CXCL8 in asthma. | 27739024 |
| 921 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Induced Sputum | IL13 | ELISA | Others | Low Throughput | The sputum levels of IL13 was significantly increased in the ACOS groups when compared with the levels in the normal healthy subjects. Sputum IL13 level could not distinguish ACOS from COPD and asthma. | 27757028 |
| 922 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Induced Sputum | MPO | ELISA | Others | Low Throughput | Sputum MPO level was significantly elevated in ACOS when compared with healthy controls and asthma patients. Sputum MPO levels could distinguish between the ACOS and asthma groups. The sputum MPO could not distinguish ACOS from COPD. | 27757028 |
| 923 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Induced Sputum | NGAL | ELISA | Others | Low Throughput | Sputum NGAL level was significantly elevated in ACOS patients when compared with healthy controls, COPD and asthma patients. Sputum NGAL levels could differentiate ACOS from asthma and COPD. Sputum NGAL level was also significantly increased in the COPD group when compared with the asthma group. Sputum NGAL levels were independently correlated with the percentage of prebronchodilator forced expiratory volume in 1 second predicted in multivariate analysis. | 27757028 |
| 924 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Induced Sputum | YKL40 | ELISA | Others | Low Throughput | Sputum YKL40 level was significantly elevated in ACOS patients when compared with healthy controls, COPD and asthma patients. Sputum YKL40 level could differentiate ACOS from COPD and asthma. Sputum YKL40 levels were not significantly different between the COPD and asthma groups. | 27757028 |
| 925 | Asthma, COPD, Asthma COPD Overlap Syndrome (ACOS) | Human | Induced Sputum | IL6 | ELISA | Others | Low Throughput | Sputum IL6 level was significantly elevated in ACOS patients when compared with healthy controls, COPD and asthma patients. Sputum IL6 level could differentiate ACOS from COPD and asthma. Sputum IL6 level was also significantly increased in the COPD group when compared with the asthma group. | 27757028 |
| 926 | Allergic Asthma | Human | Sputum, Nasal Lavage Fluid | FABP5 | 2D-DIGE, Western Blotting, ELISA | Proteomics, Others | High Throughput, Low Throughput | FABP5 was up regulated in the sputum and nasal lavage fluid of asthmatics as compared to healthy controls. | 26020772 |
| 927 | Allergic Asthma | Human | Sputum, Nasal Lavage Fluid | VEGFA | 2D-DIGE, Western Blotting, ELISA | Proteomics, Others | High Throughput, Low Throughput | VEGFA level was increased in the nasal lavage fluid of asthmatics as compared to healthy controls. | 26020772 |
| 928 | Chronic Asthma | Human | Induced Sputum | CCL5 | ELISA | Others | Low Throughput | Increased levels of RANTES was noted in induced sputum of patients with chronic asthma but not in seasonal allergic rhinitis patients as compared to that in healthy subjects. | 17269368 |
| 929 | Asthma | Human | Sputum | SOD3 | RNA sequencing | Transcriptomics | High Throughput | Sputum SOD3 transcript increases with asthma severity. | 28878123 |