Browse Result

Total number of records for in D of in DAAB (Version-2) database: 76

Record no	GENE NAME	SNP ID	CHANGES	ANCESTRAL ALLELES	FUNCTIONAL CONSEQUENCES	DISEASE	POPULATION	Pubmed ID	Comments
1	DDX58	rs10813831	A/G	G	Missense Variant	Viral Respiratory Illness, Asthma	European or American European	26399222	A missense mutation rs10813831 (G/A; Arg7Cys change) was associated with loss of asthma control, both undefined and of viral origin and asthma symptom burden in RhinoGen study and with asthma at age 6 in COAST (Childhood Origins of Asthma) study.
2	DDX58	rs3205166	A/C/T	A	Synonymous Variant	Viral Respiratory Illness, Asthma	European or American European	26399222	rs3205166 (G/T) was associated with increased loss of asthma control, both undefined and of viral origin, and with the number of weeks infected in RhinoGen study and with the occurrence of asthma at age 6 and wheezing in the first 3 years of life in the COAST (Childhood Origins of Asthma) validation study.
3	DENND1B	rs73077640	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G of rs73077640 was positively associated with non atopic asthma when compared with control. The allele G of rs73077640 was positively associated with asthma severity. The allele G of rs73077640 was negatively associated with skin test for at least one allergen tested, Dermatophagoides pteronyssinus, Blomia tropicalis and Periplaneta americana.
4	DENND1B	rs6694441	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele C of rs6694441 was positively associated with non atopic asthma when compared with control. The allele C of rs6694441 was positively associated with asthma severity. The allele C of rs6694441 was negatively associated with skin test for at least one allergen tested, Dermatophagoides pteronyssinus, Blomia tropicalis and Periplaneta americana.
5	DENND1B	rs17641842	G/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G of rs17641842 was positively associated with specific IgE serum levels for Periplanata americana. The allele G of rs17641842 was positively associated with skin test for at least one allergen tested, Blomia tropicalis and Periplanata americana.
6	DENND1B	rs57589685	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele A of rs57589685 was positively associated with non atopic asthma when compared with control. The allele A of rs57589685 was positively associated with asthma severity. The allele A of rs57589685 was negatively associated with specific IgE serum levels and skin prick test for Blomia tropicalis.
7	DENND1B	rs10801621	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The rs10801621 was positively associated with specific IgE serum levels for Blatela gemanica and Periplanata americana. The allele G of rs10801621 was positively associated with skin test for at least one allergen tested, Blomia tropicalis, Blatela gemanica and Periplanata americana.
8	DENND1B	rs6685897	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele C of rs6685897 was positively associated with atopic asthma when compared with control. The allele C of rs6685897 was positively associated with specific IgE levels and skin prick test for Dermatophagoides pteronyssinus, Blomia tropicalis, Blatela gemanica and Periplanata americana.
9	DENND1B	rs73073636	A/G	G	Non Coding Transcript Variant	Asthma, Atopy	Brazilian children	28668455	The allele A of rs73073636 was positively associated with asthma severity. The allele A of rs73073636 was negatively associated with specific IgE serum levels for Blomia tropicalis.
10	DENND1B	rs981520	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele A of rs981520 was positively associated with skin test for fungi.
11	DENND1B	rs2147771	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele A of rs2147771 was positively associated with skin test for fungi.
12	DENND1B	rs4427436	A/C/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G of rs4427436 was positively associated with skin test for fungi.
13	DENND1B	rs3902061	G/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G rs3902061 was negatively associated with specific IgE serum levels for Periplanata americana. The allele G of rs3902061 was positively associated with skin test for fungi.
14	DENND1B	rs1421396	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The A allele of rs1421396 was positively associated with asthma. The allele A of rs1421396 was positively associated with skin test for fungi.
15	DENND1B	rs1421389	G/T	T	Non Coding Transcript Variant	Asthma, Atopy	Brazilian children	28668455	The allele C of rs1421389 was positively associated with asthma. The allele C of rs1421389 was positively associated with skin test for fungi.
16	DENND1B	rs12354257	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele C of rs12354257 presented positive association with with skin test for at least one allergen tested, Dermatophagoides pteronyssinus, Blomia tropicalis and Periplaneta americana. The rs12354257 (C) allele increases the expression of DENND1B in the whole blood.
17	DENND1B	rs2884629	A/C	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G of rs2884629 was positively associated with skin test for at least one allergen tested, Blomia tropicalis and Periplanata americana.
18	DENND1B	rs1998598	A/G/T	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The rs1998598 presented positive association with with skin test for at least one allergen tested, Dermatophagoides pteronyssinus, Blomia tropicalis and Periplaneta americana. The rs1998598 (G) allele increases the expression of DENND1B in the whole blood.
19	DENND1B	rs6691216	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The C allele of rs6691216 was negatively associated with asthma. The allele C of rs6691216 was negatively associated with asthma severity. The polymorphic allele of rs6691216 (C) decreases the expression of DENND1B in the whole blood.
20	DENND1B	rs11799915	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele G of rs11799915 was positively associated with skin test for at least one allergen tested, Blomia tropicalis and Periplanata americana.
21	DENND1B	rs1573100	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele C of rs1573100 was positively associated with skin test for at least one allergen tested and Blomia tropicalis. The rs1573100 (C) increases the expression of DENND1B in the whole blood.
22	DENND1B	rs4915551	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele A of rs4915551 was negatively associated with asthma severity. The allele A of rs4915551 was positively associated with specific IgE serum levels for Dermatophagoides pteronyssinus. The allele A of rs4915551 was positively associated with skin test for at least one allergen tested, Blomia tropicalis and Periplanata americana.
23	DENND1B	rs12066841	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele T of rs12066841 was positively associated with skin test for cat epithelium and negatively associated with skin test for Blatela gemanica.
24	DENND1B	rs16841893	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	The allele T of rs16841893 was positively associated with non atopic asthma when compared with control. The allele T of rs16841893 was positively associated with asthma severity.
25	DENND1B	rs17641524	C/G/T	C	Synonymous Variant	Asthma, Atopy	Brazilian children	28668455	The allele T of rs17641524 was positively associated with skin test for Dermatophagoides pteronyssinus and Blomia tropicalis. The rs17641524 (T) increases the expression of DENND1B in the whole blood.
26	DENND1B	rs4282851	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs4282851was positively associated with skin prick test for Blatela germanica.
27	DENND1B	rs12142127	C/T	C	Synonymous Variant	Asthma, Atopy	Brazilian children	28668455	rs12142127 was positively associated with skin prick test for Periplaneta americana.
28	DENND1B	rs12127378	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs12127378 was negatively associated with skin prick test for Blatela germanica.
29	DENND1B	rs80125218	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs80125218 was positively associated with specific IgE for Periplaneta americana.
30	DENND1B	rs77209687	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs77209687 was positively associated with skin prick test for fungi.
31	DENND1B	rs6680870	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs6680870 was positively associated with specific IgE for Periplaneta americana.
32	DENND1B	rs12125739	G/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs12125739 was negatively associated with skin prick test for Blomia tropicalis.
33	DENND1B	rs12117045	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs12117045 was positively associated with skin prick test for Blomia tropicalis.
34	DENND1B	rs74134858	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs74134858 was positively associated with skin prick test for Blatela germanica.
35	DENND1B	rs2287537	A/C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs2287537 was positively associated with skin prick test for Blatela germanica.
36	DENND1B	rs10494756	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10494756 was positively associated with skin prick test for Blatela germanica.
37	DENND1B	rs9633354	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs9633354 was positively associated with skin prick test for Blatela germanica.
38	DENND1B	rs4915550	A/C	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs4915550 was negatively associated with skin prick test for Blatela germanica.
39	DENND1B	rs201498005	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs201498005 was negatively associated with skin prick test for Blatela germanica.
40	DENND1B	rs4915552	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs4915552 was negatively associated with skin prick test for Blatela germanica.
41	DENND1B	rs10922257	A/G/T	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10922257 was negatively associated with skin prick test for Blatela germanica.
42	DENND1B	rs10494758	A/G	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10494758 was negatively associated with skin prick test for Blatela germanica.
43	DENND1B	rs34261593	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs34261593 was negatively associated with skin prick test for Blatela germanica.
44	DENND1B	rs6676073	A/C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs6676073 was negatively associated with skin prick test for Blatela germanica.
45	DENND1B	rs12731480	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs12731480 was negatively associated with skin prick test for Blatela germanica.
46	DENND1B	rs4915554	A/G	G	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs4915554 was negatively associated with skin prick test for Blatela germanica.
47	DENND1B	rs1775454	A/C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs1775454 was negatively associated with skin prick test for Blatela germanica.
48	DENND1B	rs2488394	A/C	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs2488394 was negatively associated with skin prick test for Blatela germanica.
49	DENND1B	rs3814321	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs3814321 was negatively associated with skin prick test for Blatela germanica.
50	DENND1B	rs2488409	A/C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs2488409 was negatively associated with skin prick test for Blatela germanica.
51	DENND1B	rs10442656	C/T	T	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10442656 was negatively associated with skin prick test for Blatela germanica.
52	DENND1B	rs10922255	C/T	C	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10922255 was negatively associated with skin prick test for Blatela germanica.
53	DENND1B	rs10737692	A/G/T	A	Intron Variant	Asthma, Atopy	Brazilian children	28668455	rs10737692 was negatively associated with skin prick test for Blatela germanica.
54	DAD1	rs1681577	G/T	G	Intron Variant	Asthma, Atopy	South American population	30032071	Significant association between G allele of DAD1 SNP rs1681577 and asthma was noted in South American population.
55	DAD1	rs1051101	A/C/G/T (REV)	C	5 Prime UTR Variant	Asthma, Atopy	South American population	30032071	Significant association between T allele of DAD1 SNP rs1051101 and spontaneous IL13 production was noted in South American population.
56	DAD1	rs3811189	C/G/T (REV)	T	Intron Variant	Asthma, Atopy	South American population	30032071	Significant association between C allele of DAD1 SNP rs3811189 and spontaneous IL13 production was noted in South American population.
57	DMRT1	rs3812523	C/G/T (REV)	T	2KB Upstream Variant	Childhood Asthma	-	26906082	Polymorphism in the testis-associated gene DMRT1 rs3812523 displayed interactions with sex on asthma status in a population of primarily clinically defined asthmatic children and nonasthmatic control subjects. Polymorphism rs3812523 located in the putative DMRT1 promoter was associated with allele-specific changes in transcription factor binding and promoter activity in vitro.
58	DYNAP	rs7240102	A/G	A	Intron Variant	Asthma Remission	-	29786918	rs7240102 was associated with clinical remission of asthma and rs7240102 was an eQTL for POL1.
59	D2HGDH	rs34290285	A/G	G	Non Coding Transcript Variant	Asthma, Allergic Diseases	European population	29785011	rs34290285 was associated with asthma and allergic diseases.
60	DECTIN1	rs7959451	C/T	C	Non Coding Transcript Variant	Allergic Bronchopulmonary Aspergillosis (ABPA)	Caucasian population	27708669	rs7959451 was associated with ABPA on the ABPA versus Atopic asthma model and on the ABPA versus Healthy model.
61	DYNC1H1	rs4906262	C/T	C	-	Asthma	-	27554816	rs4906262 is an eQTL for DYNC1H1 gene which is significantly associated with asthma risk.
62	DDX39B	rs2071595	A/C/G/T (REV)	C	Intron Variant	Asthma	-	27554816	rs2071595 is an eQTL for HCP5 gene which is significantly associated with asthma risk.
63	DUSP1	rs881152	A/C/G	G	2KB Upstream Variant	Asthma	Latino American population	20673984	rs881152 was significantly associated with bronchodilator responsiveness in asthma patients.
64	DUSP1	rs34507926	C/G/T (REV)	C	Intron Variant	Asthma	Latino American population, African American population	20673984	rs34507926 genotype was significantly associated with bronchodilator responsiveness in the asthmatics.
65	DUSP1	rs17075181	A/G	A	-	Atopic Dermatitis	European population	22445417	In silico analysis of genome wide single nucleotide polymorphism data revealed evidence of an association between Atopic Dermatitis and rs17075181 near DUSP1.
66	DCBLD2	rs16840208	C/T	C	Missense Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	A non-synonymous SNP rs16840208 (Asp723Asn) shows a strong association with FEV(1) decline in AERD patients.
67	DCBLD2	rs1371687	C/T (REV)	T	Intron Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs1371687 showed association with susceptibility to AERD.
68	DCBLD2	rs7615856	C/T	C	Intron Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs7615856 showed association with susceptibility to AERD.
69	DCBLD2	rs828621	A/T	T	Intron Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs828621 showed association with susceptibility to AERD.
70	DCBLD2	rs8833	C/T	C	3 Prime UTR Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs8833 showed association with susceptibility to AERD.
71	DCBLD2	rs828618	A/G	G	Intron Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs828618 showed association with susceptibility to AERD.
72	DCBLD2	rs828616	A/G	G	Synonymous Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs828616 showed association with susceptibility to AERD.
73	DCBLD2	rs1062196	A/G (REV)	G	3 Prime UTR Variant	Aspirin exacerbated respiratory disease (AERD)	Korean population	22468095	rs1062196 showed association with susceptibility to AERD.
74	DEFB1	rs5743399	C/T (REV)	C	-	Atopic Dermatitis	Korean population	19135873	The rs5743399 SNP and the CT haplotype in the DEFB1 gene were significantly associated with the susceptibility to Atopic Dermatitis.
75	DEFB1	rs5743409	C/G/T (REV)	G	2KB Upstream Variant	Atopic Dermatitis	Korean population	19135873	The rs5743409 SNP and the CT haplotype in the DEFB1 gene were significantly associated with the susceptibility to Atopic Dermatitis.
76	DNA5H	rs6554809	C/T	T	Intron Variant	Allergic Rhinitis	Han Chinese population	32082391	Significant Allergic Rhinitis risk was associated with rs6554809 in DNAH5.