Browse Result

Total number of records for in E of in DAAB (Version-2) database: 27

Record no	GENE NAME	SNP ID	CHANGES	ANCESTRAL ALLELES	FUNCTIONAL CONSEQUENCES	DISEASE	POPULATION	Pubmed ID	Comments
1	ESR1	rs1999805	C/T	C	Intron variant	Asthma	-	30448624	ESR1 SNP rs1999805 was associated with asthma suggesting that this SNP may be important in asthma pathogenesis.
2	ELF5	rs3910901	A/C/G	C	5' Upstream region of ELF5	Pediatric Asthma	Taiwanese population	25648666	SNP rs3910901 may have a minor impact on pediatric asthma in the Taiwanese population. The CC genotype was more frequent in asthma patients.
3	EDDM3B	rs3827907	C/T	T	3' UTR Variant	Asthma	African Americans	30367910	The rs3827907 C-allele appeared to particularly influence ICS treatment response in the presence of eosinophilic inflammation. The rs3827907 C-allele was associated with lower RNASE2 expression. rs3827907 was thus significantly associated with ICS-mediated changes in asthma control and was jointly associated with asthma exacerbations.
4	EPHX1	rs2740171	A/C	C	Intron Variant	Childhood Asthma	Asian population	29411558	EPHX1 AA genotype was associated with higher risk of asthma compared with the CC genotype.
5	eNOS	rs1799983	A/G/T	G	Missense Variant	Childhood Asthma	Mediterranean origin of population	27363984	In children with asthma, 894G>T polymorphism of the eNOS gene was correlated with sensitization to common seasonal aeroallergens.
6	eNOS	rs2070744	C/T	C	Intron Variant	Childhood Asthma	Mediterranean origin of population	27363984	In children with asthma, -786T/C polymorphism of the eNOS gene was correlated with sensitization to common seasonal aeroallergens.
7	ERBB2	rs4252665	C/T	C	500B Downstream Variant	Asthma, Rhino Conjunctivitis	Sicilian children	30646946	Current Asthma was strongly associated with rs4252665. The current asthma subjects had a high frequency of CT heterozygote genotype compared with controls, which were mostly homozygous.
8	ERAP1	rs26618	A/C/G/T	T	Missense Variant	Atopic Dermatitis	Polish population	30680818	ERAP1 Polymorphism Ile276Met (rs26618) is associated With Atopic Dermatitis and affects the generation of HLA-C associated antigenic epitope in vitro.
9	EMSY	rs7130588	A/G	A	-	Childhood Allergic Rhinitis	Chinese Han population	30170133	rs7130588-AG genotype in EMSY region was associated with a significantly increased risk of Allergic Rhinitis (AR) compared to the AA genotype, specific to moderate-to-severe AR. The rs7130588-G allele was only associated with a high risk of moderate-to-severe AR. A significantly increased Allergic Rhinitis risk was associated with the haplotype G-T-T (rs7130588-rs2155219-rs7927894).
10	EMSY	rs7927894	C/T	C	-	Childhood Allergic Rhinitis	Chinese Han population	30170133	rs7927894-CT genotype in EMSY region was associated with a significantly increased risk of Allergic Rhinitis (AR) compared to the CC genotype, specific to moderate-to-severe AR. A significantly increased Allergic Rhinitis risk was associated with the haplotype G-T-T (rs7130588-rs2155219-rs7927894).
11	EMSY	rs2155219	G/T	G	-	Childhood Allergic Rhinitis	Chinese Han population	30170133	A significantly increased Allergic Rhinitis risk was associated with the haplotype G-T-T (rs7130588-rs2155219-rs7927894).
12	EVI5	rs12743520	A/C	C	Intron Variant	Asthma, Allergic Diseases	European population	29785011	rs12743520 was associated with asthma and allergic diseases.
13	EGFR	rs4947972	A/C/G/T	G	Intron Variant	Allergy	-	20357714	EGFR gene polymorphism (rs4947972) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults.
14	EGFR	rs12718945	G/T	G	Intron Variant	Allergy	-	20357714	EGFR gene polymorphism (rs12718945) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults.
15	EGFR	rs2072454	C/T	C	Synonymous Variant	Allergy	-	20357714	EGFR gene polymorphism (rs2072454) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults.
16	EGFR	rs2227983	A/C/G/T	G	Missense Variant	Allergy	-	20357714	EGFR gene polymorphism (rs2227983) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults.
17	EGFR	rs2293347	A/G (REV)	G	Synonymous Variant	Allergy	-	20357714	EGFR gene polymorphism (rs2293347) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults.
18	EBI3	rs670188	A/C/G/T (REV)	T	2KB Upstream Variant	Allergic Rhinitis	Chinese population	26791767	rs670188 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy.
19	EBI3	rs393581	A/G (REV)	A	2KB Upstream Variant	Allergic Rhinitis	Chinese population	26791767	rs393581 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy.
20	EBI3	rs4740	A/G	G	Missense Variant	Allergic Rhinitis	Chinese population	26791767	rs4740 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy.
21	EBI3	rs353702	C/G/T	C	500B Downstream Variant	Allergic Rhinitis	Chinese population	26791767	rs353702 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy.
22	EPO	3979A/G	A/G	-	-	Allergic Rhinitis	Czech population	19439985	3979A/G single nucleotide polymorphism was marginally significantly associated with allergic rhinitis.
23	EPO	2649T/C	T/C	-	-	Allergic Rhinitis	Czech population	19439985	2649T/C was found to be in association with the allergic phenotype.
24	EPO	3097A/G	A/G	-	-	Allergic Rhinitis	Czech population	19439985	3097A/G was found to be in association with the allergic phenotype.
25	EGR1	rs7729723	A/G	G	-	Asthma	Chinese population	18507785	Significant associations were found between plasma total IgE concentration and -G4071A in asthmatic patients.
26	EGR1	rs11743810	C/T	-	Intron Variant	Asthma	Chinese population	18507785	Significant associations were found between plasma total IgE concentration and IVS1 -42 C> T in asthmatic patients.
27	EGR1	rs7729723	A/G	G	-	Allergic Rhinitis	Chinese population	19833116	Significant correlations were found between -4071 A>G with increased plasma total IgE and atopy in allergic rhinitis patients.