Browse Result

Total number of records for in H of in DAAB (Version-2) database: 29

Record no	GENE NAME	SNP ID	CHANGES	ANCESTRAL ALLELES	FUNCTIONAL CONSEQUENCES	DISEASE	POPULATION	Pubmed ID	Comments
1	HLA-G	rs1710	C/G	-	3 Prime UTR Variant	Asthma	Brazilian population	30142579	The +3010C allele was overrepresented in mild asthma patients when compared to controls. The +3010G allele was overrepresented in severe asthma patients in comparison to patients with mild asthma. The +3010C/G HLA-G 3'UTR variation site was differentially associated according to asthma severity.
2	HLA-G	rs1063320	A/C/G	C	3 Prime UTR Variant	Asthma	Brazilian population	30142579	The +3142G allele was overrepresented in mild asthma patients when compared to controls. The +3142C allele was overrepresented in severe asthma patients in comparison to patients with mild asthma. The +3142C/G HLA-G 3'UTR variation site was differentially associated according to asthma severity.
3	HCG22	rs2523870	A/G	A	-	Late onset Asthma	Japanese population	26830115	rs2523870 was strongly correlated with increased expression of HCG22 and confer increased risk of late-onset asthma.
4	HCG22	rs2517548	A/G	A	-	Late onset Asthma	Japanese population	26830115	rs2517548 was strongly correlated with increased expression of HCG22 and confer increased risk of late-onset asthma.
5	HRH1	-	-	-	-	Allergic Rhinitis	Chinese Han population	30168182	Patients with CT, TT, or CT+TT genotype increased the risk of Allergic Rhinitis incidence in the −17C/T site of HRH1 gene. HRH1 gene polymorphisms may correlate with oral H1‐antihistamine efficacy for the treatment of patients with Allergic Rhinitis (AR), which can be used as a biological indicator of the prediction of therapeutic efficacy of patients with AR.
6	HLA-DQA1	rs9272346	A/G	A	2KB Upstream Variant	Asthma	European Ancestry	27130862	rs9272346 in 6p21 loci was found to be associated with time to asthma onse (TAO) at genome-wide significance levels.
7	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB103 was positively associated with risk of asthma. DRB103 was associated with asthma in whites. DRB1*03 was associated with asthma in children.
8	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB115 was negatively associated with risk of asthma. DRB115 was associated with asthma in whites. DRB1*15 was associated with asthma in children.
9	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB1*07 was associated with asthma in Asians.
10	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB1*14 was associated with asthma in Asians.
11	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB1*04 was associated with asthma in children.
12	HLA-DRB1	-	-	-	-	Asthma	-	27503745	DRB1*09 was associated with asthma in children.
13	HSPA12B	rs910652	A/G (REV)	A	Intron Variant	Asthma	European population	27387956	The interaction of rs910652 and rs11684871 was associated with asthma susceptibility.
14	HRH4	-	C/T	-	-	Childhood Asthma	African American population	28101058	There was association between HRH4 413 C/T and histamine pharmacodynamic response in children with asthma.
15	HNMT	-	C/T	-	-	Childhood Asthma	African American population	28101058	There was association between HNMT-1639 C/T and histamine pharmacodynamic response in children with asthma.
16	HLA-DP	rs987870	C/T (REV)	T	Intron Variant	Asthma	Dutch population	27439200	The risk allele G of rs987870 was significantly associated with asthma.
17	HACE1, LINC00577, LIN28B	rs13437006	A/C/G	G	-	Childhood Asthma	Puerto Rican population, Mexican population, African American population	29509491	The C allele of rs13437006 was significantly associated with bronchodilator drug response (BDR) in asthmatic children.
18	HACE1, LINC00577, LIN28B	rs6926020	C/T	T	-	Childhood Asthma	Puerto Rican population, Mexican population, African American population	29509491	The C allele of rs6926020 was significantly associated with bronchodilator drug response (BDR) in asthmatic children.
19	HLA-DQB1	rs9273374	A/G/T	A	2KB Upstream Variant	Asthma, Allergic Diseases	European population	29785011	rs9273374 was associated with asthma and allergic diseases.
20	HV745896	rs12413578	C/G/T	C	-	Asthma, Allergic Diseases	European population	29785011	rs12413578 was associated with asthma and allergic diseases.
21	HLA-DQB1	rs1063355	A/C (REV)	A	3 Prime UTR Variant	Asthma	-	27554816	rs1063355 is an eQTL for HLA-DQB1 gene which is significantly associated with asthma risk.
22	HLA-DQB1	rs1063355	A/C (REV)	A	3 Prime UTR Variant	Asthma	-	27554816	rs1063355 is an eQTL for LIMS1 gene which is significantly associated with asthma risk.
23	HLA-DQB1-AS1	rs6928482	C/T	T	2KB Upstream Variant	Asthma	-	27554816	rs6928482 is an eQTL for TAP1 gene which is significantly associated with asthma risk.
24	HIBADH	rs6951856	A/C	C	-	Asthma	-	27554816	rs6951856 is an eQTL for HIBADH gene which is significantly associated with asthma risk.
25	HLA-DQA1	rs504594	A/G/T (REV)	-	-	Asthma	-	27554816	rs504594 is an eQTL for HLA-DQA1 gene which is significantly associated with asthma risk.
26	HLA-DQB1	rs9273373	A/G	A	2KB Upstream Variant	Asthma with Hay Fever	European population, American population, Australian population	24388013	The rs9273373:G allele was associated with increased asthma with hay fever risk.
27	HRH4	rs77485247	A/T	T	2KB Upstream Variant	Allergic Rhinitis	Chinese population	27888642	HRH4 rs77485247 polymorphism may be associated with the risk of Allergic Rhinitis.
28	HRH4	rs77041280	A/C/T	A	Missense Variant	Allergic Rhinitis	Chinese population	27888642	HRH4 rs77041280 polymorphism may be associated with the risk of Allergic Rhinitis.
29	HLA	rs7775228	C/T	T	-	Allergic Rhinitis	Han Chinese population	32082391	Significant Allergic Rhinitis risk was associated with rs7775228 in HLA region.