| Record no | GENE NAME | SNP ID | CHANGES | ANCESTRAL ALLELES | FUNCTIONAL CONSEQUENCES | DISEASE | POPULATION | Pubmed ID | Comments |
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| 1 | LINC01149 | rs2596464 | A/G | A | Intron Variant | Childhood Asthma | Non-Hispanic white (NHW) population, African American (AA) population | 30373671 | The variant (rs2596464) showed association with childhood asthma in NHWs and AAs. |
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| 2 | LPHN1 | rs3810256 | C/T | C | 3 Prime UTR Variant | Asthma | - | 27325752 | The minor allele of the single nucleotide polymorphism (rs3810256) in LPHN1 was associated with asthma and with increased LPHN1 expression in lung tissue. |
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| 3 | LYN | rs112735328 | A/G | G | - | Childhood Asthma | Puerto Rican children | 28574721 | LYN SNP rs112735328 was associated with the total number of Skin Test Reactivity. |
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| 4 | LEP | rs11763517 | C/T | T | Intron Variant | Childhood Asthma | European population | 27186323 | The interaction of cg00666422 and rs11763517 (CT vs TT and CC) was associated with FEV1, FEV1/FVC ratio and FEF25-75% in asthmatics such that they decreased with increasing DNA methylation. |
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| 5 | LEPR | rs1137101 | A/G | A | Missense Variant | Occupational Bronchial Asthma | - | 30351648 | Polymorphism of Gln223Arg gene of Leptin receptor (LEPR) are associated with higher activity of inflammation and therefore with increased risk of occupational bronchial asthma associated with metabolic syndrome and diabetess mellitus 2 type. |
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| 6 | LRRC3C | rs8079416 | C/T | T | Intron Variant | Asthma, Rhino Conjunctivitis | Sicilian children | 30646946 | Rhino Conjunctivitis was modestly associated with rs8079416. rs8079416 showed high frequencies of heterozygote genotypes in Rhino Conjunctivitis patients as compared with control subjects, which are frequently homozygous. |
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| 7 | LOC10192956, ATF3 | rs1001304 | A/G (REV) | G | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs1001304, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 8 | LEP | rs13228377 | A/C/G | A | 2KB Upstream Variant | Childhood Asthma | Caucasian population | 30203371 | LEP polymorphism may increase asthma risk via influence on its serum level. |
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| 9 | LTA | rs2844484 | C/T (REV) | C | Intron Variant | Atopic Dermatitis | Greenlandic population | 28740106 | Within the Greenlandic population, Inuit with LTα rs2844484 homozygous CC had a signifcantly lower prevalence of dermatitis compared with Inuit with CT genotype. |
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| 10 | LTA | rs2844484 | C/T (REV) | C | Intron Variant | Bronchitis | Danish population | 28740106 | LTA SNP rs2844484 was signifcantly associated with bronchitis within the Danish population. |
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| 11 | LTA | rs909253 | A/C/T (REV) | T | Intron Variant | Bronchitis | Danish population | 28740106 | Significant associations of LTA rs909253 with bronchitis in Danish Inuit was observed. |
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| 12 | LTA | rs1041981 | A/C | C | Missense Variant | Bronchitis | Danish population | 28740106 | Significant associations of LTA rs1041981 with bronchitis in Danish Inuit was observed. |
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| 13 | LEPR | rs10493380 | A/C | A | Intron Variant | Asthma (Acetaminophen asthma association) | Population from Isle of Wight and Kuwait | 30231898 | There was a “sex × acetaminophen use” interaction on a multiplicative scale among participants carrying the AC or CC genotypes of rs10493380. There was no evidence for a “sex × acetaminophen use” interaction on a multiplicative scale among subjects with the AA genotype. |
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| 14 | LEPR | rs8179183 | C/G/T | G | Missense Variant | Asthma (Acetaminophen asthma association) | Population from Isle of Wight and Kuwait | 30231898 | The sex-related modifications and acetaminophen use in relation to asthma was present only among participants who carried one or two copies of the LEPR SNP (rs8179183) minor alleles. |
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| 15 | LEPR | rs3828034 | C/T (REV) | T | Intron Variant | Asthma (Acetaminophen asthma association) | Population from Isle of Wight and Kuwait | 30231898 | The sex-related modifications and acetaminophen use in relation to asthma was present only among participants who carried one or two copies of the LEPR SNP (rs3828034) minor alleles. |
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| 16 | LEPR | rs17415296 | A/C | C | Intron Variant | Asthma (Acetaminophen asthma association) | Population from Isle of Wight and Kuwait | 30231898 | Among those carrying at least one copy of the minor allele for LEPR SNP (rs17415296), the magnitude of the acetaminophen use effect on asthma was highly pronounced among males but not among females. |
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| 17 | LOC105376110 | rs73650726 | A/G | A | Intron Variant | Asthma | African American population | 30206298 | rs73650726 on Chromosome 9q21 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 18 | LINC02220 | rs17834628 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | rs17834628 was significantly associated with bronchodilator drug response (BDR) in racially diverse asthmatic children. |
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| 19 | LINC02220 | rs35661809 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | rs35661809 was significantly associated with bronchodilator drug response (BDR) in racially diverse asthmatic children. |
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| 20 | LINC02220 | rs17237639 | A/G/T | A | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The G allele of rs17237639 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 21 | LINC02220 | rs1017452 | A/G | A | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The G allele of rs1017452 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 22 | LINC02220 | rs1017454 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The A allele of rs1017454 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 23 | LINC02220 | rs1017453 | C/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The C allele of rs1017453 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 24 | LINC02220 | rs17237443 | A/C/T | T | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The C allele of rs17237443 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 25 | LINC02220 | rs17833938 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The A allele of rs17833938 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 26 | LINC02220 | rs34845041 | C/T | C | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The T allele of rs34845041 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 27 | LINC02220 | rs1017451 | A/C/T | C | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The T allele of rs1017451 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 28 | LINC02220 | rs62347395 | A/G | A | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The G allele of rs62347395 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 29 | LINC00613, PCDH18 | rs17048684 | A/T | T | - | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The A allele of rs17048684 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 30 | LINC02220 | rs1438293 | A/G | A | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The G allele of rs1438293 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 31 | LOC101928387 | rs66544720 | C/T | C | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The T allele of rs66544720 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 32 | LOC101928387 | rs7313907 | C/G | G | Non Coding Transcript Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The C allele of rs7313907 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 33 | LOC101928387 | rs11044754 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The A allele of rs11044754 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 34 | LOC107986606 | rs13200833 | A/G | G | Intron Variant | Childhood Asthma | Puerto Rican population, Mexican population, African American population | 29509491 | The A allele of rs13200833 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. |
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| 35 | LINC00299 | rs10174949 | A/G | G | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs10174949 was associated with asthma and allergic diseases. |
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| 36 | LOC101927770 | rs2766664 | A/G/T | G | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs2766664 was associated with asthma and allergic diseases. |
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| 37 | LRRC3C | rs7207600 | A/G/T | A | Intron Variant | Asthma | - | 27554816 | rs7207600 is an eQTL for IKZF3 gene which is significantly associated with asthma risk. |
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| 38 | LTA | rs13215091 | A/G | A | Intron Variant | Asthma | - | 27554816 | rs13215091 is an eQTL for HSPA1B gene which is significantly associated with asthma risk. |
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| 39 | LOC105379664 | rs2442752 | A/G (REV) | A | Intron Variant | Asthma | - | 27554816 | rs2442752 is an eQTL for LTA gene which is significantly associated with asthma risk. |
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| 40 | LRRC32 | rs2155219 | G/T | T | - | Asthma with Hay Fever | European population, American population, Australian population | 24388013 | The rs2155219:T allele was associated with increased asthma with hay fever risk. |
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| 41 | LRRC32 | rs1320644 | C/T (REV) | C | Non Coding Transcript Variant | Asthma with Hay Fever | European population, American population, Australian population | 24388013 | rs1320644 was associated with asthma with hay fever risk at a suggestive significance level. |
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| 42 | LELP1 | rs7534334 | C/T | T | 500B Downstream Variant | Atopic Dermatitis | Polish population | 26608070 | rs7534334 SNP located in the LELP1 region, may be a potential genetic marker for the risk and course of atopic dermatitis. |
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| 43 | LTA4H | rs1978331 | C/T (REV) | C | Intron Variant | Asthma and Allergy | Caucasian population | 18547289 | An association between SNP rs1978331 (LTA4H) and asthma and/or related phenotypes was observed. |
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| 44 | LPP | rs9865818 | A/G | A | Intron Variant | Allergic Rhinitis | Han Chinese population | 32082391 | Significant Allergic Rhinitis risk was associated with rs9865818 in LPP. |
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