| Record no | GENE NAME | SNP ID | CHANGES | ANCESTRAL ALLELES | FUNCTIONAL CONSEQUENCES | DISEASE | POPULATION | Pubmed ID | Comments |
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| 1 | RAD50 | rs3798134 | C/T | C | Intron variant | Asthma | - | 27050946 | rs3798134 in RAD50 was correlated with the expression levels of IL13 and the expression levels of IL13 was correlated with asthma in BAL. |
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| 2 | RAD50 | rs2244012 | T/C | T | Intron variant | Asthma | - | 27050946 | rsrs2244012 is associated with asthma. |
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| 3 | RORA | rs10162630 | A/G | G | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs10162630 was significantly associated with atopy. rs10162630 was associated with SPT and sIgE for D. pteronyssinus and/or B. tropicalis. The A alele of rs10162630 was associated with high levels of IL-13 production by Blomia tropicalis stimulus. |
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| 4 | RORA | rs11071584 | A/C/T | A | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs11071584 was significantly associated with atopy. The A allele of rs11071584 had a negative association with sIgE and SPT for Periplanata americana. |
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| 5 | RORA | rs12903172 | A/C/T | T | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs12903172 was significantly associated with atopy. A positive association was observed between rs12903172 with SPT for cockroaches. |
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| 6 | RORA | rs17191519 | A/G | A | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs17191519 was significantly associated with atopy. A positive association was observed between the G allele of rs17191519 with sIgE and SPT for house dust mites. Atopic individuals with rs17191519 AG/GG genotypes exhibited higher IL-5 production upon stimulation with Dermatophagoides pteronyssinus, when compared to individuals with rs17191519 AA genotype. |
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| 7 | RORA | rs2414681 | A/C | C | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs2414681 was significantly associated with atopy. A positive association was observed between rs2414681 with SPT for Blioma tropicalis. The allele A of rs2414681 was negatively associated with asthma. |
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| 8 | RORA | rs17270243 | A/G | A | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs17270243 was significantly associated with atopy. A positive association was observed between the G allele of rs17270243 with sIgE for house dust mites and SPT for Blioma tropicalis. rs17270243 was significantly associated with expression of the RORA gene in lung tissue. |
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| 9 | RORA | rs34720147 | C/T | C | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs34720147 was significantly associated with atopy. A positive association was observed between rs34720147 with sIgE for Blatella germanica and SPT for Periplanata americana. |
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| 10 | RORA | rs4775301 | C/T/G | T | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs4775301 was significantly associated with atopy. A positive association was observed between rs4775301 with sIgE for Blatella germanica and SPT for house dust mites. |
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| 11 | RORA | rs55796775 | G/T | G | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs55796775 was significantly associated with atopy. A positive association was observed between rs55796775 with sIgE for Dermatophagoides pteronyssinus and SPT for house dust mites. The T allele of rs55796775 was positively associated with IL-13 production upon D. pteronyssinus stimulation in peripheral blood cells. |
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| 12 | RORA | rs7169281 | A/C/T | T | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs7169281 was significantly associated with atopy. A positive association was observed between rs726914 with SPT for Dermatophagoides pteronyssinus. The allele C of rs7169281 was negatively associated with asthma. This SNV was also associated with non-atopic asthma. |
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| 13 | RORA | rs726914 | A/C/G | G | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs726914 was significantly associated with atopy. A positive association was observed between rs726914 with SPT for cockroaches and sIgE for Blomia tropicalis and Blatella germanica. |
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| 14 | RORA | rs8024133 | C/T | C | Intron Variant | Asthma and Atopy | Latin American population | 30539779 | rs8024133 was significantly associated with atopy. A positive association was observed between rs8024133 with SPT for house dust mites. |
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| 15 | RORA | rs11071559 | C/T | C | Intron Variant | Pediatric Asthma | Chinese Zhuang population | 29282706 | RORA rs11071559C>T polymorphism was associated with an elevated susceptibility to pediatric asthma in the Chinese Zhuang population. |
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| 16 | RORA | rs11071559 | C/T | C | Intron Variant | Asthma | European Ancestry | 27130862 | rs11071559 in 15q22 loci was associated with time to asthma onse (TAO) at suggestive significance levels. |
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| 17 | RORA | rs2899662 | C/T | C | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs2899662 with NPSR1 SNPs rs887020, rs963218, rs324396, rs324384, rs324957 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 18 | RORA | rs8042149 | G/T | T | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs8042149 with NPSR1 SNP rs714588 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 19 | RORA | rs4775301 | C/G/T | T | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs4775301 with NPSR1 SNPs rs714588, rs324396 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 20 | RORA | rs12591848 | A/C | C | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs12591848 with NPSR1 SNPs rs963218, rs2530547 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 21 | RORA | rs4775289 | A/C | C | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs4775289 with NPSR1 SNPs rs963218, rs740347 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 22 | RORA | rs11071561 | A/T | A | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs11071561 with NPSR1 SNP rs727162 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 23 | RORA | rs7171681 | C/T | T | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs7171681 with NPSR1 SNP rs963218, rs324396 affect the risk for asthma. RORA* NPSR1 interactions appear to be involved in mechanisms specific for nocturnal asthma. |
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| 24 | RORA | rs4775292 | C/T | C | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs4775292 with NPSR1 SNP rs1379928 affect nocturnal asthma symptoms. |
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| 25 | RORA | rs12437690 | A/G | A | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs12437690 with NPSR1 SNP rs1379928 affect nocturnal asthma symptoms. |
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| 26 | RORA | rs17204454 | A/C/T | A | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs17204454 with NPSR1 SNP rs1379928 affect nocturnal asthma symptoms. |
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| 27 | RORA | rs341382 | C/T | T | Intron Variant | Nocturnal Asthma | - | 30927345 | Interaction of RORA SNP rs341382 with NPSR1 SNP rs324396 affect nocturnal asthma symptoms. |
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| 28 | RPL34P18, CDH17 | rs2446824 | A/G (REV) | A | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2446824, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 29 | RPL34P18, CDH17 | rs2446823 | A/C (REV) | A | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2446823, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 30 | RPL34P18, CDH17 | rs149630836 | - | - | Intergenic Deletion | Diisocyanate Induced Asthma | European population | 29969634 | rs149630836, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 31 | RPL34P18, CDH17 | rs2513788 | G/T | T | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2513788, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 32 | RPL34P18, CDH17 | rs2513789 | A/G | A | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2513789, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 33 | RPL34P18, CDH17 | rs2513790 | C/T | C | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2513790, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 34 | RPL34P18, CDH17 | rs2446821 | A/C (REV) | C | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2446821, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 35 | RPL34P18, CDH17 | rs2513791 | A/C | C | Intergenic Variant | Diisocyanate Induced Asthma | European population | 29969634 | rs2513791, associated with Diisocyanate Induced Asthma is considered most likely to function by altering gene regulatory mechanism in disease relevant cells. |
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| 36 | RELA | rs931127 | A/G | G | - | Adult onset Asthma | European population | 27504716 | rs931127 in RELA was marginally associated with asthma. Near RELA, the risk of current adult-onset asthma was increased in G carriers of rs931127 among Low Molecular Weight Agents and Irritants exposed participants. |
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| 37 | RELA | rs7949980 | C/T | C | - | Adult onset Asthma | European population | 27504716 | Near RELA, the risk of current adult-onset asthma was increased in T carriers of rs7949980 among Low Molecular Weight Agents and Irritants exposed participants. |
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| 38 | RAD50 | rs2706362 | C/T | C | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs2706362 was associated with asthma and allergic diseases. |
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| 39 | RTEL1 | rs3208007 | C/G/T | C | Synonymous Variant | Asthma, Allergic Diseases | European population | 29785011 | rs3208007 was associated with asthma and allergic diseases. |
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| 40 | RERE | rs301805 | A/C (REV) | C | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs301805 was associated with asthma and allergic diseases. |
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| 41 | RUNX3 | rs742230 | C/T (REV) | T | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs742230 was associated with asthma and allergic diseases. |
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| 42 | RAD51B | rs8008961 | C/T | C | Intron Variant | Asthma, Allergic Diseases | European population | 29785011 | rs8008961 was associated with asthma and allergic diseases. |
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| 43 | REEP3 | rs7898489 | C/T | T | 3 Prime UTR Variant | Asthma | - | 27554816 | rs7898489 is an eQTL for REEP3 gene which is significantly associated with asthma risk. |
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| 44 | RORA | rs1898413 | A/G | A | Intron Variant | Allergic Rhinitis | Han Chinese population | 26196693 | rs1898413 in RORA was significantly associated with Allergic Rhinitis. |
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| 45 | RAB31 | rs591067 | A/C/T (REV) | T | - | Atopic Dermatitis | European population | 22445417 | In silico analysis of genome wide single nucleotide polymorphism data revealed evidence of an association between Atopic Dermatitis and rs591067 near RAB31. |
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| 46 | RAB31 | rs587351 | G/T (REV) | G | - | Atopic Dermatitis | European population | 22445417 | In silico analysis of genome wide single nucleotide polymorphism data revealed evidence of an association between Atopic Dermatitis and rs587351 near RAB31. |
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| 47 | RAB31 | rs684949 | C/G/T (REV) | T | - | Atopic Dermatitis | European population | 22445417 | In silico analysis of genome wide single nucleotide polymorphism data revealed evidence of an association between Atopic Dermatitis and rs684949 near RAB31. |
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