SNP data of: Disease - Atopic Dermatitis (AD) and
Biological sample - Blood
| SL. No. | Gene Name | SNP Involved | Comments | Reference (PMID) |
| 1 | STAT1 | rs3771300 | The polymorphism C39134A (rs3771300), located in a potentially cis acting regulatory element in STAT1 intron 24, was inversely related to atopy measured by skin prick test, total and specific serum IgE levels. STAT1 SNP C39134A may protect from atopic sensitization. | 17983380 |
| 2 | TSLP | rs2289278 | The TSLP rs2289278 CC genotype increased the risk of Atopic Dermatitis (AD). In children sensitized to certain allergens, a genetic predisposition (rs2289278 genotype CC) significantly increased the risk of AD. | 26712523 |
| 3 | TSLP | rs2289278 | The rs2289278 C allele significantly increased the risk of developing asthma in Atopic Dermatitis patients. | 26712523 |
| 4 | IL10 | rs1800871 | The IL-10-819G/A polymorphism seems to be associated with increased risk of Atopic Dermatitis among Caucasian populations. | 30932690 |
| 5 | IL10 | rs1800896 | The IL10-1082G/A polymorphism (rs1800896) seems to be correlated with Atopic Dermatitis among Asian populations. | 30932690 |
| 6 | IL10 | rs1800872 | Patients with Atopic Dermatitis had a significantly lower frequency of the combined homozygous CC genotype and heterozygous AC genotype group of IL10 rs1800872 (-592A>C) as compared with Non atopic eczema patients. | 17188628 |
| 7 | IL10 | rs1800896 | IL10 rs1800896 (−1082 G/A) polymorphism is associated with the susceptibility and can be a risk factor for Atopic Dermatitis. | 29887728 |
| 8 | IL10 | rs1800871 | Patients with Atopic Dermatitis and non atopic eczema had a significantly lower frequency of the combined homozygous TT genotype and heterozygous CT genotype group of IL-10 rs1800871 (-819T>C) as compared with controls. | 17188628 |
| 9 | IL10 | rs1800896 | Atopic Dermatitis patients carrying G allele in rs1800896 (-1082 G/A) IL10 polymorphism are predisposed to higher serum concentration of IL10. | 25624864 |
| 10 | IL10 | rs1800896 | The presence of homozygous variant IL10 G1082A--AA in 80% cases characterizes early disease development, i.e. within 3 years after the first exposure to the occupational factor. | 26515179 |
| 11 | CCL5 | -401 G/A | A higher frequency of -401A was observed in individuals of African descent compared with Caucasian subjects. The mutant allele was associated with atopic dermatitis in children of the German Multicenter Allergy Study, but not with asthma. | 10640782 |
| 12 | CCL5 | -401 G/A | The RANTES promoter -401A polymorphism plays a role in the development of Atopic Dermatitis by up regulating serum levels of RANTES in Japanese patients. | 16046258 |
| 13 | GATA3 | rs10795656 | rs10795656 was associated with asthma and allergic diseases. | 29785011 |
| 14 | OXA1L | rs17619 | Significant association between A allele of OXA1L SNP rs17619 and production of IFNG stimulated with Blomia tropicalis was noted in South American population. | 30032071 |
| 15 | OXA1L | rs8572 | Significant association between G allele of OXA1L SNP rs8572 with positive skin prick test for dog epithelium, Periplanata americana, Dermatophagoides pteronyssinus and specific IgE for Dermatophagoides pteronyssinus was noted in South American population. | 30032071 |
| 16 | IL13 | G4257A | IL13 gene polymorphism G4257A is associated with susceptibility to atopic dermatitis in Japanese patients. | 12413765 |
| 17 | IL13 | rs1800925 | There is a significant role of -1112 C/T IL13 gene polymorphism in the pathogenesis of Atopic Dermatitis. | 23317483 |
| 18 | IL13 | rs20541 | The association between cesarean delivery and Atopic Dermatitis was significantly modified by parental history of allergic diseases or risk-associated IL13 (rs20541) and CD14 (rs2569190) genotypes. There was a trend of interaction between IL13 (rs20541) and delivery mode with respect to the subsequent risk of Atopic Dermatitis. | 24848505 |
| 19 | IL13 | rs20541 | The IL13 130Gln allele was associated with atopy and with atopic dermatitis. The IL13 Arg130Gln polymorphism and haplotypes consisting of IL13 Arg130Gln and IL4 C-589 T were associated with the development of atopy and atopic dermatitis. | 12847555 |
| 20 | IL13 | G4257A | An IL13 coding region variant (G4257A) is associated with a high total serum IgE level and Atopic Dermatitis in the German multicenter atopy study. | 10887320 |
| 21 | ADCY9 | rs2601796 | rs2601796 was significantly associated with skin prick test for Dermatophagoides pteronyssinus. | 28076799 |
| 22 | ADCY9 | rs2601814 | rs2601814 was significantly associated with skin prick test for Periplaneta americana, Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 23 | ADCY9 | rs2283497 | rs2283497 was significantly associated with skin prick test for Periplaneta americana, Dermatophagoides pteronyssinus or atleast one of the allergen tested. rs2283497 was significantly associated with sIgE for Blomia tropicalis and Dermatophagoides pteronyssinus. | 28076799 |
| 24 | ADCY9 | rs8061182 | rs8061182 was significantly associated with skin prick test for Blomia tropicalis, Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 25 | ADCY9 | kgp12201986 | kgp12201986 was positively associated with allergy in asthmatic patients. kgp12201986 was significantly associated with skin prick test for Periplaneta americana, Blomia tropicalis, Dermatophagoides pteronyssinus or atleast one of the allergen tested. kgp12201986 was also significantly associated sIgE for Blomia tropicalis or atleast one of the allergen tested. | 28076799 |
| 26 | ADCY9 | rs432166 | rs432166 was significantly associated with sIgE for Blomia tropicalis or atleast one of the allergen tested. | 28076799 |
| 27 | ADCY9 | rs2601777 | rs2601777 was significantly associated with sIgE for Blomia tropicalis or atleast one of the allergen tested. | 28076799 |
| 28 | ADCY9 | rs6500567 | rs6500567 was significantly associated with skin prick test for Periplaneta americana or atleast one of the allergen tested. rs6500567 was significantly associated with sTgE for Dermatophagoides pteronyssinus. | 28076799 |
| 29 | ADCY9 | rs4785953 | rs4785953 was significantly associated with sIgE for Blomia tropicalis and Dermatophagoides pteronyssinus. | 28076799 |
| 30 | ADCY9 | rs2444217 | rs2444217 was significantly associated with sIgE for Blomia tropicalis. rs2444217 was significantly associated with skin prick test for Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 31 | ADCY9 | rs8045426 | rs8045426 was significantly associated with sIgE for Blomia tropicalis. rs8045426 was significantly associated with unstimulated IL5 and IL13 production. | 28076799 |
| 32 | ADCY9 | rs7196832 | rs7196832 was significantly associated with skin prick test for cat epithelium. rs7196832 was significantly associated with unstimulated IL5 production. | 28076799 |
| 33 | ADCY9 | rs2108987 | rs2108987 was significantly associated with skin prick test for dog epithelium and Blatella germanica. rs2108987 was significantly associated with unstimulated IL5 production. | 28076799 |
| 34 | ADCY9 | rs2239313 | rs2239313 was significantly associated with skin prick test for Periplaneta americana, Blomia tropicalis, Dermatophagoides pteronyssinus, dog epithelium or atleast one of the allergen tested. | 28076799 |
| 35 | ADCY9 | rs4785951 | rs4785951 was significantly associated with skin prick test for Periplaneta americana, Dermatophagoides pteronyssinus, dog epithelium or atleast one of the allergen tested. | 28076799 |
| 36 | ADCY9 | rs13337675 | rs13337675 was significantly associated with skin prick test for Blatella germanica. | 28076799 |
| 37 | ADCY9 | rs2601798 | rs2601798 was significantly associated with skin prick test for Blatella germanica. rs2601798 was significantly associated with unstimulated IL5 production. | 28076799 |
| 38 | ADCY9 | rs61042195 | rs61042195 was significantly associated with skin prick test for Blomia tropicalis and Dermatophagoides pteronyssinus. | 28076799 |
| 39 | ADCY9 | rs2601807 | rs2601807 was significantly associated with skin prick test for Blomia tropicalis, Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 40 | ADCY9 | rs2531995 | rs2531995 was significantly associated with skin prick test for Periplaneta americana, Blomia tropicalis, Dermatophagoides pteronyssinus or atleast one of the allergen tested. rs2531995 was significantly associated with unstimulated IL13 production. | 28076799 |
| 41 | ADCY9 | rs409963 | rs409963 was significantly associated with skin prick test for Periplaneta americana or atleast one of the allergen tested. | 28076799 |
| 42 | ADCY9 | rs2532019 | rs2532019 was significantly associated with skin prick test for Periplaneta americana and Dermatophagoides pteronyssinus. | 28076799 |
| 43 | ADCY9 | rs9922384 | rs9922384 was significantly associated with skin prick test for Periplaneta americana and Dermatophagoides pteronyssinus. | 28076799 |
| 44 | ADCY9 | rs2058166 | rs2058166 was significantly associated with skin prick test for Periplaneta americana, Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 45 | ADCY9 | rs2601831 | rs2601831 was significantly associated with skin prick test for Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 46 | ADCY9 | rs79964474 | rs79964474 was significantly associated with skin prick test for Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 47 | ADCY9 | rs73490519 | rs73490519 was significantly associated with skin prick test for Dermatophagoides pteronyssinus or atleast one of the allergen tested. | 28076799 |
| 48 | ADCY9 | rs1045476 | rs1045476 was significantly associated with skin prick test for Dermatophagoides pteronyssinus and unstimulated IL13 production. | 28076799 |