SNP data of: Disease - Asthma and
Biological sample - CD4 T Cells
| SL. No. | Gene Name | SNP Involved | Comments | Reference (PMID) |
| 1 | RUNX3 | rs742230 | rs742230 was associated with asthma and allergic diseases. | 29785011 |
| 2 | STAT1 | rs3771300 | The polymorphism C39134A (rs3771300), located in a potentially cis acting regulatory element in STAT1 intron 24, was inversely related to atopy measured by skin prick test, total and specific serum IgE levels. STAT1 SNP C39134A may protect from atopic sensitization. | 17983380 |
| 3 | STAT6 | GT polymorphism | S allele (GT13 and GT14) of the GT repeat polymorphism confers significant risks to asthma. | 23861779 |
| 4 | STAT6 | rs71802646 | Short GT repeats of rs71802646 in STAT6 contribute to higher risk for asthma. | 24952213 |
| 5 | STAT6 | rs324015 | rs324015 may have a protective effect on atopic asthma. | 24952213 |
| 6 | STAT6 | rs1059513 | rs1059513 was associated with asthma and allergic diseases. | 29785011 |
| 7 | STAT6 | rs3024974 | STAT6 C1570T polymorphism may influence lung function growth in asthmatic children. | 17883727 |
| 8 | FOXP3 | rs56066773 | The mutated allele of 7340C>T was significantly associated with the simultaneous presence of autoimmunity and atopy in male children. | 25982578 |
| 9 | FOXP3 | rs2232367 | A significant increase in the frequency of the mutated allele of 1651C>T in the male control group as compared to patients with atopy and autoimmunity. | 25982578 |
| 10 | GATA3 | rs10795656 | rs10795656 was associated with asthma and allergic diseases. | 29785011 |
| 11 | GATA3 | rs422628 | cg17124583 modified the association of SNP rs422628 with asthma risk at the age of 18 years. Subjects with genotype AG showed an increase in average risk ratio from 0.31 to 11.65 when methylation level increased from 0.02 to 0.12, relative to genotype AA | 25250096 |
| 12 | GATA3 | rs1269486 | The interaction between Oral Contraceptive Pill (OCP) use and SNP rs1269486 was found to be associated with the methylation level of cg17124583 in asthma. | 25250096 |
| 13 | NFKB1 | rs28450894 | The T allele of rs28450894 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. The low BDR associated T allele of NFKB1 (rs28450894) is found predominantly among African populations. The low BDR associated T allele of rs28450894 is significantly associated with decreased expression of SLC39A8 in blood. | 29509491 |
| 14 | NFKB1 | rs4648006 | The T allele of rs4648006 was significantly associated with bronchodilator drug response (BDR) in asthmatic children. | 29509491 |
| 15 | IL17RB | rs3733072 | A rare allele of IL17RB +5661G>A may have a protective role against the development of asthma via regulation at the level of transcription. | 19118269 |
| 16 | IFNG | rs2430561 | The allelic frequencies of the AA genotypes in IFNG at +874 is associated with an increased risk of asthma in the Chinese Han adult population. | 24995662 |
| 17 | IFNG | CA repeat polymorphism | IFNG CA repeat polymorphism confer genetic susceptibility to atopic asthma in Japanese children. | 11240951 |
| 18 | IFNG | CA repeat polymorphism | CA14 occurrence in the first intron of IFNG can increase the risk of asthma in the Japanese population. | 24995662 |
| 19 | IFNG | rs1861494 | rs1861494 A/G polymorphism was associated with asthma, which may regulate the IFNgamma levels and, hence, modulate asthma pathogenesis. | 18385742 |