SNP data of: Disease - Allergic Rhinitis (AR) and
Biological sample - Nasal Tissues
SL. No. | Gene Name | SNP Involved | Comments | Reference (PMID) |
1 | VEGFA | rs1479430148 | AA genotype in rs1479430148 (VEGFA) was significantly associated with allergic rhinitis in mixed (pigmented-vascular) subtype. | 30215845 |
2 | STAT1 | rs3771300 | The polymorphism C39134A (rs3771300), located in a potentially cis acting regulatory element in STAT1 intron 24, was inversely related to atopy measured by skin prick test, total and specific serum IgE levels. STAT1 SNP C39134A may protect from atopic sensitization. | 17983380 |
3 | FOXP3 | rs2280883 | rs2280883 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
4 | FOXP3 | rs2232365 | rs2232365 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
5 | FOXP3 | rs3761548 | rs3761548 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
6 | FOXP3 | rs3761549 | rs3761549 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
7 | FOXP3 | rs3761547 | rs3761547 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
8 | FOXP3 | rs17847095 | rs17847095 showed significant correlation with the efficacy of allergic rhinitis specific immune therapy. | 26791767 |
9 | TLR4 | rs1927911 | Children carrying a minor rs1927911 (TLR4) allele may be at a higher risk of allergic rhinitis. | 23639307 |
10 | TLR4 | rs10759930 | Heterozygous and homozygous allele in rs10759930 is associated with allergic rhinitis. | 29798160 |
11 | TLR4 | rs1927911 | The risk for the development of Allergic Rhinitis or atopic Allergic Rhinitis subjects with the TLR4 CC genotype were highest when all the 3 early-life factors were present. | 25840711 |
12 | EGFR | rs4947972 | EGFR gene polymorphism (rs4947972) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults. | 20357714 |
13 | EGFR | rs12718945 | EGFR gene polymorphism (rs12718945) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults. | 20357714 |
14 | EGFR | rs2072454 | EGFR gene polymorphism (rs2072454) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults. | 20357714 |
15 | EGFR | rs2227983 | EGFR gene polymorphism (rs2227983) might be associated with presence of asymptomatic Airway Hyperresponsiveness (AHR) in young allergic adults. | 20357714 |
16 | TNFAIP3 | rs9494885 | The rs9494885 TC genotype and C allele were more frequent in Allergic Rhinitis patients compared with controls. The frequencies of the rs9494885 TT genotype and T allele were lower in AR patients than that in controls. | 26996111 |
17 | TNFAIP3 | rs7753873 | A higher frequency of the rs7753873 AC genotype and C allele and a lower frequency of the rs7753873 AA genotype and A allele were observed in Allergic Rhinitis patients as compared to healthy controls. | 26996111 |
18 | GLCCI1 | rs37973 | The GLCCI1 rs37973 variant is a risk factor for glucocorticoid resistance in Chinese patients with SAR who receive short-term INCS (Intranasal Corticosteroids) treatment. | 29981236 |