SNP data of: Disease - Atopic Dermatitis (AD) and
Biological sample - Skin Biopsies
SL. No. | Gene Name | SNP Involved | Comments | Reference (PMID) |
1 | DUSP1 | rs17075181 | In silico analysis of genome wide single nucleotide polymorphism data revealed evidence of an association between Atopic Dermatitis and rs17075181 near DUSP1. | 22445417 |
2 | STAT1 | rs3771300 | The polymorphism C39134A (rs3771300), located in a potentially cis acting regulatory element in STAT1 intron 24, was inversely related to atopy measured by skin prick test, total and specific serum IgE levels. STAT1 SNP C39134A may protect from atopic sensitization. | 17983380 |
3 | TLR4 | rs4986790 | The heterogeneous "AG" genotype of the TLR4 rs4986790 may be associated with increased susceptibility to atopic dermatitis in Caucasians. | 30273064 |
4 | TLR4 | rs4986790 | TLR4 gene mutant allele 896G is detected more frequently in children with Atopic Dermatitis with increased susceptibility to acute viral respiratory infections as compared to the control group. | 23821954 |
5 | FOXP3 | rs2232367 | A significant increase in the frequency of the mutated allele of 1651C>T in the male control group as compared to patients with atopy and autoimmunity. | 25982578 |
6 | FOXP3 | rs56066773 | The mutated allele of 7340C>T was significantly associated with the simultaneous presence of autoimmunity and atopy in male children. | 25982578 |
7 | VEGFA | rs2010963 | The rs2010963 SNP had a marginally significant effect on log-eosinophil counts in atopic dermatitis patients. | 23490417 |