RESULT OF MUTATION

Total records: 1 Records

 

Record No:1


ACCESS NO300113
GENE_NAMEIL13
dbSNP_IDrs20541
CHANGESC/T
ANCESTRAL_ALLELESC
FUNCTIONAL_CONSEQUENCESCoding region
DISEASEChildhood Asthma
POPULATIONChinese Han population
PMID 26613553
COMMENTSIndividuals homozygous for the risk alleles (GG) for rs20541 are at a higher risk for developing asthma compared with those without any risk homozygotes. IL13 rs20541 (G allele), IL4 rs2243250 (T allele), ADRB2 rs1042713 (A allele), and FCER1B rs569108 (G allele), four SNPs with significant sole effect on asthma, interact to confer a higher risk for the disease in Chinese Han children.



© Bose Institute, Kolkata, 2020. For any queries regarding DAAB (Version: 2), contact Dr. Sudipto Saha at  ssaha4@jcbose.ac.in