Expression data of: Disease - Atopic Dermatitis (AD) and
Biological sample - Skin Biopsies
SL. No. | Gene Name | DAAB-V2 ID | Expression Pattern | Reference (PMID) |
1 | STAT3 | D114466 | pSTAT3 was highly expressed in atopic lesional skin compared with normal control. | 27498343 |
2 | STAT3 | D114469 | pSTAT3 was overexpressed in atopic dermatitis lesions as compared to healthy skin. | 27711196 |
3 | STAT3 | D114526 | The expression of phosphorylated STAT3 was enhanced in skin samples of Atopic Dermatitis patients as compared to healthy controls. | 29528494 |
4 | STAT1 | D114467 | pSTAT1 was overexpressed in atopic dermatitis lesions as compared to healthy skin. | 27711196 |
5 | STAT1 | D110682 | STAT1 was exclusively upregulated in the European American Atopic Dermatitis patients. | 30223113 |
6 | HMGB1 | D114581 | The level of extracellular HMGB1 in Atopic Eczema skin was increased as compared with normal and psoriasis skin. | 28713916 |
7 | JAK2 | D114463 | pJAK2 was overexpressed in atopic dermatitis lesions as compared to healthy skin. | 27711196 |
8 | SIRT1 | D114445 | SIRT1 protein level is downregulated in human Atopic Dermatitis lesions and spongiotic dermatitis lesions as compared to healthy subjects. | 25445829 |
9 | CCL5 | D114520 | CCL5 was elevated in atopic dermatitis patients as compared to healthy controls. | 15948978 |
10 | CCL5 | D102412 | CCL5 mRNA expression is significantly increased in both lesional and non lesional skin of Atopic Dermatitis patients as compared to healthy skin. CCL5 protein is highly expressed in Atopic Dermatitis skin. | 22445417 |
11 | TSLP | D110690 | TSLP was exclusively upregulated in the African American Atopic Dermatitis patients. | 30223113 |
12 | TSLP | D102225 | Increased epidermal TSLP protein expression may serve as an early biomarker to predict the development of infantile Atopic Dermatitis. | 26879860 |
13 | NOTCH1 | D110341 | NOTCH1 was significantly down regulated in skin and T cells of Atopic Dermatitis patients as compared to healthy controls. | 30738053 |
14 | NOTCH1 | D114263 | Patients suffering from Atopic Dermatitis but not psoriasis or lichen planus, have a marked reduction of Notch receptor expression in the skin. | 20174635 |
15 | GATA3 | D110347 | GATA3 was down regulated in skin and T cells of Atopic Dermatitis patients as compared to healthy controls. | 30738053 |
16 | GATA3 | D110582 | GATA3 was down regulated in Atopic Dermatitis patients and psoriasis patients as compared to healthy controls. | 30118730 |
17 | GATA3 | D114495 | Decreased expression of GATA3 in the stratum spinosum and stratum granulosum of atopic dermatitis and psoriasis patients was noted when compared to healthy controls. | 28928464 |
18 | TGFB1 | D114459 | TGFB1 expression was markedly enhanced in both acute and particularly chronic lesions as compared to healthy skin. | 12704372 |
19 | TGFB1 | D114509 | In the skin of patients with Atopic Dermatitis, a significant increase of the level of gene expression was observed for TGFB1 as compared to healthy individuals. | 22299064 |
20 | TNFSF10 | D104443 | A significantly higher number of TRAIL (TNFSF10) positive mononuclear cells in the lesions of atopic dermatitis than in nonlesional skin of atopic dermatitis, normal skin and psoriasis. | 12752156 |
21 | TNFSF10 | D104441 | High TRAIL expression was observed in skin-infiltrating T cells of AD patients. | 16185275 |
22 | IL6 | D114503 | In the skin of patients with Atopic Dermatitis, a significant increase of the level of gene expression was observed for IL6 as compared to healthy individuals. | 22299064 |
23 | CXCL8 | D110143 | CXCL8 was significantly higher in lesional AD skin compared to healthy and non-lesional AD skin. | 29989151 |
24 | CXCL8 | D110616 | CXCL8 was significantly up regulated in Atopic Dermatitis patients as compared to healthy controls. | 30132823 |
25 | CXCL8 | D110706 | IL8 (CXCL8) was significantly more upregulated in European American. | 30223113 |
26 | CXCL8 | D114504 | In the skin of patients with Atopic Dermatitis, a significant increase of the level of gene expression was observed for IL8 (CXCL8) as compared to healthy individuals. | 22299064 |
27 | CXCL8 | D114534 | IL8 (CXCL8) level was significantly higher in atopic dermatitis patients as compared to healthy controls. IL8 level was associated with disease severity. | 22948248 |
28 | IL13 | D102350 | Increased expression of IL13 was found in intrinsic Atopic Dermatitis as compared to control. | 26841714 |
29 | IL13 | D110351 | IL13 was up regulated in skin and T cells of Atopic Dermatitis patients as compared to healthy controls. | 30738053 |
30 | IL13 | D110693 | IL13 mRNA was significantly upregulated in African American and European American Atopic Dermatitis lesional skin. | 30223113 |
31 | IL13 | D110733 | IL13 was increased in atopic dermatitis lesions as compared to psoriasis lesions and healthy skin of control subjects. | 30641038 |
32 | IL10 | D110689 | IL10 was exclusively upregulated in the African American Atopic Dermatitis patients. | 30223113 |
33 | IL10 | D110732 | IL10 was increased in atopic dermatitis lesions as compared to psoriasis lesions and healthy skin of control subjects. | 30641038 |
34 | IL10 | D114507 | In the skin of patients with Atopic Dermatitis, a significant increase of the level of gene expression was observed for IL10 as compared to healthy individuals. | 22299064 |