Expression data of: Disease - Asthma and
Biological sample - Airway Epithelial Cells
SL. No. | Gene Name | DAAB-V2 ID | Expression Pattern | Reference (PMID) |
1 | ORMDL3 | D102877 | The expression levels of ORMDL3 were higher in severe asthma than controls. | 27050946 |
2 | MAPKAPK5 | D114078 | MAPKAPK5 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
3 | SMAD5 | D103348 | SMAD5 was up regulated in atopic asthmatics as compared to healthy control. | 25515564 |
4 | CEACAM5 | D105250 | CEACAM5 was significantly overexpressed in epithelial brushings of severe asthmatics as compared to healthy subjects. | 28933920 |
5 | CEACAM5 | D106666 | CEACAM5 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
6 | CEACAM5 | D112805 | CEACAM5 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. | 28045928 |
7 | LOXL2 | D100185 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
8 | BMP2 | D103344 | BMP2 was up regulated in atopic asthmatics as compared to healthy control. | 25515564 |
9 | PLAU | D114112 | PLAU was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
10 | EREG | D100183 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
11 | MREG | D114079 | MREG was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
12 | SERTAD4 | D102041 | Highly expressed in both allergic rhinitis and asthma patients. | 24282527 |
13 | KLF4 | D100229 | This is an transcription factor significantly up regulated in asthma. | 17919147 |
14 | SMAD6 | D104321 | SMAD6 was upregulated in asthmatic Primary Airway Epithelial Cells (pAECs) as compared to non asthmatic pAECs. | 27221564 |
15 | KIF6 | D114116 | KIF6 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
16 | HAS3 | D104421 | Increased expression of HAS3 transcripts was noted in the Bronchial Epithelial Cells (BECs) from asthmatic children as compared with BECs from healthy children. | 27126823 |
17 | BMP8B | D103351 | BMP8B was up regulated in atopic asthmatics as compared to healthy control. | 25515564 |
18 | IGDCC4 | D114120 | IGDCC4 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
19 | EDNRA | D100193 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
20 | HAS2 | D104420 | Increased expression of HAS2 transcripts was noted in the Bronchial Epithelial Cells (BECs) from asthmatic children as compared with BECs from healthy children. | 27126823 |
21 | VDAC1 | D114060 | VDAC1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
22 | PSD3 | D102039 | Highly expressed in both allergic rhinitis and asthma patients. | 24282527 |
23 | FBXL7 | D105902 | FBXL7 was increased in male asthmatics. | 31095684 |
24 | KCNK6 | D113845 | KCNK6 was up regulated in severe asthma. | 27984699 |
25 | EHMT2 | D111224 | EHMT2 expression was up regulated in asthmatics as compared to healthy controls. | 28137284 |
26 | TNIP1 | D114181 | TNIP1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
27 | IER3 | D100257 | This gene is significantly up regulated in asthma. | 17919147 |
28 | AGMAT | D114068 | AGMAT was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
29 | SPARC | D114048 | SPARC was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
30 | ITGB8 | D100200 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
31 | NMU | D113847 | NMU was up regulated in severe asthma. | 27984699 |
32 | PXDN | D106788 | PXDN was significantly up regulated in asthmatics as compared to control group. | 29064281 |
33 | ABCC3 | D100236 | This gene codes for a metabolic enzyme significantly up regulated in asthma. | 17919147 |
34 | RAB3B | D100235 | This gene codes for a metabolic enzyme significantly up regulated in asthma. | 17919147 |
35 | RAB3B | D114045 | RAB3B was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
36 | TSC22D3 | D112801 | TSC22D3 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. | 28045928 |
37 | NPM3 | D114142 | NPM3 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
38 | FERMT1 | D113840 | FERMT1 was up regulated in severe asthma. | 27984699 |
39 | FERMT1 | D112775 | FERMT1 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. | 28045928 |
40 | CPSF1 | D112772 | CPSF1 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. | 28045928 |
41 | MARCH4 | D114001 | MARCH4 was significantly increased in severe asthmatics as compred to healthy controls. | 29769273 |
42 | S1PR1 | D106761 | S1PR1 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
43 | SPP1 | D113739 | SPP1 was increased in IL-6TS High asthma patients. | 29902480 |
44 | SPP1 | D106890 | SPP1 mRNA expression was over expressed in epithelial brushings of asthma patients as compared to healthy controls. | 27192552 |
45 | SPRY4 | D100203 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
46 | HBEGF | D100191 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
47 | NCEH1 | D114180 | NCEH1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
48 | TOR1AIP1 | D114182 | TOR1AIP1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
49 | TMEM200A | D106766 | TMEM200A was significantly up regulated in asthmatics as compared to control group. | 29064281 |
50 | PCDH7 | D102037 | Highly expressed in both allergic rhinitis and asthma patients. | 24282527 |
51 | SLC25A30 | D114159 | SLC25A30 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
52 | SOCS1 | D106767 | SOCS1 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
53 | SOCS3 | D113741 | The IL-6TS High subset of asthmatics (characterized by frequent exacerbations, eosinophilic airway inflammation and increased numbers of T cells and macrophages infiltrating the airway submucosa) did show a robust increase in the expression of SOCS3. | 29902480 |
54 | IL6R | D102876 | The expression levels of IL6R were consistently higher in asthma as compared to controls. | 27050946 |
55 | ARRDC3 | D100263 | This gene is significantly up regulated in asthma. | 17919147 |
56 | miR-17-5p | D113974 | miR-17-5p was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
57 | RNASE1 | D106791 | RNASE1 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
58 | miR-19b-3p | D113727 | miR-19b-3p expression was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
59 | SLC6A8 | D112797 | SLC6A8 was significantly over expressed in peripheral airways of severe asthmatics as compared to healthy subjects. | 28045928 |
60 | RBL2 | D103345 | RBL2 was up regulated in atopic asthmatics as compared to healthy control. | 25515564 |
61 | miR-582-3p | D113971 | miR-582-3p was significantly dereased in severe asthmatics as compared to healthy controls. | 29769273 |
62 | RGS16 | D106786 | RGS16 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
63 | LCLAT1 | D114103 | LCLAT1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
64 | SEMA7A | D106712 | SEMA7A was significantly up regulated in asthmatics as compared to control group. | 29064281 |
65 | NFKBIZ | D100289 | It is a regulatory gene upregulated in asthma. | 19710636 |
66 | miR-192-5p | D113977 | miR-192-5p was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
67 | miR-181b-5p | D106889 | Epithelial miR-181b-5p expression was decreased in subjects with asthma. | 27192552 |
68 | miR-135b-5p | D113731 | miR-135b-5p expression was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
69 | WDR72 | D106765 | WDR72 was significantly up regulated in asthmatics as compared to control group. | 29064281 |
70 | MRPS27 | D114080 | MRPS27 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
71 | PTPRB | D100219 | This is a receptor protein significantly up regulated in asthma. | 17919147 |
72 | EGFR | D113818 | EGFR expression was significantly higher in atopic asthmatic bronchial epithelial cells versus nonatopic controls. | 29367592 |
73 | SLC7A11 | D100248 | This gene codes for a transporter significantly up regulated in asthma. | 17919147 |
74 | miR-20a-5p | D113728 | miR-20a-5p expression was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
75 | miR-148a-3p | D113980 | miR-148a-3p was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
76 | TNFAIP3 | D100226 | This is an transcription factor significantly up regulated in asthma. | 17919147 |
77 | SFXN4 | D114104 | SFXN4 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
78 | TLR2 | D113748 | TLR2 expression was increased in IL-6TS High asthma patients. | 29902480 |
79 | XPNPEP3 | D114028 | XPNPEP3 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
80 | PHLDB2 | D105273 | PHLDB2 was significantly up regulated in epithelial brushings of severe asthmatics as compared to healthy subjects. | 28933920 |
81 | PSMD2 | D114044 | PSMD2 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
82 | MCL1 | D113740 | The IL-6TS High subset (characterized by frequent exacerbations, eosinophilic airway inflammation and increased numbers of T cells and macrophages infiltrating the airway submucosa) did show a robust increase in the expression of MCL-1 as compared to IL-6TS Low and healthy controls. | 29902480 |
83 | CCNYL1 | D114145 | CCNYL1 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
84 | TGFBR1 | D103347 | TGFBR1 was up regulated in atopic asthmatics as compared to healthy control. | 25515564 |
85 | miR-27b-3p | D113976 | miR-27b-3p was significantly decreased in severe asthmatics as compared to healthy controls. | 29769273 |
86 | TNF | D114160 | TNF was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
87 | TNF | D113757 | TNFalpha expression was increased in IL-6TS High asthma patients. | 29902480 |
88 | IL1A | D100176 | This is a cell communication protein significantly upregulated in asthma. | 17919147 |
89 | GDI2 | D114098 | GDI2 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
90 | CERS2 | D114149 | CERS2 was significantly increased in severe asthmatics as compared to control subjects. | 29769273 |
91 | F3 | D100218 | This is a receptor protein significantly up regulated in asthma. | 17919147 |